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Gene · 990

CDC6: cell division cycle 6

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CDC6: cell division cycle 6. Genes, record 990. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/990

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Gene

Symbol
CDC6
HGNC
Name
cell division cycle 6
HGNC
NCBI Gene ID
990
NCBI Gene
HGNC ID
HGNC:1744
HGNC
Ensembl
ENSG00000094804
NCBI Gene
Aliases
CDC18L, HsCDC18, HsCDC6, MGORS5
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q99741DNA replication factor CDC65607Ensembl, GeneID, HGNC

Source UniProt

Patents61

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4641201 A22025-10-29212Q99741Espacenet
EP 4641202 A22025-10-294304Q99741Espacenet
US 12433888 B12025-10-0717Q99741Espacenet
JP 2025517969 A2025-06-12212Q99741Espacenet
EP 4555325 A22025-05-2117Q99741Espacenet
KR 1020250017231 A2025-02-044304Q99741Espacenet
JP 2024123008 A2024-09-105534Q99741Espacenet
US 11446398 B22022-09-2013755Q99741Espacenet
JP 2022092366 A2022-06-22648Q99741Espacenet
JP 2022524081 A2022-04-27116726Q99741Espacenet

1 to 10 of 61

See all 61 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,788

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCDC6 papersNewest fiscal year
R01GM045436Initiation of DNA Replication at Cell Origins in Yeast172025
P30CA016672Cancer Center Support Grant162025
P01CA013106Targeting Transcription and Splicing in Cancer142025
P30CA008748Cancer Center Support Grant132025
P30CA016086Cancer Center Support Grant132025
P30CA016056Roswell Park Cancer Center Support Grant112025
ZIABC010411Initiation of DNA Replication in Mammalian Cells92025
P30CA045508CSHL Cancer Center Support Grant82025
P30CA076292Moffitt Cancer Center Support Grant82025
P30CA014051Cancer Center Support (Core) Grant72025

1 to 10 of 1,788Source NIH's project files

See all 1,788 nih grants

Papers3,285

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Dual CHK1 and WNT Inhibition as a Synergistic Therapy for Gastrointestinal Neuroendocrine Carcinoma.Cancer Res Commun202642811518PubTator, text miningPubMed
AI-powered histopathology classifiers identify transcriptomic biomarkers associated with cell cycle regulation and increased mitotic activity in poorly differentiated neuroendocrine carcinoma.Hum Genomics202642800881PubTator, text miningPubMed
A human stem cell model of neuroblastoma identifies four chromosome 17q genes that drive tumor initiation and progression.Cancer Lett202642648464PubTator, text miningPubMed
Transcriptomic and experimental validation identify biomarkers and regulatory mechanisms associated with the aryl hydrocarbon receptor in nasopharyngeal carcinoma.Transl Cancer Res202642591444PubTator, text miningPubMed
Endocrine Phenotypes and Hormonal Treatment in Meier-Gorlin Syndrome: Report of Two Cases and a Systematic Review of Literature.Clin Endocrinol (Oxf)202642496035PubTator, text miningPubMed
CDK12 mediates the inhibition effect of mechanical unloading on osteoblast proliferation by regulating RNAPII transcription activation.Bone Joint Res202642486479PubTator, text miningPubMed
H3K4me3 and H3K27ac Promote ccRCC Proliferation Through the CDC6-EXOSC5 Axis.Int J Mol Sci202642449933PubTator, text miningPubMed
Molecular effects of ovarian stimulation for fertility preservation in breast cancer: a paired-biopsy analysis.ESMO Open202642413327PubTator, text miningPubMed
Ecological and evolutionary implications of a mobile genetic element-rich haloarchaeon with unique osmotic resilience.Microbiol Spectr202642379816PubTator, text miningPubMed
Identification and validation of stemness-associated hub genes in cervical cancer: a bioinformatics and experimental study.World J Surg Oncol202642365339PubTator, text miningPubMed

1 to 10 of 3,285

See all 3,285 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/990

GET https://conductscience.org/api/genes/v1/990/patents?page=2