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Gene · 9961

MVP: major vault protein

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. MVP: major vault protein. Genes, record 9961. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/9961

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Gene

Symbol
MVP
HGNC
Name
major vault protein
HGNC
NCBI Gene ID
9961
NCBI Gene
HGNC ID
HGNC:7531
HGNC
Ensembl
ENSG00000013364
NCBI Gene
Aliases
LRP, VAULT1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q14764Major vault protein89320Ensembl, GeneID, HGNC

Source UniProt

Patents83

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1452454Q14764Espacenet
JP 2026004568 A2026-01-1452455Q14764Espacenet
EP 4650780 A22025-11-197429Q14764Espacenet
EP 4641201 A22025-10-297390Q14764Espacenet
JP 2025517969 A2025-06-127390Q14764Espacenet
JP 2025517970 A2025-06-127429Q14764Espacenet
JP 2025032204 A2025-03-1131898Q14764Espacenet
JP 2025032204 A2025-03-1131908Q14764Espacenet
EP 4461818 A22024-11-1331898Q14764Espacenet
EP 4461818 A22024-11-1331908Q14764Espacenet

1 to 10 of 83

See all 83 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,075

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleMVP papersNewest fiscal year
P30CA016672Cancer Center Support Grant102025
P30DK058404Molecular and Cellular Basis for Digestive Diseases42025
P30CA016056Roswell Park Cancer Center Support Grant32025
P30CA068485Cancer Center Support Grant32025
P30ES010126UNC Center for Environmental Health and Susceptibility32025
R01GM071940High-Resolution CryoEM Reconstruction of Large Complexes32025
R35CA197570Early to Late Events in Colorectal Neoplasia: Basic Biology to Clinical Implementation32025
P20GM103446Delaware INBRE22025
P30CA033572Cancer Center Support Grant22025
P50CA127001SPORE in Brain Cancer22025

1 to 10 of 1,075Source NIH's project files

See all 1,075 nih grants

Papers1,914

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
[Establishment of a Doxorubicin-Resistant Acute Myeloid Leukemia Cell Line and Study on Its Drug Resistance Mechanisms].Zhongguo Shi Yan Xue Ye Xue Za Zhi202642544649PubTator, text miningPubMed
Circulating mRNA and miRNA Signatures Used as Predictive Markers of Lifestyle Modification Outcomes in Pediatric Obesity Management.Horm Res Paediatr202642391183PubTator, text miningPubMed
Redox-dependent S-glutathionylation of Aurora-A kinase by Gstp promotes postsynaptic maturation.J Cell Biol202642283724PubTator, text miningPubMed
PRDM16 Drives Thyroid Cancer Differentiation via a TRIM58-MVP Axis to Suppress MAPK and PI3K/AKT Signaling.Int J Biol Sci202642157931PubTator, text miningPubMed
TIE2 Interacts with Major Vault Protein and Modulates Angiogenic Function in Human Retinal Microvascular Endothelial Cells Through PI3K/AKT Signaling.Curr Eye Res202642132222PubTator, text miningPubMed
Identifying THBS3 as a potentially viable therapeutic target for gastric cancer: Intergration of Mendelian randomization and cell experiments validation study.Int J Biol Macromol202642067089PubTator, text miningPubMed
Banxia Xiexin Decoction inhibits chemoresistance in gastric cancer by regulating BMSC-derived exosome-mediated G3BP1-YWHAZ protein interaction.Am J Transl Res202642007146PubTator, text miningPubMed
MG53 Coordinates Macrophage Polarization and Neuroimmune Coupling to Promote Corneal Nerve Regeneration via the MPEG1-MVP-STAT6 Axis.Adv Sci (Weinh)202641961488PubTator, text miningPubMed
Predictive value of electrocardiogram Morphology-Voltage-P wave duration score for new episodes of atrial fibrillation in patients with acute myocardial infarction: a retrospective study.Front Cardiovasc Med202641884639PubTator, text miningPubMed
Specific GPCRs elicit unique extracellular vesicle miRNA array signatures.Elife202641860956PubTator, text miningPubMed

1 to 10 of 1,914

See all 1,914 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/9961

GET https://conductscience.org/api/genes/v1/9961/patents?page=2