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Paper · 105355

DNA clones containing mouse immunoglobulin kappa chain genes isolated by in vitro packaging into phage lambda coats.

Lenhard-Schuller R and 4 others. Proc Natl Acad Sci U S A, 1978. Cited by 97 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. DNA clones containing mouse immunoglobulin kappa chain genes isolated by in vitro packaging into phage lambda coats. Papers, record 105355. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/105355

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
DNA clones containing mouse immunoglobulin kappa chain genes isolated by in vitro packaging into phage lambda coats.
PubMed
Journal
Proc Natl Acad Sci U S A
PubMed
Year
1978
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
97
iCite
Relative citation ratio, by iCite
1.95
iCite
Revised in PubMed
2019-05-01
PubMed

Authors5

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Lenhard-Schuller RR
2Hohn BB
3Brack CC
4Hirama MM
5Tonegawa SS

Source PubMed

Topics12

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
ColiphagesMajor topic
DNA, RecombinantMajor topic
Immunoglobulin Light ChainsMajor topic
Immunoglobulin kappa-ChainsMajor topic
Animals
Embryo, Mammalian
Genes
Immunoglobulin Constant Regions
Immunoglobulin Variable Region
Methods
Mice
Myeloma Proteins

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References17

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
11,103,146In vitro construction of bacteriophage lambda carrying segments of the Escherichia coli chromosome: selection of hybrids containing the gene for DNA ligase.Proc Natl Acad Sci U S A1975https://conductscience.org/library/papers/1103146PubMed
21,195,397Detection of specific sequences among DNA fragments separated by gel electrophoresis.J Mol Biol1975https://conductscience.org/library/papers/1195397PubMed
3322,278EK2 derivatives of bacteriophage lambda useful in the cloning of DNA from higher organisms: the lambdagtWES system.Science1977https://conductscience.org/library/papers/322278PubMed
4322,279Screening lambdagt recombinant clones by hybridization to single plaques in situ.Science1977https://conductscience.org/library/papers/322279PubMed
5338,419In vitro packaging of a lambda Dam vector containing EcoRI DNA fragments of Escherichia coli and phage P1.Gene1977https://conductscience.org/library/papers/338419PubMed
6408,080Genetic control of antibody variable regions.Cold Spring Harb Symp Quant Biol1977https://conductscience.org/library/papers/408080PubMed
7408,084Somatic changes in the content and context of immunoglobulin genes.Cold Spring Harb Symp Quant Biol1977https://conductscience.org/library/papers/408084PubMed
8408,266Dynamics of immunoglobulin genes.Immunol Rev1977https://conductscience.org/library/papers/408266PubMed
9410,021Cloning of an immunoglobulin variable region gene from mouse embryo.Proc Natl Acad Sci U S A1977https://conductscience.org/library/papers/410021PubMed
10414,223Variable and constant parts of the immunoglobulin light chain gene of a mouse myeloma cell are 1250 nontranslated bases apart.Proc Natl Acad Sci U S A1977https://conductscience.org/library/papers/414223PubMed

Cited by38

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 97 citations.

PMIDTitleJournalYearIn PapersSource
7,249,397Interaction of HLA and Gm in autoimmune chronic active hepatitis.Clin Exp Immunol1981https://conductscience.org/library/papers/7249397PubMed
6,804,947Single amino acid substitution altering antigen-binding specificity.Proc Natl Acad Sci U S A1982https://conductscience.org/library/papers/6804947PubMed
6,801,628Transcriptional regulation of immunoglobulin V genes.Nucleic Acids Res1981https://conductscience.org/library/papers/6801628PubMed
6,798,155Organization, structure, and assembly of immunoglobulin heavy chain diversity DNA segments.J Exp Med1982https://conductscience.org/library/papers/6798155PubMed
6,787,590Sequences of the joining region genes for immunoglobulin heavy chains and their role in generation of antibody diversity.Proc Natl Acad Sci U S A1981https://conductscience.org/library/papers/6787590PubMed
6,777,777Immunoglobulin V/J recombination is accompanied by deletion of joining site and variable region segments.Proc Natl Acad Sci U S A1980https://conductscience.org/library/papers/6777777PubMed
6,776,532Somatic rearrangements forming active immunoglobulin mu genes in B and T lymphoid cell lines.Proc Natl Acad Sci U S A1980https://conductscience.org/library/papers/6776532PubMed
6,772,972RNA splicing generates a variant light chain from an aberrantly rearranged kappa gene.Nature1980https://conductscience.org/library/papers/6772972PubMed
6,772,734Evidence indicating independent assortment of framework and complementarity-determining segments of the variable regions of rabbit light chains. Delineation of a possible J minigene.J Exp Med1980https://conductscience.org/library/papers/6772734PubMed
6,771,761Expression of the immunoglobulin C mu gene in mouse T and B lymphoid and myeloid cell lines.Proc Natl Acad Sci U S A1980https://conductscience.org/library/papers/6771761PubMed

1 to 10 of 38

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Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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