Paper · 10848643
Calorie restriction increases insulin-stimulated tyrosine phosphorylation of insulin receptor and insulin receptor substrate-1 in rat skeletal muscle.
Dean DJ and 1 other. Acta Physiol Scand, 2000. Cited by 30 papers, by iCite.
11 sourcespapers-2026-11-12-0.1.0
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ConductScience Library. Calorie restriction increases insulin-stimulated tyrosine phosphorylation of insulin receptor and insulin receptor substrate-1 in rat skeletal muscle. Papers, record 10848643. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/10848643
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Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
- Title
- Calorie restriction increases insulin-stimulated tyrosine phosphorylation of insulin receptor and insulin receptor substrate-1 in rat skeletal muscle.
- PubMed
Topics20
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Food Deprivation | Major topic |
| Hypoglycemic Agents | Major topic |
| Insulin | Major topic |
| Muscle, Skeletal | Major topic |
| Phosphoproteins | Major topic |
| Receptor, Insulin | Major topic |
| Animals | |
| Body Weight | |
| Energy Intake | |
| Enzyme Activation | |
| Glucose | |
| Insulin Receptor Substrate Proteins | |
| Male | |
| Phosphatidylinositol 3-Kinases | |
| Phosphorylation | |
| Protein Binding | |
| Rats | |
| Rats, Inbred F344 | |
| Signal Transduction | |
| Tyrosine |
Source PubMed
Grants2
Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.
| Grant, as the record writes it | Agency | Country | NIH project | Stated by | Source |
|---|---|---|---|---|---|
| AG-10026 | NIA NIH HHS | United States | R01AG010026 | PubMed and NIH | NIH RePORTER |
| R29AG010026 | NIH | NIH RePORTER |
Trials0
The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.
None in this release.
Comments and corrections0
PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.
None in this release.
References0
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
None in this release.
Cited by11
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 30 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 42,225,590 | Untargeted metabolomics reveals effects of calorie restriction on skeletal muscle in older female and male rats. | J Gerontol A Biol Sci Med Sci | 2026 | https://conductscience.org/library/papers/42225590 | PubMed |
| 27,289,530 | Caloric Restriction Normalizes Obesity-Induced Alterations on Regulators of Skeletal Muscle Growth Signaling. | Lipids | 2016 | https://conductscience.org/library/papers/27289530 | PubMed |
| 23,755,179 | Heterogeneous effects of calorie restriction on in vivo glucose uptake and insulin signaling of individual rat skeletal muscles. | PLoS One | 2014 | https://conductscience.org/library/papers/23755179 | PubMed |
| 23,115,120 | Greater insulin-mediated Akt phosphorylation concomitant with heterogeneous effects on phosphorylation of Akt substrates in soleus of calorie-restricted rats. | Am J Physiol Regul Integr Comp Physiol | 2012 | https://conductscience.org/library/papers/23115120 | PubMed |
| 22,701,721 | Tissue-specific responses of IGF-1/insulin and mTOR signaling in calorie restricted rats. | PLoS One | 2012 | https://conductscience.org/library/papers/22701721 | PubMed |
| 22,454,372 | Calorie restriction enhances insulin-stimulated glucose uptake and Akt phosphorylation in both fast-twitch and slow-twitch skeletal muscle of 24-month-old rats. | J Gerontol A Biol Sci Med Sci | 2012 | https://conductscience.org/library/papers/22454372 | PubMed |
| 21,985,785 | Sirt1 enhances skeletal muscle insulin sensitivity in mice during caloric restriction. | J Clin Invest | 2011 | https://conductscience.org/library/papers/21985785 | PubMed |
| 21,386,065 | Mechanisms for increased insulin-stimulated Akt phosphorylation and glucose uptake in fast- and slow-twitch skeletal muscles of calorie-restricted rats. | Am J Physiol Endocrinol Metab | 2011 | https://conductscience.org/library/papers/21386065 | PubMed |
| 21,140,129 | Improved cardiac metabolism and activation of the RISK pathway contributes to improved post-ischemic recovery in calorie restricted mice. | J Mol Med (Berl) | 2011 | https://conductscience.org/library/papers/21140129 | PubMed |
| 19,240,254 | Downregulation of Grb2 contributes to the insulin-sensitizing effect of calorie restriction. | Am J Physiol Endocrinol Metab | 2009 | https://conductscience.org/library/papers/19240254 | PubMed |
1 to 10 of 11
See all 11 cited byGenes0
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None in this release.
Drugs0
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None in this release.
Data0
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None in this release.
Data dates
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- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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