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Paper · 11427716

Neurotensin-deficient mice show altered responses to antipsychotic drugs.

Dobner PR and 4 others. Proc Natl Acad Sci U S A, 2001. Cited by 44 papers, by iCite.

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ConductScience Library. Neurotensin-deficient mice show altered responses to antipsychotic drugs. Papers, record 11427716. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/11427716

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Neurotensin-deficient mice show altered responses to antipsychotic drugs.
PubMed
Journal
Proc Natl Acad Sci U S A
PubMed
Year
2001
PubMed
Publication types
Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
44
iCite
Relative citation ratio, by iCite
1.08
iCite
Revised in PubMed
2018-11-13
PubMed

Authors5

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Dobner PRP R
2Fadel JJ
3Deitemeyer NN
4Carraway RER E
5Deutch AYA Y

Source PubMed

Topics9

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Antipsychotic AgentsMajor topic
CatalepsyMajor topic
HaloperidolMajor topic
NeurotensinMajor topic
Animals
Gene Deletion
Gene Targeting
Mice
Molecular Sequence Data

Source PubMed

Grants4

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated bySource
R01 MH057995NIMH NIH HHSUnited StatesR01MH057995PubMed and NIHNIH RePORTER
HL 33307NHLBI NIH HHSUnited StatesR01HL033307PubMed and NIHNIH RePORTER
MH 57995NIMH NIH HHSUnited StatesR01MH057995PubMed and NIHNIH RePORTER
R23HL033307NIHNIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References56

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
13,154,507Reduced CSF neurotensin concentration in drug-free schizophrenic patients.Schizophr Res1988https://conductscience.org/library/papers/3154507PubMed
29,851,594Neurotensin is an antagonist of the human neurotensin NT2 receptor expressed in Chinese hamster ovary cells.Eur J Pharmacol1998https://conductscience.org/library/papers/9851594PubMed
31,361,115The current status of neurotensin-dopamine interactions. Issues and speculations.Ann N Y Acad Sci1992https://conductscience.org/library/papers/1361115PubMed
410,390,649Neurotensin and neurotensin receptors.Trends Pharmacol Sci1999https://conductscience.org/library/papers/10390649PubMed
51,674,882Mechanisms of action of atypical antipsychotic drugs. Implications for novel therapeutic strategies for schizophrenia.Schizophr Res1991https://conductscience.org/library/papers/1674882PubMed
67,517,175CSF concentrations of neurotensin in schizophrenia: an investigation of clinical and biochemical correlates.Schizophr Res1994https://conductscience.org/library/papers/7517175PubMed
710,435,199Does neurotensin mediate the effects of antipsychotic drugs?Biol Psychiatry1999https://conductscience.org/library/papers/10435199PubMed
88,876,464Cellular distribution of neurotensin receptors in rat brain: immunohistochemical study using an antipeptide antibody against the cloned high affinity receptor.J Comp Neurol1996https://conductscience.org/library/papers/8876464PubMed
97,804,603c-fos antisense oligonucleotide specifically attenuates haloperidol-induced increases in neurotensin/neuromedin N mRNA expression in rat dorsal striatum.Mol Cell Neurosci1994https://conductscience.org/library/papers/7804603PubMed
102,857,492Complete coding sequence of rat tyrosine hydroxylase mRNA.Proc Natl Acad Sci U S A1985https://conductscience.org/library/papers/2857492PubMed

1 to 10 of 56

See all 56 references

Cited by16

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 44 citations.

PMIDTitleJournalYearIn PapersSource
39,648,233Decreased neurotensin induces ovulatory dysfunction via the NTSR1/ERK/EGR1 axis in polycystic ovary syndrome.Front Med2025https://conductscience.org/library/papers/39648233PubMed
33,811,694Neurotensin differentially regulates bile acid metabolism and intestinal FXR-bile acid transporter axis in response to nutrient abundance.FASEB J2021https://conductscience.org/library/papers/33811694PubMed
27,193,687An obligatory role for neurotensin in high-fat-diet-induced obesity.Nature2016https://conductscience.org/library/papers/27193687PubMed
25,449,842Striatal dopamine receptor plasticity in neurotensin deficient mice.Behav Brain Res2015https://conductscience.org/library/papers/25449842PubMed
25,433,325Repeated effects of the neurotensin receptor agonist PD149163 in three animal tests of antipsychotic activity: assessing for tolerance and cross-tolerance to clozapine.Pharmacol Biochem Behav2015https://conductscience.org/library/papers/25433325PubMed
24,416,154Endogenous CNS expression of neurotensin and neurotensin receptors is altered during the postpartum period in outbred mice.PLoS One2014https://conductscience.org/library/papers/24416154PubMed
21,720,755Effects of neurotensin gene knockout in mice on the behavioral effects of cocaine.Psychopharmacology (Berl)2012https://conductscience.org/library/papers/21720755PubMed
20,211,191Hyperactivity of the dopaminergic system in NTS1 and NTS2 null mice.Neuropharmacology2010https://conductscience.org/library/papers/20211191PubMed
20,193,696
Effect of amphetamine on extracellular concentrations of amino acids in striatum in neurotensin subtype 1 and 2 receptor null mice: a possible interaction between neurotensin receptors and amino acid systems for study of schizophrenia.
Neuropharmacology2010https://conductscience.org/library/papers/20193696PubMed
19,443,690Neurotensin induces IL-6 secretion in mouse preadipocytes and adipose tissues during 2,4,6,-trinitrobenzensulphonic acid-induced colitis.Proc Natl Acad Sci U S A2009https://conductscience.org/library/papers/19443690PubMed

1 to 10 of 16

See all 16 cited by

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data1

The data bank entries PubMed's record names. Trial numbers are under Trials.

Data bankAccession
GENBANKAF348489

Source GENBANK

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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