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Paper6325472

Expression of transformation-associated protease(s) that degrade fibronectin at cell contact sites.

Chen WT and 3 others. J Cell Biol, 1984. Cited by 170 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Expression of transformation-associated protease(s) that degrade fibronectin at cell contact sites. Papers, record 6325472. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/6325472

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Expression of transformation-associated protease(s) that degrade fibronectin at cell contact sites.
PubMed
Journal
J Cell Biol
PubMed
Year
1984
PubMed
Publication types
Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
170
iCite
Relative citation ratio, by iCite
3.87
iCite
Revised in PubMed
2019-05-08
PubMed

Authors4

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Chen WTW T
2Olden KK
3Bernard BAB A
4Chu FFF F

Source PubMed

Topics15

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Cell Transformation, ViralMajor topic
FibronectinsMajor topic
Peptide HydrolasesMajor topic
Animals
Avian Sarcoma Viruses
Cells, Cultured
Chick Embryo
Fibroblasts
Fluorescent Antibody Technique
Gelatin
Histocytochemistry
Kinetics
Mice
Mice, Inbred BALB C
Protease Inhibitors

Source PubMed

Grants3

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated bySource
CA-34494NCI NIH HHSUnited StatesR01CA034494PubMed and NIHNIH RePORTER
GM-29804NIGMS NIH HHSUnited StatesR01GM029804PubMed and NIHNIH RePORTER
HL-31762NHLBI NIH HHSUnited StatesR01HL031762PubMed and NIHNIH RePORTER

References39

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
14,331,732The effects of reciprocal changes in temperature on the transformed state of cells infected with a rous sarcoma virus mutant.Virology1971https://conductscience.org/library/papers/4331732PubMed
24,347,290An enzymatic function associated with transformation of fibroblasts by oncogenic viruses. I. Chick embryo fibroblast cultures transformed by avian RNA tumor viruses.J Exp Med1973https://conductscience.org/library/papers/4347290PubMed
34,361,679Alteration of cell-surface proteins by viral transformation and by proteolysis.Proc Natl Acad Sci U S A1973https://conductscience.org/library/papers/4361679PubMed
4165,484Plasminogen-independent fibrinolysis by proteases produced by transformed chick embryo fibroblasts.Proc Natl Acad Sci U S A1975https://conductscience.org/library/papers/165484PubMed
5167,099Fibroblast surface antigen produced but not retained by virus-transformed human cells.J Exp Med1975https://conductscience.org/library/papers/167099PubMed
6177,979Cell surface protein partially restores morphology, adhesiveness, and contact inhibition of movement to transformed fibroblasts.Proc Natl Acad Sci U S A1976https://conductscience.org/library/papers/177979PubMed
7993,259Association of a protease (plasminogen activator) with a specific membrane fraction isolated from transformed cells.J Cell Biol1976https://conductscience.org/library/papers/993259PubMed
8136,986Relationship between cell surface protease activity and doubling time in various normal and transformed cells.Biochim Biophys Acta1976https://conductscience.org/library/papers/136986PubMed
9189,934Decreased adherence to the substrate in Rous sarcoma virus-transformed chicken embryo fibroblasts.Cell1977https://conductscience.org/library/papers/189934PubMed
10557,370Microfilament bundles and cell shape are related to adhesiveness to substratum and are dissociable from growth control in cultured fibroblasts.Cell1977https://conductscience.org/library/papers/557370PubMed
11862,025In vitro traits of adenovirus-transformed cell lines and their relevance to tumorigenicity in nude mice.Cell1977https://conductscience.org/library/papers/862025PubMed
12326,414Restoration of normal morphology, adhesion and cytoskeleton in transformed cells by addition of a transformation-sensitive surface protein.Cell1977https://conductscience.org/library/papers/326414PubMed
13196,771Mechanism of the decrease in the major cell surface protein of chick embryo fibroblasts after transformation.Cell1977https://conductscience.org/library/papers/196771PubMed
14198,783Levels of translatable mRNAs for cell surface protein, collagen precursors, and two membrane proteins are altered in Rous sarcoma virus-transformed chick embryo fibroblasts.Proc Natl Acad Sci U S A1977https://conductscience.org/library/papers/198783PubMed
15562,674Characterization of a major fibroblast cell surface glycoprotein.Biochemistry1977https://conductscience.org/library/papers/562674PubMed
16357,987Fibronectins--adhesive glycoproteins of cell surface and blood.Nature1978https://conductscience.org/library/papers/357987PubMed
17444,559Proteolytic enzymes in normal and transformed cells.Biochim Biophys Acta1979https://conductscience.org/library/papers/444559PubMed
18222,474Phorbol ester-induced morphological changes in transformed chick fibroblasts: evidence for direct catalytic involvement of plasminogen activator.Cell1979https://conductscience.org/library/papers/222474PubMed
19383,280Production of fibronectin by human epithelial cells in culture.Cancer Res1979https://conductscience.org/library/papers/383280PubMed
206,251,464Adhesion plaques of Rous sarcoma virus-transformed cells contain the src gene product.Proc Natl Acad Sci U S A1980https://conductscience.org/library/papers/6251464PubMed

See all 39 references

Cited by49

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 170 citations.

PMIDTitleJournalYearIn PapersSource
42,715,512A phase field model with stochastic input simulates cellular gradient sensing, morphodynamics, and fidelity of haptotaxis.PLoS Comput Biol2026https://conductscience.org/library/papers/42715512PubMed
41,959,168A phase field model with stochastic input simulates cellular gradient sensing, morphodynamics, and fidelity of haptotaxis.bioRxiv2026https://conductscience.org/library/papers/41959168PubMed
41,461,906Guidance for 3D traction force microscopy today and in the next decade.Nat Methods2026https://conductscience.org/library/papers/41461906PubMed
38,347,328A Model for Membrane Degradation Using a Gelatin Invadopodia Assay.Bull Math Biol2024https://conductscience.org/library/papers/38347328PubMed
24,488,697The matricellular protein CCN5 regulates podosome function via interaction with integrin αvβ 3.J Cell Commun Signal2014https://conductscience.org/library/papers/24488697PubMed
23,873,940Differential Tks5 isoform expression contributes to metastatic invasion of lung adenocarcinoma.Genes Dev2013https://conductscience.org/library/papers/23873940PubMed
22,952,016Quantitative measurement of invadopodia-mediated extracellular matrix proteolysis in single and multicellular contexts.J Vis Exp2012https://conductscience.org/library/papers/22952016PubMed
20,505,783Saracatinib Impairs Head and Neck Squamous Cell Carcinoma Invasion by Disrupting Invadopodia Function.J Cancer Sci Ther2009https://conductscience.org/library/papers/20505783PubMed
20,356,925Dendritic cell podosomes are protrusive and invade the extracellular matrix using metalloproteinase MMP-14.J Cell Sci2010https://conductscience.org/library/papers/20356925PubMed
19,596,797Nck adaptor proteins link Tks5 to invadopodia actin regulation and ECM degradation.J Cell Sci2009https://conductscience.org/library/papers/19596797PubMed
16,830,222Invadopodia: specialized cell structures for cancer invasion.Clin Exp Metastasis2006https://conductscience.org/library/papers/16830222PubMed
12,702,753Cancer cachexia: its correlations and causes.Proc Natl Acad Sci U S A2003https://conductscience.org/library/papers/12702753PubMed
11,585,912Transformation of chicken embryo fibroblasts by v-src uncouples beta1 integrin-mediated outside-in but not inside-out signaling.Mol Cell Biol2001https://conductscience.org/library/papers/11585912PubMed
10,449,748Wiskott-Aldrich syndrome protein regulates podosomes in primary human macrophages.Proc Natl Acad Sci U S A1999https://conductscience.org/library/papers/10449748PubMed
9,872,598Proteolysis of extracellular matrix by invadopodia facilitates human breast cancer cell invasion and is mediated by matrix metalloproteinases.Clin Exp Metastasis1998https://conductscience.org/library/papers/9872598PubMed
8,762,055Phagocytosis and intracellular digestion of collagen, its role in turnover and remodelling.Histochem J1996https://conductscience.org/library/papers/8762055PubMed
8,422,710Adriamycin-induced inhibition of melanoma cell invasion is correlated with decreases in tumor cell motility and increases in focal contact formation.Clin Exp Metastasis1993https://conductscience.org/library/papers/8422710PubMed
8,195,290Interactions of tensin with actin and identification of its three distinct actin-binding domains.J Cell Biol1994https://conductscience.org/library/papers/8195290PubMed
8,143,347Focal adhesion as a signal transduction organelle.Cancer Metastasis Rev1994https://conductscience.org/library/papers/8143347PubMed
7,881,100Membrane proteases as potential diagnostic and therapeutic targets for breast malignancy.Breast Cancer Res Treat1994https://conductscience.org/library/papers/7881100PubMed

See all 49 cited by

Genes2

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
A2M2PubTator's text mininghttps://conductscience.org/library/genes/2NCBI Gene
FN12,335PubTator's text mininghttps://conductscience.org/library/genes/2335NCBI Gene

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

  • Trials
  • Comments and corrections
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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