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Gene · 994

CDC25B: cell division cycle 25B

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CDC25B: cell division cycle 25B. Genes, record 994. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/994

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Gene

Symbol
CDC25B
HGNC
Name
cell division cycle 25B
HGNC
NCBI Gene ID
994
NCBI Gene
HGNC ID
HGNC:1726
HGNC
Ensembl
ENSG00000101224
NCBI Gene
Aliases
MPIP2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P30305M-phase inducer phosphatase 258019Ensembl, GeneID, HGNC

Source UniProt

Patents33

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1440771P30305Espacenet
EP 4650780 A22025-11-191170P30305Espacenet
EP 4641201 A22025-10-29835P30305Espacenet
EP 4641202 A22025-10-294427P30305Espacenet
US 12433888 B12025-10-0711P30305Espacenet
JP 2025517969 A2025-06-12835P30305Espacenet
JP 2025517970 A2025-06-121170P30305Espacenet
EP 4555325 A22025-05-2111P30305Espacenet
KR 1020250017231 A2025-02-044427P30305Espacenet
US 11987613 B22024-05-2111P30305Espacenet

1 to 10 of 33

See all 33 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,099

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCDC25B papersNewest fiscal year
P30CA016672Cancer Center Support Grant212025
P30CA016058Cancer Center Support Grant62025
P30CA008748Cancer Center Support Grant52025
P30CA044579University of Virginia Cancer Center Support Grant52025
R01AG011085Ubiquitin‐mediated proteolysis and cell cycle control52025
P30CA016086Cancer Center Support Grant42025
P30CA036727Buffett Cancer Center Support Grant42025
P30CA047904Cancer Center Support Grant42025
ZIACP010121Molecular Epidemiology Studies of Occupational and Environmental Exposures42025
P01AI127335Human Cytomegalovirus dysregulation of host hematopoietic progenitor cell signaling pathways to modulate latency and reactivation32025

1 to 10 of 1,099Source NIH's project files

See all 1,099 nih grants

Papers2,079

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Correction to "IER5 Negatively Regulates Cdc25B Expression in HeLa Cells After Gamma Ray Irradiation".Biomed Res Int202642608995PubTator, text miningPubMed
Identification and Validation of an E2F Targets-Related Gene Signature Risk Score Predicting the Prognosis of Patients with Uveal Melanoma.Ocul Oncol Pathol202642553888PubTator, text miningPubMed
Novel CDK-independent function of CDC25 phosphatases in mRNA translation.EMBO Rep202642448957PubTator, text miningPubMed
Differential DNA Methylation and Delirium After Anesthesia and Surgery.medRxiv202642369472PubTator, text miningPubMed
Exploring a critical time window for FOXM1-driven bladder injury in chronic arsenic exposure.Ecotoxicol Environ Saf202642190387PubTator, text miningPubMed
Chemical components from Uncaria gambir (W.Hunter) Roxb. and their preliminary bioactivities in CDC25B phosphatase inhibition and vasodilatory activity.Nat Prod Res202642176307PubTator, text miningPubMed
The Binding of 3-O-Methylfluorescein Phosphate to the Catalytic Domain of the Human CDC25B Phosphatase: A Structural Investigation.Chembiochem202641906666PubTator, text miningPubMed
AI-derived prognostic model identifies high-risk gene signatures in pediatric gliomas.Front Immunol202641878416PubTator, text miningPubMed
A hybrid molecular-imaging model for high-accuracy early colorectal cancer diagnosis.J Gastrointest Oncol202641816600PubTator, text miningPubMed
Paired-Box (PAX) Gene Signatures as a Biomarker of Breast Cancer Progression.Int J Mol Sci202641752124PubTator, text miningPubMed

1 to 10 of 2,079

See all 2,079 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/994

GET https://conductscience.org/api/genes/v1/994/patents?page=2