Gene · 990
CDC6: cell division cycle 6
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. CDC6: cell division cycle 6. Genes, record 990. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/990
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q99741 | DNA replication factor CDC6 | 560 | 7 | Ensembl, GeneID, HGNC |
Source UniProt
Patents61
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4641201 A2 | 2025-10-29 | 212 | Q99741 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 4304 | Q99741 | Espacenet |
| US 12433888 B1 | 2025-10-07 | 17 | Q99741 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 212 | Q99741 | Espacenet |
| EP 4555325 A2 | 2025-05-21 | 17 | Q99741 | Espacenet |
| KR 1020250017231 A | 2025-02-04 | 4304 | Q99741 | Espacenet |
| JP 2024123008 A | 2024-09-10 | 5534 | Q99741 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 13755 | Q99741 | Espacenet |
| JP 2022092366 A | 2022-06-22 | 648 | Q99741 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 116726 | Q99741 | Espacenet |
1 to 10 of 61
See all 61 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,788
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | CDC6 papers | Newest fiscal year |
|---|---|---|---|
| R01GM045436 | Initiation of DNA Replication at Cell Origins in Yeast | 17 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 16 | 2025 |
| P01CA013106 | Targeting Transcription and Splicing in Cancer | 14 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 13 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 13 | 2025 |
| P30CA016056 | Roswell Park Cancer Center Support Grant | 11 | 2025 |
| ZIABC010411 | Initiation of DNA Replication in Mammalian Cells | 9 | 2025 |
| P30CA045508 | CSHL Cancer Center Support Grant | 8 | 2025 |
| P30CA076292 | Moffitt Cancer Center Support Grant | 8 | 2025 |
| P30CA014051 | Cancer Center Support (Core) Grant | 7 | 2025 |
1 to 10 of 1,788Source NIH's project files
See all 1,788 nih grantsPapers3,285
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Dual CHK1 and WNT Inhibition as a Synergistic Therapy for Gastrointestinal Neuroendocrine Carcinoma. | Cancer Res Commun | 2026 | 42811518 | PubTator, text mining | PubMed |
| AI-powered histopathology classifiers identify transcriptomic biomarkers associated with cell cycle regulation and increased mitotic activity in poorly differentiated neuroendocrine carcinoma. | Hum Genomics | 2026 | 42800881 | PubTator, text mining | PubMed |
| A human stem cell model of neuroblastoma identifies four chromosome 17q genes that drive tumor initiation and progression. | Cancer Lett | 2026 | 42648464 | PubTator, text mining | PubMed |
| Transcriptomic and experimental validation identify biomarkers and regulatory mechanisms associated with the aryl hydrocarbon receptor in nasopharyngeal carcinoma. | Transl Cancer Res | 2026 | 42591444 | PubTator, text mining | PubMed |
| Endocrine Phenotypes and Hormonal Treatment in Meier-Gorlin Syndrome: Report of Two Cases and a Systematic Review of Literature. | Clin Endocrinol (Oxf) | 2026 | 42496035 | PubTator, text mining | PubMed |
| CDK12 mediates the inhibition effect of mechanical unloading on osteoblast proliferation by regulating RNAPII transcription activation. | Bone Joint Res | 2026 | 42486479 | PubTator, text mining | PubMed |
| H3K4me3 and H3K27ac Promote ccRCC Proliferation Through the CDC6-EXOSC5 Axis. | Int J Mol Sci | 2026 | 42449933 | PubTator, text mining | PubMed |
| Molecular effects of ovarian stimulation for fertility preservation in breast cancer: a paired-biopsy analysis. | ESMO Open | 2026 | 42413327 | PubTator, text mining | PubMed |
| Ecological and evolutionary implications of a mobile genetic element-rich haloarchaeon with unique osmotic resilience. | Microbiol Spectr | 2026 | 42379816 | PubTator, text mining | PubMed |
| Identification and validation of stemness-associated hub genes in cervical cancer: a bioinformatics and experimental study. | World J Surg Oncol | 2026 | 42365339 | PubTator, text mining | PubMed |
1 to 10 of 3,285
See all 3,285 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/990
GET https://conductscience.org/api/genes/v1/990/patents?page=2