Paper · 1164592

An analysis of the depressor responses to histamine in the cat and dog: involvement of both H1- and H2-receptors.

Black JW and 2 others. Br J Pharmacol, 1975. Cited by 121 papers, by iCite.

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ConductScience Library. An analysis of the depressor responses to histamine in the cat and dog: involvement of both H1- and H2-receptors. Papers, record 1164592. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/1164592

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: An analysis of the depressor responses to histamine in the cat and dog: involvement of both H1- and H2-receptors.; PubMed
Journal: Br J Pharmacol; PubMed
Year: 1975; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/1164592/; PubMed
DOI: https://doi.org/10.1111/j.1476-5381.1975.tb07571.x; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC1666465/; PubMed
The journal: https://conductscience.org/library/journal-index/7502536; PubMed
Citations, by iCite: 121; iCite
Relative citation ratio, by iCite: 6.56; iCite
Revised in PubMed: 2019-05-09; PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Black JW	J W
2	Owen DA	D A
3	Parsons ME	M E

Source PubMed

Topics11

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Blood Pressure	Major topic
Histamine	Major topic
Animals
Cats
Depression, Chemical
Dose-Response Relationship, Drug
Female
Male
Metiamide
Pyrilamine
Receptors, Drug

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References3

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
3	4,150,324	Metiamide--an orally active histamine H2-receptor antagonist.	Agents Actions	1973	https://conductscience.org/library/papers/4150324	PubMed
4	4,401,751	Definition and antagonism of histamine H 2 -receptors.	Nature	1972	https://conductscience.org/library/papers/4401751	PubMed
5	4,155,327	Proceedings: Histamine receptors in the cardiovascular system of the cat.	Br J Pharmacol	1974	https://conductscience.org/library/papers/4155327	PubMed

Cited by43

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 121 citations.

PMID	Title	Journal	Year	In Papers	Source
34,282,171	Ipsilateral somatic nerves mediate histamine-induced vasosensory reflex responses involving perivascular afferents in rat models.	Sci Rep	2021	https://conductscience.org/library/papers/34282171	PubMed
28,695,272	Cardiovascular effects of histamine in three widely diverse species of reptiles.	J Comp Physiol B	2018	https://conductscience.org/library/papers/28695272	PubMed
27,609,040	Functional in vitro tension measurements of fascial tissue - a novel modified superfusion approach.	J Musculoskelet Neuronal Interact	2016	https://conductscience.org/library/papers/27609040	PubMed
24,858,599	Modulation of tissue inflammatory response by histamine receptors in scorpion envenomation pathogenesis: involvement of H4 receptor.	Inflammation	2014	https://conductscience.org/library/papers/24858599	PubMed
23,488,545	Histamine-induced vasodilatation in the human forearm vasculature.	Br J Clin Pharmacol	2013	https://conductscience.org/library/papers/23488545	PubMed
12,757,165	Acid-induced mesenteric hyperemia in rats: role of CGRP, substance P, prostaglandin, adenosine, and histamine.	Dig Dis Sci	2003	https://conductscience.org/library/papers/12757165	PubMed
9,575,302	Mediation by 5_hydroxytryptamine of the femoral vasoconstriction induced by acid challenge of the rat gastric mucosa.	J Physiol	1998	https://conductscience.org/library/papers/9575302	PubMed
8,597,878	Flush induced by fluoroquinolones in canine skin.	Inflamm Res	1995	https://conductscience.org/library/papers/8597878	PubMed
7,386,301	Identification of histamine H1- and H-2-receptors by means of mepyramine, cimetidine and theophylline in the cardiovascular system of the dog.	Agents Actions	1980	https://conductscience.org/library/papers/7386301	PubMed
7,378,641	Pharmacological analysis of salivary and blood flow responses to histamine of the submandibular gland of the dog.	Br J Pharmacol	1980	https://conductscience.org/library/papers/7378641	PubMed

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Genes0

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None in this release.

Drugs0

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None in this release.

Data0

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None in this release.

Data dates

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PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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