Paper · 129707

Differential function of major histocompatibility complex antigens in T-lymphocyte activation.

Bach FH and 2 others. Nature, 1976. Cited by 563 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Differential function of major histocompatibility complex antigens in T-lymphocyte activation. Papers, record 129707. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/129707

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Differential function of major histocompatibility complex antigens in T-lymphocyte activation.; PubMed
Journal: Nature; PubMed
Year: 1976; PubMed
Publication types: Journal Article, Research Support, U.S. Gov't, P.H.S., Review; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/129707/; PubMed
DOI: https://doi.org/10.1038/259273a0; PubMed
The journal: https://conductscience.org/library/journal-index/0410462; PubMed
Citations, by iCite: 563; iCite
Relative citation ratio, by iCite: 13.4; iCite
Revised in PubMed: 2019-06-17; PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Bach FH	F H
2	Bach ML	M L
3	Sondel PM	P M

Source PubMed

Topics13

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Genes	Major topic
Histocompatibility Antigens	Major topic
Lymphocyte Activation	Major topic
T-Lymphocytes	Major topic
Animals
Cytotoxicity Tests, Immunologic
HLA Antigens
Humans
Isoantigens
Lymphocyte Culture Test, Mixed
Mice
Mice, Inbred Strains
Models, Biological

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

None in this release.

Cited by94

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 563 citations.

PMID	Title	Journal	Year	In Papers	Source
37,674,842	Identification of CCDC115 as an adverse prognostic biomarker in liver cancer based on bioinformatics and experimental analyses.	Heliyon	2023	https://conductscience.org/library/papers/37674842	PubMed
36,965,699	Cellular reprogramming of fibroblasts in heart regeneration.	J Mol Cell Cardiol	2023	https://conductscience.org/library/papers/36965699	PubMed
35,529,847	Transplant Tolerance, Not Only Clonal Deletion.	Front Immunol	2022	https://conductscience.org/library/papers/35529847	PubMed
34,944,652	iPSC Therapy for Myocardial Infarction in Large Animal Models: Land of Hope and Dreams.	Biomedicines	2021	https://conductscience.org/library/papers/34944652	PubMed
34,897,277	T cell receptor (TCR) signaling in health and disease.	Signal Transduct Target Ther	2021	https://conductscience.org/library/papers/34897277	PubMed
33,178,706	Coreceptors and TCR Signaling - the Strong and the Weak of It.	Front Cell Dev Biol	2020	https://conductscience.org/library/papers/33178706	PubMed
28,255,564	Endothelial Cells in Antibody-Mediated Rejection of Kidney Transplantation: Pathogenesis Mechanisms and Therapeutic Implications.	J Immunol Res	2017	https://conductscience.org/library/papers/28255564	PubMed
27,723,741	Allogeneic transplantation of iPS cell-derived cardiomyocytes regenerates primate hearts.	Nature	2016	https://conductscience.org/library/papers/27723741	PubMed
23,876,775	The class III histone deacetylase sirtuin 1 in immune suppression and its therapeutic potential in rheumatoid arthritis.	J Genet Genomics	2013	https://conductscience.org/library/papers/23876775	PubMed
21,302,058	Strong and weak immune responses across the same major histocompatibility barrier in rats.	Immunogenetics	1978	https://conductscience.org/library/papers/21302058	PubMed

1 to 10 of 94

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Genes1

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes
HLA-C	3,107	PubTator's text mining	https://conductscience.org/library/genes/3107

Source NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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