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SETDB1: SET domain bifurcated histone lysine methyltransferase 1
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Gene · 9869

Papers2,616

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

161 to 180 of 2,616

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TitleJournalYearPMIDFound bySource
Discovery of an efficacious KDM5B PROTAC degrader GT-653 up-regulating IFN response genes in prostate cancer.Eur J Med Chem202438749268PubTator, text miningPubMed
SETDB1 modulates the TGFβ response in Duchenne muscular dystrophy myotubes.Sci Adv202438691608PubTator, text miningPubMed
Diffuse Pleural Mesotheliomas with Genomic Near-Haploidization: A Newly Recognized Subset with Distinct Clinical, Histologic, and Molecular Features.Clin Cancer Res202438630790PubTator, text miningPubMed
SETDB1, an H3K9-specific methyltransferase: An attractive epigenetic target to combat cancer.Drug Discov Today202438614159PubTator, text miningPubMed
[Downregulation of SETDB1 suppresses epithelial mesenchymal transition and invasion and metastasis in oral cancer via SOX7 methylation].Shanghai Kou Qiang Yi Xue202438583021PubTator, text miningPubMed
Roles of endogenous retroviral elements in the establishment and maintenance of imprinted gene expression.Front Cell Dev Biol202438505259PubTator, text miningPubMed
Cytoplasmic localization of SETDB1‑induced Warburg effect via c‑MYC‑LDHA axis enhances migration and invasion in breast carcinoma.Int J Mol Med202438426579PubTator, text miningPubMed
The molecular basis of cell memory in mammals: The epigenetic cycle.Sci Adv202438416817PubTator, text miningPubMed
ATF7IP2/MCAF2 directs H3K9 methylation and meiotic gene regulation in the male germline.Genes Dev202438383062PubTator, text miningPubMed
SETDB1: Progress and prospects in cancer treatment potential and inhibitor research.Bioorg Chem202438377821PubTator, text miningPubMed
Structure-guided engineering enables E3 ligase-free and versatile protein ubiquitination via UBE2E1.Nat Commun202438341401PubTator, text miningPubMed
SETDB1 promotes progression through upregulation of SF3B4 expression and regulates the immunity in ovarian cancer.J Ovarian Res202438317200PubTator, text miningPubMed
Tumorous IRE1α facilitates CD8+T cells-dependent anti-tumor immunity and improves immunotherapy efficacy in melanoma.Cell Commun Signal202438291473PubTator, text miningPubMed
The novel mechanism facilitating chronic hepatitis B infection: immunometabolism and epigenetic modification reprogramming.Front Immunol202438288308PubTator, text miningPubMed
Pancreatic Neuroendocrine Tumors: Signaling Pathways and Epigenetic Regulation.Int J Mol Sci202438279330PubTator, text miningPubMed
AKT1 phosphorylation of cytoplasmic ME2 induces a metabolic switch to glycolysis for tumorigenesis.Nat Commun202438263319PubTator, text miningPubMed
Pharmaceutical Approach to Develop Novel Photosensitizer Nanoformulation: An Example of Design and Characterization Rationale of Chlorophyll α Derivative.Pharmaceutics202438258135PubTator, text miningPubMed
HIV Expression in Infected T Cell Clones.Viruses202438257808PubTator, text miningPubMed
The Role of Protein Methyltransferases in Immunity.Molecules202438257273PubTator, text miningPubMed
Exploring Potential Epigenetic Biomarkers for Colorectal Cancer Metastasis.Int J Mol Sci202438255946PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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