Gene · 9966
TNFSF15: TNF superfamily member 15
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. TNFSF15: TNF superfamily member 15. Genes, record 9966. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/9966
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O95150 | Tumor necrosis factor ligand superfamily member 15 | 251 | 7 | Ensembl, GeneID, HGNC |
Source UniProt
Patents255
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4820526 A1 | 2026-10-14 | 2 | O95150 | Espacenet |
| EP 4719473 A1 | 2026-04-08 | 2050 | O95150 | Espacenet |
| WO 2026019692 A2 | 2026-01-22 | 15 | O95150 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 68640 | O95150 | Espacenet |
| JP 2026500100 A | 2026-01-06 | 2050 | O95150 | Espacenet |
| US 12509523 B1 | 2025-12-30 | 2493 | O95150 | Espacenet |
| WO 2025245508 A1 | 2025-11-27 | 81 | O95150 | Espacenet |
| US 12466890 B1 | 2025-11-11 | 2493 | O95150 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 13613 | O95150 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 16538 | O95150 | Espacenet |
1 to 10 of 255
See all 255 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,245
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | TNFSF15 papers | Newest fiscal year |
|---|---|---|---|
| P30DK063491 | Diabetes Research Center (DRC) | 15 | 2025 |
| U01DK062413 | Determining genomic and host-environment contributions to IBD phenotypes | 15 | 2025 |
| U01DK062422 | Mount Sinai NYC Genetics Research Center: Multi-omic integration across data-types, cell niches and populations | 14 | 2025 |
| U01DK062431 | IBD Gene Mapping by Clinical and Population Subset | 12 | 2025 |
| P30DK043351 | Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital | 10 | 2025 |
| U19AI070535 | Airway Inflammation and Airway Remodeling in Severe Asthma | 10 | 2025 |
| U01DK062423 | Genomic and Immunologic Characterization of Inflammatory Bowel Disease and its Phenotypes | 9 | 2025 |
| U01DK062432 | Montreal-Boston Collaborative GRC | 9 | 2025 |
| R01EY024484 | Immune Mechanisms in Ocular Graft versus Host Disease | 8 | 2025 |
| P30DK034989 | Yale Liver Center | 7 | 2025 |
1 to 10 of 1,245Source NIH's project files
See all 1,245 nih grantsPapers2,280
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Review Article: Beyond the Therapeutic Ceiling in Inflammatory Bowel Disease-Mechanism-Based Positioning and Emerging Therapeutic Strategies. | Aliment Pharmacol Ther | 2026 | 42827330 | PubTator, text mining | PubMed |
| Network of interactions between the tumor necrosis factor superfamily members and small S100 proteins. | PLoS One | 2026 | 42809589 | PubTator, text mining | PubMed |
| Preclinical and clinical evaluation of systemic danegaptide for the treatment of nonproliferative diabetic retinopathy. | Sci Transl Med | 2026 | 42777083 | PubTator, text mining | PubMed |
| Tumor necrosis factor-like cytokine 1 A antagonists for inflammatory bowel disease: A systematic review and meta-analysis. | Indian J Gastroenterol | 2026 | 42766208 | PubTator, text mining | PubMed |
| Targeted Therapies in Inflammatory Bowel Disease: Mechanisms, Comparative Evidence, and Clinical Translation. | J Clin Med | 2026 | 42739758 | PubTator, text mining | PubMed |
| Targeting the TL1A pathway in inflammatory bowel disease: mechanistic insights and emerging therapeutic pipeline. | Inflamm Bowel Dis | 2026 | 42660189 | PubTator, text mining | PubMed |
| TL1A-DR3 Signaling in Inflammatory Bowel Disease: From Pathogenesis to Therapeutic Targeting. | Kurume Med J | 2026 | 42633936 | PubTator, text mining | PubMed |
| Circulating levels of TL1A and its decoy receptor DcR3 in systemic sclerosis. | Clin Rheumatol | 2026 | 42622765 | PubTator, text mining | PubMed |
| Pharmacologic management of metabolic and alcohol-associated liver disease. | Metab Target Organ Damage | 2026 | 42577825 | PubTator, text mining | PubMed |
| TL1A(TNFSF15)-ENO1 axis promotes osteoarthritis by disrupting redox homeostasis via the PI3K/AKT pathway. | Osteoarthritis Cartilage | 2026 | 42567404 | PubTator, text mining | PubMed |
1 to 10 of 2,280
See all 2,280 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/9966
GET https://conductscience.org/api/genes/v1/9966/patents?page=2