Paper · 19190071

Leptin at 14 y of age: an ongoing story.

Friedman JM. Am J Clin Nutr, 2009. Cited by 194 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Leptin at 14 y of age: an ongoing story. Papers, record 19190071. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/19190071

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Leptin at 14 y of age: an ongoing story.; PubMed
Journal: Am J Clin Nutr; PubMed
Year: 2009; PubMed
Publication types: Journal Article, Research Support, Non-U.S. Gov't, Review; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/19190071/; PubMed
DOI: https://doi.org/10.3945/ajcn.2008.26788b; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC2667654/; PubMed
The journal: https://conductscience.org/library/journal-index/0376027; PubMed
Citations, by iCite: 194; iCite
Relative citation ratio, by iCite: 4.86; iCite
Revised in PubMed: 2025-01-06; PubMed

Authors1

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	Kind	ORCID iD
1	Friedman JM	Jeffrey M

Source PubMed

Topics6

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Leptin	Major topic
Adipose Tissue
Animals
Body Weight
Cloning, Molecular
Humans

Source PubMed

Grants1

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes it	Agency	Country	NIH project	Stated by
	Howard Hughes Medical Institute	United States		PubMed

Source PubMed

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References64

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	2,336,075	The body-mass index of twins who have been reared apart.	N Engl J Med	1990	https://conductscience.org/library/papers/2336075	PubMed
2	2,276,853	Obesity: historical development of scientific and cultural ideas.	Int J Obes	1990	https://conductscience.org/library/papers/2276853	PubMed
3	2,260,725	Identification of candidate genes for a factor regulating body weight in primates.	Am J Physiol	1990	https://conductscience.org/library/papers/2260725	PubMed
4	3,235,273	Contribution of decreased body mass to diminished thermic effect of exercise in reduced-obese men.	Int J Obes	1988	https://conductscience.org/library/papers/3235273	PubMed
5	9,751,754	Abnormal regulation of the leptin gene in the pathogenesis of obesity.	Proc Natl Acad Sci U S A	1998	https://conductscience.org/library/papers/9751754	PubMed
6	19,176,738	Leptin: weight management and beyond. Introduction to the symposium.	Am J Clin Nutr	2009	https://conductscience.org/library/papers/19176738	PubMed
7	16,186,728	Fat distribution in men with HIV infection.	J Acquir Immune Defic Syndr	2005	https://conductscience.org/library/papers/16186728	PubMed
8	11,856,796	Leptin-replacement therapy for lipodystrophy.	N Engl J Med	2002	https://conductscience.org/library/papers/11856796	PubMed
9	12,574,619	A war on obesity, not the obese.	Science	2003	https://conductscience.org/library/papers/12574619	PubMed
10	9,192,681	Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues.	Proc Natl Acad Sci U S A	1997	https://conductscience.org/library/papers/9192681	PubMed

1 to 10 of 64

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Cited by126

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 194 citations.

PMID	Title	Journal	Year	In Papers	Source
42,427,597	Leptin alleviates obesity hypoventilation via serotonergic pathways.	bioRxiv	2026	https://conductscience.org/library/papers/42427597	PubMed
41,476,920	Adipose-androgen crosstalk in polycystic ovary syndrome: mechanisms and therapeutic implications.	Front Endocrinol (Lausanne)	2025	https://conductscience.org/library/papers/41476920	PubMed
38,707,092	Correlation of Leptin in Patients With Type 2 Diabetes Mellitus.	Cureus	2024	https://conductscience.org/library/papers/38707092	PubMed
38,039,129	Leptin signaling in the dorsomedial hypothalamus couples breathing and metabolism in obesity.	Cell Rep	2023	https://conductscience.org/library/papers/38039129	PubMed
37,581,939	Suppression of food intake by Glp1r/Lepr-coexpressing neurons prevents obesity in mouse models.	J Clin Invest	2023	https://conductscience.org/library/papers/37581939	PubMed
37,155,466	Effects of leptin on the viability of human ovarian cancer cells and changes in cytokine expression levels.	PeerJ	2023	https://conductscience.org/library/papers/37155466	PubMed
37,043,384	Identification of a GABAergic neural circuit governing leptin signaling deficiency-induced obesity.	Elife	2023	https://conductscience.org/library/papers/37043384	PubMed
36,479,639	Metabolic effects of lipectomy and of adipose tissue transplantation.	Obesity (Silver Spring)	2023	https://conductscience.org/library/papers/36479639	PubMed
36,246,998	Egr1 plays a major role in the transcriptional response of white adipocytes to insulin and environmental cues.	Front Cell Dev Biol	2022	https://conductscience.org/library/papers/36246998	PubMed
36,214,387	TRPM7 channels regulate breathing during sleep in obesity by acting peripherally in the carotid bodies.	J Physiol	2022	https://conductscience.org/library/papers/36214387	PubMed

1 to 10 of 126

See all 126 cited by

Genes1

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes
LEP	3,952	PubTator's text mining	https://conductscience.org/library/genes/3952

Source NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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