Gene · 9972
NUP153: nucleoporin 153
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. NUP153: nucleoporin 153. Genes, record 9972. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/9972
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P49790 | Nuclear pore complex protein Nup153 | 1,475 | 12 | Ensembl, GeneID, HGNC |
Source UniProt
Patents21
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 56314 | P49790 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 2009 | P49790 | Espacenet |
| EP 4640849 A2 | 2025-10-29 | 241 | P49790 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 1576 | P49790 | Espacenet |
| JP 2025519096 A | 2025-06-24 | 241 | P49790 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 1576 | P49790 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 2009 | P49790 | Espacenet |
| JP 2023086836 A | 2023-06-22 | 107 | P49790 | Espacenet |
| JP 2023505833 A | 2023-02-13 | 107 | P49790 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 58796 | P49790 | Espacenet |
1 to 10 of 21
See all 21 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,143
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | NUP153 papers | Newest fiscal year |
|---|---|---|---|
| R01AI052014 | HIV-1 Preintegration Trafficking and Nuclear Localization | 25 | 2025 |
| P30CA042014 | Cancer Center Support Grant | 15 | 2025 |
| R01AI120860 | Development of HIV capsid-targeting antivirals that affect immune response by modulating capsid stability and have improved resistance profiles | 13 | 2025 |
| P30CA014195 | Cancer Center Support Grant (CCSG) | 10 | 2025 |
| R01AI129862 | Imaging early steps of HIV-1 infection and virus-host factor interactions | 10 | 2025 |
| R37AI039394 | Biochemical Mechanism of HIV DNA Integration | 8 | 2025 |
| U54AI170791 | Pittsburgh Center for HIV Protein Interactions (PCHPI) | 8 | 2025 |
| U54AI170855 | Behavior of HIV in Viral Environments (B-HIVE) | 8 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 7 | 2025 |
| R01AI100720 | Evolutionary potential of HIV-1 capsid: mechanisms and consequences | 7 | 2025 |
1 to 10 of 1,143Source NIH's project files
See all 1,143 nih grantsPapers1,505
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Mechanistic Insights into HIV-1 Capsid Interactions with CPSF6. | bioRxiv | 2026 | 42818617 | PubTator, text mining | PubMed |
| Expandable DNA-origami rings as a nanomechanical platform for studying disordered nucleoporins. | bioRxiv | 2026 | 42818085 | PubTator, text mining | PubMed |
| Comparative Kd analysis of the interaction between aggregation-prone Nup153 3-2 and KapN. | J Magn Reson | 2026 | 42691522 | PubTator, text mining | PubMed |
| NUP153 immunoreactivity in neuroendocrine neoplasms supports the diagnosis of NET versus NEC and is modulated by post-translational modifications. | J Neuroendocrinol | 2026 | 42586948 | PubTator, text mining | PubMed |
| HIV-1 capsid interactions with Nuclear Pore Complex components support nuclear entry via affinity gradient. | Proc Natl Acad Sci U S A | 2026 | 42412942 | PubTator, text mining | PubMed |
| Progerin-induced nuclear envelope remodeling is shaped by cell division and NUP153. | J Cell Sci | 2026 | 42237879 | PubTator, text mining | PubMed |
| Discovery of 4-Quinazolinone-Containing Phenylalanine Derivatives as Potent, Resistant-Tolerant HIV Capsid Inhibitors. | MedComm (2020) | 2026 | 42087906 | PubTator, text mining | PubMed |
| Proviral NUP153 binding to viral proteins and RNA regulates structural-nonstructural protein ratios in orthoflavivirus infection. | Nat Commun | 2026 | 41951628 | PubTator, text mining | PubMed |
| Transcriptome-driven constraint-based modelling reveals metabolic targets for ovarian cancer. | Cancer Metab | 2026 | 41857765 | PubTator, text mining | PubMed |
| Lamin B receptor upregulation in metastatic melanoma causes nuclear envelope fragility in confined migration during cancer invasion. | Proc Natl Acad Sci U S A | 2026 | 41706894 | PubTator, text mining | PubMed |
1 to 10 of 1,505
See all 1,505 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/9972
GET https://conductscience.org/api/genes/v1/9972/patents?page=2