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Gene · 9972

NUP153: nucleoporin 153

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. NUP153: nucleoporin 153. Genes, record 9972. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/9972

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Gene

Symbol
NUP153
HGNC
Name
nucleoporin 153
HGNC
NCBI Gene ID
9972
NCBI Gene
HGNC ID
HGNC:8062
HGNC
Ensembl
ENSG00000124789
NCBI Gene
Aliases
HNUP153, N153
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P49790Nuclear pore complex protein Nup1531,47512Ensembl, GeneID, HGNC

Source UniProt

Patents21

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1456314P49790Espacenet
EP 4650780 A22025-11-192009P49790Espacenet
EP 4640849 A22025-10-29241P49790Espacenet
EP 4641201 A22025-10-291576P49790Espacenet
JP 2025519096 A2025-06-24241P49790Espacenet
JP 2025517969 A2025-06-121576P49790Espacenet
JP 2025517970 A2025-06-122009P49790Espacenet
JP 2023086836 A2023-06-22107P49790Espacenet
JP 2023505833 A2023-02-13107P49790Espacenet
US 11446398 B22022-09-2058796P49790Espacenet

1 to 10 of 21

See all 21 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,143

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleNUP153 papersNewest fiscal year
R01AI052014HIV-1 Preintegration Trafficking and Nuclear Localization252025
P30CA042014Cancer Center Support Grant152025
R01AI120860Development of HIV capsid-targeting antivirals that affect immune response by modulating capsid stability and have improved resistance profiles132025
P30CA014195Cancer Center Support Grant (CCSG)102025
R01AI129862Imaging early steps of HIV-1 infection and virus-host factor interactions102025
R37AI039394Biochemical Mechanism of HIV DNA Integration82025
U54AI170791Pittsburgh Center for HIV Protein Interactions (PCHPI)82025
U54AI170855Behavior of HIV in Viral Environments (B-HIVE)82025
P30CA021765Cancer Center Support Grant (CCSG)72025
R01AI100720Evolutionary potential of HIV-1 capsid: mechanisms and consequences72025

1 to 10 of 1,143Source NIH's project files

See all 1,143 nih grants

Papers1,505

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Mechanistic Insights into HIV-1 Capsid Interactions with CPSF6.bioRxiv202642818617PubTator, text miningPubMed
Expandable DNA-origami rings as a nanomechanical platform for studying disordered nucleoporins.bioRxiv202642818085PubTator, text miningPubMed
Comparative Kd analysis of the interaction between aggregation-prone Nup153 3-2 and KapN.J Magn Reson202642691522PubTator, text miningPubMed
NUP153 immunoreactivity in neuroendocrine neoplasms supports the diagnosis of NET versus NEC and is modulated by post-translational modifications.J Neuroendocrinol202642586948PubTator, text miningPubMed
HIV-1 capsid interactions with Nuclear Pore Complex components support nuclear entry via affinity gradient.Proc Natl Acad Sci U S A202642412942PubTator, text miningPubMed
Progerin-induced nuclear envelope remodeling is shaped by cell division and NUP153.J Cell Sci202642237879PubTator, text miningPubMed
Discovery of 4-Quinazolinone-Containing Phenylalanine Derivatives as Potent, Resistant-Tolerant HIV Capsid Inhibitors.MedComm (2020)202642087906PubTator, text miningPubMed
Proviral NUP153 binding to viral proteins and RNA regulates structural-nonstructural protein ratios in orthoflavivirus infection.Nat Commun202641951628PubTator, text miningPubMed
Transcriptome-driven constraint-based modelling reveals metabolic targets for ovarian cancer.Cancer Metab202641857765PubTator, text miningPubMed
Lamin B receptor upregulation in metastatic melanoma causes nuclear envelope fragility in confined migration during cancer invasion.Proc Natl Acad Sci U S A202641706894PubTator, text miningPubMed

1 to 10 of 1,505

See all 1,505 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/9972

GET https://conductscience.org/api/genes/v1/9972/patents?page=2