Gene · 987
LRBA: LPS responsive beige-like anchor protein
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. LRBA: LPS responsive beige-like anchor protein. Genes, record 987. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/987
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P50851 | Lipopolysaccharide-responsive and beige-like anchor protein | 2,863 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents17
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4640849 A2 | 2025-10-29 | 1100 | P50851 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 7339 | P50851 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 2416 | P50851 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 2416 | P50851 | Espacenet |
| JP 2025519096 A | 2025-06-24 | 1100 | P50851 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 7339 | P50851 | Espacenet |
| JP 2023510565 A | 2023-03-14 | 184 | P50851 | Espacenet |
| JP 2022141755 A | 2022-09-29 | 404 | P50851 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 47266 | P50851 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 150237 | P50851 | Espacenet |
1 to 10 of 17
See all 17 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants606
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | LRBA papers | Newest fiscal year |
|---|---|---|---|
| P30DK034854 | Integrated Epithelial and Muscosal Biology | 8 | 2025 |
| RC2DK118640 | COngenital Diarrhea and Enteropathy (PediCODE) Consortium and BioRepository | 7 | 2025 |
| ZIABC011436 | Viral Replication and Interactions with Host Factors | 7 | 2025 |
| ZIAAI000646 | Transgenic Animal Models Of Human Immune Defects | 5 | 2025 |
| ZIAAI000732 | Clinical, Immunological and Genetic Analyses of ALPS and Related Immunedysregulatory Disorders | 5 | 2025 |
| ZIAAI001059 | Defining New Human Immunodeficiency and Immunodysregulation Disorders | 5 | 2025 |
| ZIABC010814 | Elucidating the Regulation of HIV RNA Functions:Translation and Genome Packaging | 5 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 4 | 2025 |
| R01AI065617 | Genetic and Epigenetic Programming of Allergic Airway Inflammation | 4 | 2025 |
| ZIAAI000647 | Genes And Gene Products As Immunoadjuvants | 4 | 2025 |
1 to 10 of 606Source NIH's project files
See all 606 nih grantsPapers1,214
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Inborn Errors of Immunity Genotype: A Retrospective Study from the United Arab Emirates. | J Clin Immunol | 2026 | 42771195 | PubTator, text mining | PubMed |
| ABACHAI phase 2 clinical trial: Safety and efficacy of subcutaneous abatacept in patients with CTLA-4 insufficiency or LRBA deficiency. | J Allergy Clin Immunol | 2026 | 42763023 | PubTator, text mining | PubMed |
| Identifying and characterising a plant GH1 β-glucosidase that exhibits hydrolytic activity on N-linked glucopyranoside. | FEBS Open Bio | 2026 | 42563430 | PubTator, text mining | PubMed |
| Characterizing the membrane recruitment domain of BDCPs and its role in gray platelet syndrome. | J Cell Biol | 2026 | 42560489 | PubTator, text mining | PubMed |
| Clinical Spectrum and Therapeutic Options in Monogenic CTLA-4-, LRBA-, or SOCS1-Related Primary Immune Regulatory Disorders. | J Allergy Clin Immunol Pract | 2026 | 42409455 | PubTator, text mining | PubMed |
| Adult-Onset LRBA Deficiency Presenting with Rheumatoid Arthritis-Like Manifestations: A Case Report. | J Clin Immunol | 2026 | 42406167 | PubTator, text mining | PubMed |
| [Clinicopathological features of pediatric monogenic inflammatory bowel disease associated with both IL-10 and non-IL-10 pathways: a differential analysis]. | Zhonghua Bing Li Xue Za Zhi | 2026 | 42379848 | PubTator, text mining | PubMed |
| LRBA regulates actin cytoskeleton dynamics through NMIIA during B cell immune responses. | EMBO Rep | 2026 | 42286213 | PubTator, text mining | PubMed |
| Case Report: Different faces of LRBA deficiency in five Moroccan families. | Front Immunol | 2026 | 42148132 | PubTator, text mining | PubMed |
| The Intertwining Between Arthritis and Inborn Errors of Immunity. | J Clin Med | 2026 | 42123030 | PubTator, text mining | PubMed |
1 to 10 of 1,214
See all 1,214 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/987
GET https://conductscience.org/api/genes/v1/987/patents