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Paper · 17529973

A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer.

Hunter DJ and 29 others. Nat Genet, 2007. Cited by 1,173 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer. Papers, record 17529973. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/17529973

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer.
PubMed
Journal
Nat Genet
PubMed
Year
2007
PubMed
Publication types
Journal Article, Research Support, N.I.H., Extramural, Research Support, N.I.H., Intramural
PubMed
Citations, by iCite
1,173
iCite
Relative citation ratio, by iCite
24.5
iCite
Revised in PubMed
2024-04-18
PubMed

Authors30

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Hunter DJDavid J
2Kraft PPeter
3Jacobs KBKevin B
4Cox DGDavid G
5Yeager MMeredith
6Hankinson SESusan E
7Wacholder SSholom
8Wang ZZhaoming
9Welch RRobert
10Hutchinson AAmy

1 to 10 of 30Source PubMed

See all 30 authors

Topics12

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
AllelesMajor topic
Breast NeoplasmsMajor topic
Genetic Predisposition to DiseaseMajor topic
Genome, HumanMajor topic
PostmenopauseMajor topic
Receptor, Fibroblast Growth Factor, Type 2Major topic
Aged
Female
Humans
Middle Aged
Polymorphism, Single Nucleotide
Risk Factors

Source PubMed

Grants19

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated bySource
R01 CA050385NCI NIH HHSUnited StatesR01CA050385PubMed and NIHNIH RePORTER
P01 CA087969NCI NIH HHSUnited StatesP01CA087969PubMed and NIHNIH RePORTER
R01 CA067262NCI NIH HHSUnited StatesR01CA067262PubMed and NIHNIH RePORTER
5U01CA098233NCI NIH HHSUnited StatesU01CA098233PubMed and NIHNIH RePORTER
CA87969NCI NIH HHSUnited StatesP01CA087969PubMed and NIHNIH RePORTER
CA49449NCI NIH HHSUnited StatesR01CA049449PubMed and NIHNIH RePORTER
U01 CA067262NCI NIH HHSUnited StatesR01CA067262PubMed and NIHNIH RePORTER
R01 CA065725NCI NIH HHSUnited StatesR01CA065725PubMed and NIHNIH RePORTER
CA67262NCI NIH HHSUnited StatesR01CA067262PubMed and NIHNIH RePORTER
Intramural NIH HHSUnited StatesPubMedPubMed

1 to 10 of 19

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Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References22

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
14,050,778Estimating the population attributable risk for multiple risk factors using case-control data.Am J Epidemiol1985https://conductscience.org/library/papers/4050778PubMed
211,189,687Etiologic and early marker studies in the prostate, lung, colorectal and ovarian (PLCO) cancer screening trial.Control Clin Trials2000https://conductscience.org/library/papers/11189687PubMed
316,775,186Association of polymorphisms in the paraoxonase 1 gene with breast cancer incidence in the CPS-II Nutrition Cohort.Cancer Epidemiol Biomarkers Prev2006https://conductscience.org/library/papers/16775186PubMed
417,372,279A prospective study of plasma prolactin concentrations and risk of premenopausal and postmenopausal breast cancer.J Clin Oncol2007https://conductscience.org/library/papers/17372279PubMed
517,407,163RNASEL Arg462Gln polymorphism and prostate cancer in PLCO.Prostate2007https://conductscience.org/library/papers/17407163PubMed
617,194,218Population structure and eigenanalysis.PLoS Genet2006https://conductscience.org/library/papers/17194218PubMed
715,863,033Fibroblast growth factor signaling in tumorigenesis.Cytokine Growth Factor Rev2005https://conductscience.org/library/papers/15863033PubMed
817,033,967Mapping trait loci by use of inferred ancestral recombination graphs.Am J Hum Genet2006https://conductscience.org/library/papers/17033967PubMed
911,984,562Polygenic susceptibility to breast cancer and implications for prevention.Nat Genet2002https://conductscience.org/library/papers/11984562PubMed
1017,401,366Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24.Nat Genet2007https://conductscience.org/library/papers/17401366PubMed

1 to 10 of 22

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Cited by843

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 1,173 citations.

PMIDTitleJournalYearIn PapersSource
41,607,670Shared and Sex-Specific Genetic Risk for Parkinson's Disease Risk Across European Populations.medRxiv2026https://conductscience.org/library/papers/41607670PubMed
41,369,841Breast Cancer Progression by the FGF/FGFR Axis: A Metabolic Perspective.J Mammary Gland Biol Neoplasia2025https://conductscience.org/library/papers/41369841PubMed
41,318,657RAD51B-EZH2 axis as a potential therapeutic target for TNBC through cell fate conversion.Cell Death Dis2025https://conductscience.org/library/papers/41318657PubMed
40,748,883Association of FGF Receptor-2rs2981578 SNP with breast cancer in women at the University of Gondar Comprehensive Specialized Hospital, Ethiopia.PLoS One2025https://conductscience.org/library/papers/40748883PubMed
40,722,182Missense variants in PRKCD: elucidating their potential association with breast cancer.Breast Cancer Res2025https://conductscience.org/library/papers/40722182PubMed
40,621,597FGFR2-Rearrangement in Intrahepatic and Extrahepatic Cholangiocarcinoma and Prognostic Analysis.Int J Gen Med2025https://conductscience.org/library/papers/40621597PubMed
40,574,466The sequence kernel association test for the proportional odds model.Bioinformatics2025https://conductscience.org/library/papers/40574466PubMed
40,388,204Beacon Reconstruction Attack: Reconstruction of genomes in genomic data-sharing beacons using summary statistics.Bioinformatics2025https://conductscience.org/library/papers/40388204PubMed
40,233,739Precision proteogenomics reveals pan-cancer impact of germline variants.Cell2025https://conductscience.org/library/papers/40233739PubMed
39,596,875Lower FGFR2 mRNA Expression and Higher Levels of FGFR2 IIIc in HER2-Positive Breast Cancer.Biology (Basel)2024https://conductscience.org/library/papers/39596875PubMed

1 to 10 of 843

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Genes1

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn Genes
FGFR22,263PubTator's text mininghttps://conductscience.org/library/genes/2263

Source NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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