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Paper102726

Pre-B and B cells in rabbits. Ontogeny and allelic exclusion of kappa light chain genes.

Hayward AR and 4 others. J Exp Med, 1978. Cited by 60 papers, by iCite.

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ConductScience Library. Pre-B and B cells in rabbits. Ontogeny and allelic exclusion of kappa light chain genes. Papers, record 102726. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/102726

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Pre-B and B cells in rabbits. Ontogeny and allelic exclusion of kappa light chain genes.
PubMed
Journal
J Exp Med
PubMed
Year
1978
PubMed
Publication types
Journal Article, Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
60
iCite
Relative citation ratio, by iCite
1.27
iCite
Revised in PubMed
2019-05-08
PubMed

Authors5

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Hayward ARA R
2Simons MAM A
3Lawton ARA R
4Mage RGR G
5Cooper MDM D

Source PubMed

Topics12

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
B-LymphocytesMajor topic
Immunoglobulin Light ChainsMajor topic
Immunoglobulin kappa-ChainsMajor topic
Receptors, Antigen, B-CellMajor topic
Alleles
Animals
Binding Sites
Cell Differentiation
Complement System Proteins
Immunoglobulin Allotypes
Liver
Rabbits

Source PubMed

References22

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
11,268,946Evidence for active synthesis of two allelic b locus markers by single lymphocytes from heterozygous rabbits.Cell Immunol1976https://conductscience.org/library/papers/1268946PubMed
296,180Pre-B cells: bone marrow persistence in anti-mu-suppressed mice, conversion to B lymphocytes, and recovery after destruction by cyclophosphamide.J Immunol1978https://conductscience.org/library/papers/96180PubMed
3351,064Sequential expression of immunoglobulin on developing mouse B lymphocytes: a systematic survey that suggests a model for the generation of immunoglobulin isotype diversity.J Immunol1978https://conductscience.org/library/papers/351064PubMed
44,100,380Membrane-associated immunoglobulin of rabbit peripheral blood lymphocytes: allelic exclusion at the b locus.Proc Natl Acad Sci U S A1971https://conductscience.org/library/papers/4100380PubMed
54,126,772Immunoglobulin (Ig) allotype markers on rabbit lymphocytes: separation of cells bearing different allotypes and demonstration of the binding of Ig to lymphoid cell membranes.J Immunol1973https://conductscience.org/library/papers/4126772PubMed
6412,679Immunofluorescent studies of the development of pre-B cells, B lymphocytes and immunoglobulin isotype diversity in humans.Eur J Immunol1977https://conductscience.org/library/papers/412679PubMed
74,137,513A rabbit with the allotypic phenotype: ala2a3 b4b5b6.J Immunol1974https://conductscience.org/library/papers/4137513PubMed
84,159,057Cellular localization of immunoglobulins with different allotypic specificities in rabbit lymphoid tissues.J Exp Med1965https://conductscience.org/library/papers/4159057PubMed
94,160,817Rabbit lymphoid cells differentiated with respect to alpha-, gamma-, and mu- heavy polypeptide chains and to allotypic markers Aa1 and Aa2.J Exp Med1966https://conductscience.org/library/papers/4160817PubMed
104,180,052The synthesis of secretory IgA in the rabbit. I. Evidence for synthesis as an 11 S dimer.J Immunol1969https://conductscience.org/library/papers/4180052PubMed
114,194,773Immunoglobulin allotypic determinants on rabbit lymphocytes.Nature1970https://conductscience.org/library/papers/4194773PubMed
124,545,162Ontogeny of B lymphocytes. II. Relative rates of appearance of lymphocytes bearing surface immunoglobulin and complement receptors.J Exp Med1974https://conductscience.org/library/papers/4545162PubMed
134,546,833Inhibition of complement-dependent lymphocyte rosette formation: a possible test for activated complement products.Eur J Immunol1974https://conductscience.org/library/papers/4546833PubMed
144,582,840Allotype suppression in the rabbit. I. The ontogeny of cells bearing immunoglobulin of paternal allotype and the fate of these cells after treatment with antiallotype antisera.J Exp Med1973https://conductscience.org/library/papers/4582840PubMed
155,036,149Purification and effectiveness of anti-allotype antibodies in suppression of rabbit immunoglobulin allotypes.Immunochemistry1972https://conductscience.org/library/papers/5036149PubMed
16563,292Allelic allotype inclusion and exclusion among rabbit Ig-bearing lymphocytes of peripheral blood and lymphoid organs.Cell Immunol1977https://conductscience.org/library/papers/563292PubMed
1764,307
Surface immunoglobulin on rabbit lymphoid cells. III. Double expression and separate endocytosis of surface immunoglobulin allotypes on heterozygous lymphocytes demonstrated by immunoelectron microscopic labeling.
Cell Immunol1976https://conductscience.org/library/papers/64307PubMed
1867,144
Murine plasma cells secreting more than one class of immunoglobulin heavy chain. II. SAMM 368--a plasmacytoma secreting IgG2b-kappa and IgA-kappa immunoglobulins which do not share idiotypic determinants.
J Immunol1977https://conductscience.org/library/papers/67144PubMed
1970,309Ontogeny of murine B lymphocytes: development of Ig synthesis and of reactivities to mitogens and to anti-Ig-antibodies.Cold Spring Harb Symp Quant Biol1977https://conductscience.org/library/papers/70309PubMed
20803,412Appearance of lymphocyte surface markers and functional responses in neonatal and young rabbit spleens.Cell Immunol1975https://conductscience.org/library/papers/803412PubMed

See all 22 references

Cited by13

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 60 citations.

PMIDTitleJournalYearIn PapersSource
33,805,607Immunity against Lagovirus europaeus and the Impact of the Immunological Studies on Vaccination.Vaccines (Basel)2021https://conductscience.org/library/papers/33805607PubMed
32,636,848Pulmonary Consequences of Prenatal Inflammatory Exposures: Clinical Perspective and Review of Basic Immunological Mechanisms.Front Immunol2020https://conductscience.org/library/papers/32636848PubMed
28,063,478Developmental expression of B cell molecules in equine lymphoid tissues.Vet Immunol Immunopathol2017https://conductscience.org/library/papers/28063478PubMed
26,577,994Bone marrow fat and the decline of B lymphopoiesis in rabbits.Dev Comp Immunol2016https://conductscience.org/library/papers/26577994PubMed
21,251,012B cell receptor editing in tolerance and autoimmunity.Ann N Y Acad Sci2011https://conductscience.org/library/papers/21251012PubMed
8,096,497Structure and expression of a nonpolymorphic rabbit class II gene with homology to HLA-DOB.Immunogenetics1993https://conductscience.org/library/papers/8096497PubMed
6,815,220Immunoglobulin isotype expression of normal pre-B cells as determined by immunofluorescence.J Clin Immunol1982https://conductscience.org/library/papers/6815220PubMed
6,813,678Biosynthesis and structure of membrane and secretory immunoglobulins.Mol Cell Biochem1982https://conductscience.org/library/papers/6813678PubMed
6,807,841Expression of kappa chain allotypes at the cell surface and in serum immunoglobulins of normal and allotype-suppressed heterozygous rabbits.Immunology1982https://conductscience.org/library/papers/6807841PubMed
6,801,081Pre-B cells; normal and abnormal development.J Clin Immunol1981https://conductscience.org/library/papers/6801081PubMed
6,610,515Development of pre-B and B lymphocytes in the human fetus.Clin Exp Immunol1984https://conductscience.org/library/papers/6610515PubMed
313,015Neoplasias and B-cell precursors.Nature1979https://conductscience.org/library/papers/313015PubMed
92,518Studies on the clonal origin of multiple myeloma. Use of individually specific (idiotype) antibodies to trace the oncogenic event to its earliest point of expression in B-cell differentiation.J Exp Med1979https://conductscience.org/library/papers/92518PubMed

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

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Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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