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Paper · 17510286

Effects of RAS on the genesis of embryonal rhabdomyosarcoma.

Langenau DM and 9 others. Genes Dev, 2007. Cited by 272 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Effects of RAS on the genesis of embryonal rhabdomyosarcoma. Papers, record 17510286. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/17510286

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Effects of RAS on the genesis of embryonal rhabdomyosarcoma.
PubMed
Journal
Genes Dev
PubMed
Year
2007
PubMed
Publication types
Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't
PubMed
Citations, by iCite
272
iCite
Relative citation ratio, by iCite
5.16
iCite
Revised in PubMed
2024-04-17
PubMed

Authors10

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Langenau DMDavid M
2Keefe MDMatthew D
3Storer NYNarie Y
4Guyon JRJeffrey R
5Kutok JLJeffery L
6Le XXiuning
7Goessling WWolfram
8Neuberg DSDonna S
9Kunkel LMLouis M
10Zon LILeonard I

Source PubMed

Topics21

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Gene Expression Regulation, DevelopmentalMajor topic
Genes, rasMajor topic
Rhabdomyosarcoma, EmbryonalMajor topic
ZebrafishMajor topic
Adenosine Deaminase
Animals
Animals, Genetically Modified
Biomarkers, Tumor
Cell Differentiation
Cell Transformation, Neoplastic
Cells, Cultured
DNA-Binding Proteins
Embryo, Nonmammalian
Gene Expression Profiling
Humans
In Situ Hybridization
Kidney
Microinjections
Muscle, Skeletal
Oligonucleotide Array Sequence Analysis
RNA-Binding Proteins

Source PubMed

Grants5

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated bySource
T32 GM007753NIGMS NIH HHSUnited StatesT32GM007753PubMed and NIHNIH RePORTER
R01 CA103846NCI NIH HHSUnited StatesR01CA103846PubMed and NIHNIH RePORTER
P30 HD018655NICHD NIH HHSUnited StatesP30HD018655PubMed and NIHNIH RePORTER
5R01 CA103846-02NCI NIH HHSUnited StatesR01CA103846PubMed and NIHNIH RePORTER
P30HD018655NICHD NIH HHSUnited StatesP30HD018655PubMed and NIHNIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections2

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

KindPMIDTitleIn PapersSource
Erratum in38,631,822Corrigendium: Effects of RAS on the genesis of embryonal rhabdomyosarcoma.https://conductscience.org/library/papers/38631822PubMed
Comment in17,545,462Fishing for the origins of cancer.https://conductscience.org/library/papers/17545462PubMed

References53

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
115,608,639An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysis.Nat Genet2005https://conductscience.org/library/papers/15608639PubMed
215,630,097tp53 mutant zebrafish develop malignant peripheral nerve sheath tumors.Proc Natl Acad Sci U S A2005https://conductscience.org/library/papers/15630097PubMed
315,827,121Cre/lox-regulated transgenic zebrafish model with conditional myc-induced T cell acute lymphoblastic leukemia.Proc Natl Acad Sci U S A2005https://conductscience.org/library/papers/15827121PubMed
415,962,335Variations in gene expression among different types of human skeletal muscle.Muscle Nerve2005https://conductscience.org/library/papers/15962335PubMed
516,199,517Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.Proc Natl Acad Sci U S A2005https://conductscience.org/library/papers/16199517PubMed
616,243,526Stem cells in postnatal myogenesis: molecular mechanisms of satellite cell quiescence, activation and replenishment.Trends Cell Biol2005https://conductscience.org/library/papers/16243526PubMed
716,327,811Conservation of gene expression signatures between zebrafish and human liver tumors and tumor progression.Nat Biotechnol2006https://conductscience.org/library/papers/16327811PubMed
815,908,567Survivin-directed RNA interference cocktail is a potent suppressor of tumour growth in vivo.J Med Genet2006https://conductscience.org/library/papers/15908567PubMed
916,518,851Mutations of the PTPN11 and RAS genes in rhabdomyosarcoma and pediatric hematological malignancies.Genes Chromosomes Cancer2006https://conductscience.org/library/papers/16518851PubMed
1016,862,118Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9.Nature2006https://conductscience.org/library/papers/16862118PubMed

1 to 10 of 53

See all 53 references

Cited by197

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 272 citations.

PMIDTitleJournalYearIn PapersSource
42,802,717Zebrafish against cancer: towards clinical relevance.Dis Model Mech2026https://conductscience.org/library/papers/42802717PubMed
42,699,321The CNNM-binding interface drives PRL-3-dependent tumor progression in de novo cancer models.iScience2026https://conductscience.org/library/papers/42699321PubMed
42,236,477MYOD1 mutation drives cancer stem cell pathways and therapy-resistance in spindle cell/sclerosing rhabdomyosarcoma.Nat Commun2026https://conductscience.org/library/papers/42236477PubMed
41,899,494Biological Advances and Current Challenges for Pediatric Rhabdomyosarcoma.Cancers (Basel)2026https://conductscience.org/library/papers/41899494PubMed
41,888,798Beyond the mouse: 3R-guided alternative animal models transforming cancer research.Mol Cancer2026https://conductscience.org/library/papers/41888798PubMed
41,513,885Choosing the right animal model for sarcoma research.Cell Mol Life Sci2026https://conductscience.org/library/papers/41513885PubMed
41,372,143The PIK3CA/AKT pathway drives therapy resistance in rhabdomyosarcoma.Nat Commun2025https://conductscience.org/library/papers/41372143PubMed
41,248,180The impact of RAS on cell differentiation in health and disease.Biochem J2025https://conductscience.org/library/papers/41248180PubMed
40,810,172Photodynamic Therapy Using a Heavy-Atom-Free G‑Quadruplex-Targeted Photosensitizer to Efficiently Regress Rhabdomyosarcoma Tumors In Vivo.ACS Pharmacol Transl Sci2025https://conductscience.org/library/papers/40810172PubMed
40,469,193A dual readout embryonic zebrafish xenograft model of rhabdomyosarcoma to assess clinically relevant multi-receptor tyrosine kinase inhibitors.Front Oncol2025https://conductscience.org/library/papers/40469193PubMed

1 to 10 of 197

See all 197 cited by

Genes2

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
ADA100PubTator's text mininghttps://conductscience.org/library/genes/100NCBI Gene
ADARB1104PubTator's text mininghttps://conductscience.org/library/genes/104NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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