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Paper165484

Plasminogen-independent fibrinolysis by proteases produced by transformed chick embryo fibroblasts.

Chen LB and 1 other. Proc Natl Acad Sci U S A, 1975. Cited by 52 papers, by iCite.

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ConductScience Library. Plasminogen-independent fibrinolysis by proteases produced by transformed chick embryo fibroblasts. Papers, record 165484. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/165484

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Plasminogen-independent fibrinolysis by proteases produced by transformed chick embryo fibroblasts.
PubMed
Journal
Proc Natl Acad Sci U S A
PubMed
Year
1975
PubMed
Publication types
Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
52
iCite
Relative citation ratio, by iCite
1.65
iCite
Revised in PubMed
2019-05-01
PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Chen LBL B
2Buchanan JMJ M

Source PubMed

Topics16

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Cell Transformation, NeoplasticMajor topic
FibrinolysisMajor topic
Peptide HydrolasesMajor topic
PlasminogenMajor topic
Animals
Avian Sarcoma Viruses
Cell Division
Cell Line
Chick Embryo
Deoxyglucose
Fibrinogen
Fibroblasts
Peptides
Phenotype
Thrombin
Trypsin

Source PubMed

References17

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
11,054,489Mitogenic activity of blood components. I. Thrombin and prothrombin.Proc Natl Acad Sci U S A1975https://conductscience.org/library/papers/1054489PubMed
213,974,222Purification of human plasminogen and plasmin by gel filtration on Sephadex and chromatography on diethylaminoethyl-Sephadex.J Biol Chem1963https://conductscience.org/library/papers/13974222PubMed
44,185,494An enzymic method for the trace iodination of immunoglobulins and other proteins.Biochem J1969https://conductscience.org/library/papers/4185494PubMed
54,268,001The secretion of fibrinolysin by cultured rat ovarian tumor cells.Biochem Biophys Res Commun1973https://conductscience.org/library/papers/4268001PubMed
64,330,938Temperature-dependent alterations in sugar transport in cells infected by a temperature-sensitive mutant of Rous sarcoma virus.Proc Natl Acad Sci U S A1971https://conductscience.org/library/papers/4330938PubMed
74,347,290An enzymatic function associated with transformation of fibroblasts by oncogenic viruses. I. Chick embryo fibroblast cultures transformed by avian RNA tumor viruses.J Exp Med1973https://conductscience.org/library/papers/4347290PubMed
84,355,423Fibrinolysis associated with oncogenic transformation. Requirement of plasminogen for correlated changes in cellular morphology, colony formation in agar, and cell migration.J Exp Med1973https://conductscience.org/library/papers/4355423PubMed
94,363,605Purification and characterization of a cellular fibrinolytic factor associated with oncogenic transformation: the plasminogen activator from SV-40-transformed hamster cells.Biochim Biophys Acta1974https://conductscience.org/library/papers/4363605PubMed
104,368,726Fibrinolysis associated with oncogenic transformation. Morphological correlates.J Biol Chem1974https://conductscience.org/library/papers/4368726PubMed
114,368,727Fibrinolysis associated with oncogenic transformation. Partial purification and characterization of the cell factor, a plasminogen activator.J Biol Chem1974https://conductscience.org/library/papers/4368727PubMed
124,369,021Plasminogen, the serum proenzyme activated by factors from cells transformed by oncogenic viruses.J Biol Chem1974https://conductscience.org/library/papers/4369021PubMed
134,370,416Suppression of fibrinolysin T activity fails to restore density-dependent growth inhibition to SV3T3 cells.Nature1974https://conductscience.org/library/papers/4370416PubMed
144,376,055Increased protease levels in transformed cells: a casein overlay assay for the detection of plasminogen activator production.Cell1974https://conductscience.org/library/papers/4376055PubMed
154,842,906Fibrinolytic activity associated with human neuroblastoma cells.Exp Cell Res1974https://conductscience.org/library/papers/4842906PubMed
165,066,246Detection of caseinolytic and fibrinolytic activities of BHK-21 cell strains.Exp Cell Res1972https://conductscience.org/library/papers/5066246PubMed
175,475,635Plasminogen: purification from human plasma by affinity chromatography.Science1970https://conductscience.org/library/papers/5475635PubMed
186,070,849Bovine thrombin. Purification and certain properties.J Biol Chem1967https://conductscience.org/library/papers/6070849PubMed

Cited by12

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 52 citations.

PMIDTitleJournalYearIn PapersSource
6,988,694Fibronectin: a review of its structure and biological activity.Mol Cell Biochem1980https://conductscience.org/library/papers/6988694PubMed
6,325,472Expression of transformation-associated protease(s) that degrade fibronectin at cell contact sites.J Cell Biol1984https://conductscience.org/library/papers/6325472PubMed
6,199,661Diverse mitogenic agents induce the phosphorylation of two related 42,000-dalton proteins on tyrosine in quiescent chick cells.Mol Cell Biol1984https://conductscience.org/library/papers/6199661PubMed
2,172,980A 170-kDa membrane-bound protease is associated with the expression of invasiveness by human malignant melanoma cells.Proc Natl Acad Sci U S A1990https://conductscience.org/library/papers/2172980PubMed
1,068,469Correlation between tumor induction and the large external transformation sensitive protein on the cell surface.Proc Natl Acad Sci U S A1976https://conductscience.org/library/papers/1068469PubMed
351,614Transformation-dependent secretion of a low molecular weight protein by murine fibroblasts.Proc Natl Acad Sci U S A1978https://conductscience.org/library/papers/351614PubMed
202,848Phenotypes of Rous sarcoma virus-transformed fibroblasts: an argument for a multifunctional Src gene product.Med Microbiol Immunol1977https://conductscience.org/library/papers/202848PubMed
191,817Binding and internalization of thrombin by normal and transformed chick cells.Proc Natl Acad Sci U S A1977https://conductscience.org/library/papers/191817PubMed
191,634Distinguishable transformation-defective phenotypes among temperature-sensitive mutants of Rous sarcoma virus.J Virol1977https://conductscience.org/library/papers/191634PubMed
185,621Rous-sarcoma-virus-transformed fibroblasts having low levels of plasminogen activator.Proc Natl Acad Sci U S A1976https://conductscience.org/library/papers/185621PubMed
171,654Surface ruffles as markers for studies of cell transformation by Rous sarcoma virus.Proc Natl Acad Sci U S A1975https://conductscience.org/library/papers/171654PubMed
9,031Human skin proteases. Fractionation of psoriasis scale proteases and separation of a plasminogen activator and a histone hydrolysing protease.Arch Dermatol Res (1975)1976https://conductscience.org/library/papers/9031PubMed

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

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  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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