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Paper · 39648233

Decreased neurotensin induces ovulatory dysfunction via the NTSR1/ERK/EGR1 axis in polycystic ovary syndrome.

Wang D and 7 others. Front Med, 2025. Cited by 3 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Decreased neurotensin induces ovulatory dysfunction via the NTSR1/ERK/EGR1 axis in polycystic ovary syndrome. Papers, record 39648233. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/39648233

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Decreased neurotensin induces ovulatory dysfunction via the NTSR1/ERK/EGR1 axis in polycystic ovary syndrome.
PubMed
Journal
Front Med
PubMed
Year
2025
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
3
iCite
Revised in PubMed
2026-11-02
PubMed

Authors8

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Wang DDongshuang
2Zhang MMeiling
3Wang WSWang-Sheng
4Chu WWeiwei
5Zhai JJunyu
6Sun YYun
7Chen ZJZi-Jiang
8Du YYanzhi

Source PubMed

Topics16

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Polycystic Ovary SyndromeMajor topic
NeurotensinMajor topic
Receptors, NeurotensinMajor topic
OvulationMajor topic
Female
Animals
Mice
Humans
Granulosa Cells
Adult
Oocytes
MAP Kinase Signaling System
Signal Transduction
Follicular Fluid
Disease Models, Animal
Gonadotropin-Releasing Hormone

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References73

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
12,912,701Evidence that neurotensin participates in the central regulation of the preovulatory surge of luteinizing hormone in the rat.Endocrinology1989https://conductscience.org/library/papers/2912701PubMed
229,602,523Endocrine, Paracrine, and Autocrine Signaling Pathways That Regulate Ovulation.Trends Endocrinol Metab2018https://conductscience.org/library/papers/29602523PubMed
311,427,716Neurotensin-deficient mice show altered responses to antipsychotic drugs.Proc Natl Acad Sci U S A2001https://conductscience.org/library/papers/11427716PubMed
430,962,551Genetic paradox explained by nonsense.Nature2019https://conductscience.org/library/papers/30962551PubMed
57,962,697Estrogen-inducible neurotensin immunoreactivity in the preoptic area of the female rat.J Comp Neurol1994https://conductscience.org/library/papers/7962697PubMed
69,440,815Multiple pituitary and ovarian defects in Krox-24 (NGFI-A, Egr-1)-targeted mice.Mol Endocrinol1998https://conductscience.org/library/papers/9440815PubMed
727,193,687An obligatory role for neurotensin in high-fat-diet-induced obesity.Nature2016https://conductscience.org/library/papers/27193687PubMed
836,933,790Increased meal-induced neurotensin response predicts successful maintenance of weight loss - Data from a randomized controlled trial.Metabolism2023https://conductscience.org/library/papers/36933790PubMed
930,691,623Mitochondrial unfolded protein response: a stress response with implications for fertility and reproductive aging.Fertil Steril2019https://conductscience.org/library/papers/30691623PubMed
1019,861,584Interactions between neurotensin and GnRH neurons in the positive feedback control of GnRH/LH secretion in the mouse.Am J Physiol Endocrinol Metab2010https://conductscience.org/library/papers/19861584PubMed

1 to 10 of 73

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Cited by3

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 3 citations.

PMIDTitleJournalYearIn PapersSource
41,783,728Expression of TGFB1 and ERK in cumulus cells: Implications for oocyte maturation in women with polycystic ovary syndrome: A cross-sectional study.Int J Reprod Biomed2025https://conductscience.org/library/papers/41783728PubMed
41,014,186Neurotensin drives theca cell migration during ovulation in primates†.Biol Reprod2026https://conductscience.org/library/papers/41014186PubMed
40,471,330Neurotensin modulates the female reproductive system via extracellular signal-regulated kinase 1/2 signaling pathway: an in vivo and in silico study in mice.Mol Biol Rep2025https://conductscience.org/library/papers/40471330PubMed

Genes4

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
EGR11,958PubTator's text mininghttps://conductscience.org/library/genes/1958NCBI Gene
MAPK15,594PubTator's text mininghttps://conductscience.org/library/genes/5594NCBI Gene
NTS4,922PubTator's text mininghttps://conductscience.org/library/genes/4922NCBI Gene
NTSR14,923PubTator's text mininghttps://conductscience.org/library/genes/4923NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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