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Paper · 11680452

Is the placebo powerless?

Spiegel D and 2 others. N Engl J Med, 2001. Cited by 32 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Is the placebo powerless? Papers, record 11680452. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/11680452

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Is the placebo powerless?
PubMed
Journal
N Engl J Med
PubMed
Year
2001
PubMed
Publication types
Comment, Letter
PubMed
Citations, by iCite
32
iCite
Relative citation ratio, by iCite
0.96
iCite
Revised in PubMed
2011-11-17
PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Spiegel DD
2Kraemer HH
3Carlson RWR W

Source PubMed

Topics7

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Placebo EffectMajor topic
Humans
Meta-Analysis as Topic
Pain Management
Placebos
Randomized Controlled Trials as Topic
Treatment Outcome

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections1

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

KindPMIDTitleIn Papers
Comment on11,372,012Is the placebo powerless? An analysis of clinical trials comparing placebo with no treatment.https://conductscience.org/library/papers/11372012

Source PubMed

References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

None in this release.

Cited by10

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 32 citations.

PMIDTitleJournalYearIn PapersSource
37,848,293Placebo and nocebo effects and mechanisms associated with pharmacological interventions: an umbrella review.BMJ Open2023https://conductscience.org/library/papers/37848293PubMed
34,716,400Differential power of placebo across major psychiatric disorders: a preliminary meta-analysis and machine learning study.Sci Rep2021https://conductscience.org/library/papers/34716400PubMed
23,690,944Are treatments more effective than placebos? A systematic review and meta-analysis.PLoS One2013https://conductscience.org/library/papers/23690944PubMed
22,110,329Psychological interventions in the management of common skin conditions.Psychol Res Behav Manag2010https://conductscience.org/library/papers/22110329PubMed
21,727,941The placebo effect in overactive bladder syndrome.Nat Rev Urol2011https://conductscience.org/library/papers/21727941PubMed
21,576,148Placebo interventions, placebo effects and clinical practice.Philos Trans R Soc Lond B Biol Sci2011https://conductscience.org/library/papers/21576148PubMed
19,148,323Placebos in medicine: knowledge, beliefs, and patterns of use.Mcgill J Med2008https://conductscience.org/library/papers/19148323PubMed
18,390,494What is the placebo worth?BMJ2008https://conductscience.org/library/papers/18390494PubMed
15,814,066Trick or treat: the effect of placebo on the power of pharmacogenetic association studies.Hum Genomics2005https://conductscience.org/library/papers/15814066PubMed
15,499,085Placebos in practice.BMJ2004https://conductscience.org/library/papers/15499085PubMed

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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