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MFN2: mitofusin 2

1 protein, 68 patents, 0 drugs, 0 trials, 3,398 NIH grants and 6,972 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolMFN2HGNC
Namemitofusin 2HGNC
NCBI Gene ID9927NCBI Gene
HGNC IDHGNC:16877HGNC
EnsemblENSG00000116688NCBI Gene
AliasesCMT2A, CMT2A2, CMT2A2A, CMT2A2B, CPRP1, HMSN6A, HSG, KIAA0214, MARF, MSLNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
O95140Mitofusin-27573Ensembl, GeneID, HGNCUniProt

Patents 68

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026515744 A2026-05-1925O95140Espacenet
JP 2026004568 A2026-01-1453912O95140Espacenet
JP 2026004568 A2026-01-1453915O95140Espacenet
EP 4650780 A22025-11-19905O95140Espacenet
EP 4620519 A22025-09-2423O95140Espacenet
EP 4620520 A22025-09-2423O95140Espacenet
EP 4620521 A22025-09-2423O95140Espacenet
JP 2025529142 A2025-09-042609O95140Espacenet
US 12371689 B22025-07-292609O95140Espacenet
JP 2025517970 A2025-06-12905O95140Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3398

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30AG028740University of Florida Older Americans Independence Center (OAIC)132,025NIH's project files
P30DK020572Michigan Diabetes Research Center (MDRC)132,025NIH's project files
ZIANS002859Targeting Protein Aggregates for Autophagosomal Degradation132,025NIH's project files
ZIANS003123Role of mitochondria in neurodegenerative diseases122,025NIH's project files
R01NS072248Genome Studies in Hereditary Spastic Paraplegia- Beyond the Exome92,025NIH's project files
R01GM118509Determining the mechanism of mitochondrial outer membrane fusion82,025NIH's project files
R35GM128915Molecular Principles Governing Mitochondrial and Peroxisomal Remodeling as Drivers of Cell Fate and Identity82,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award82,025NIH's project files
ZIANS003127Mechanisms of Autophagy82,025NIH's project files
P30CA010815Consolidated Basic Cancer Research Program72,025NIH's project files

Papers 6972

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42799779PubTator, text miningPubMed
42791642PubTator, text miningPubMed
42787219PubTator, text miningPubMed
42780667PubTator, text miningPubMed
42771491PubTator, text miningPubMed
42761440PubTator, text miningPubMed
42760986PubTator, text miningPubMed
42751568PubTator, text miningPubMed
42747977PubTator, text miningPubMed
42738805PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license