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Paper196100

Regulation of early and late simian virus 40 transcription: overproduction of early viral RNA in the absence of a functional T-antigen.

Khoury G and 1 other. J Virol, 1977. Cited by 161 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Regulation of early and late simian virus 40 transcription: overproduction of early viral RNA in the absence of a functional T-antigen. Papers, record 196100. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/196100

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Regulation of early and late simian virus 40 transcription: overproduction of early viral RNA in the absence of a functional T-antigen.
PubMed
Journal
J Virol
PubMed
Year
1977
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
161
iCite
Relative citation ratio, by iCite
3.24
iCite
Revised in PubMed
2020-07-24
PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Khoury GG
2May EE

Source PubMed

Topics14

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Antigens, ViralMajor topic
Histocompatibility AntigensMajor topic
RNA, MessengerMajor topic
RNA, ViralMajor topic
Simian virus 40Major topic
Transcription, GeneticMajor topic
Cell Line
Cytarabine
Cytoplasm
DNA Replication
DNA, Viral
Mutation
RNA
Temperature

Source PubMed

References24

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
11,061,069Lambda repressor turns off transcription of its own gene.Proc Natl Acad Sci U S A1975https://conductscience.org/library/papers/1061069PubMed
2959,843Autoregulation and function of a repressor in bacteriophage lambda.Science1976https://conductscience.org/library/papers/959843PubMed
31,255,869Viral transcription in KB cells infected by temperature-sensitive "early" mutants of adenovirus type 5.J Virol1976https://conductscience.org/library/papers/1255869PubMed
4163,366Posttranscriptional selection of simian virus 40-specific RNA.J Virol1975https://conductscience.org/library/papers/163366PubMed
5165,517T antigen binds to simian virus 40 DNA at the origin of replication.Proc Natl Acad Sci U S A1975https://conductscience.org/library/papers/165517PubMed
6166,203Regulation of tumor antigen synthesis by simain virus 40 gene A.J Virol1975https://conductscience.org/library/papers/166203PubMed
7169,150Isolation and partial characterization of a nuclear RNA polymerase - SV40 DNA complex.FEBS Lett1975https://conductscience.org/library/papers/169150PubMed
8171,448Transcription of simian virus 40. V. Regulattion of simian virus 40 gene expression.J Virol1975https://conductscience.org/library/papers/171448PubMed
9171,628Mapping the transcription site of the SV40-specific late 16 S mRNA.Nucleic Acids Res1975https://conductscience.org/library/papers/171628PubMed
10179,059Isolation and characterization of poly(A)-containing polyoma "early" and "late" messenger RNAs.Nucleic Acids Res1976https://conductscience.org/library/papers/179059PubMed
11182,375Preferential synthesis of viral late RNA by nuclei isolated from SV40 lytically infected cells.Cell1976https://conductscience.org/library/papers/182375PubMed
12184,459Autoregulation of simian virus 40 gene A by T antigen.Proc Natl Acad Sci U S A1976https://conductscience.org/library/papers/184459PubMed
134,291,934Selective extraction of polyoma DNA from infected mouse cell cultures.J Mol Biol1967https://conductscience.org/library/papers/4291934PubMed
144,342,195Transcription of Simian virus 40. I. Separation of the strands of SV40 DNA and hybridization of the separated strands to RNA extracted from lytically infected and transformed cells.J Mol Biol1972https://conductscience.org/library/papers/4342195PubMed
154,342,237Isolation and characterization of simian virus 40 ribonucleic acid.J Virol1972https://conductscience.org/library/papers/4342237PubMed
164,352,963Relationship of replication and transcription of Simian Virus 40 DNA.Proc Natl Acad Sci U S A1973https://conductscience.org/library/papers/4352963PubMed
174,354,250Detection of two restriction endonuclease activities in Haemophilus parainfluenzae using analytical agarose--ethidium bromide electrophoresis.Biochemistry1973https://conductscience.org/library/papers/4354250PubMed
184,355,834A map of simian virus 40 transcription sites expressed in productively infected cells.J Mol Biol1973https://conductscience.org/library/papers/4355834PubMed
194,366,021Viral DNA synthesis in cells infected by temperature-sensitive mutants of simian virus 40.J Virol1974https://conductscience.org/library/papers/4366021PubMed
204,367,488Inhibitors of DNA synthesis: their influence on replication and transcription of simian virus 40 DNA.Virology1974https://conductscience.org/library/papers/4367488PubMed

See all 24 references

Cited by85

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 161 citations.

PMIDTitleJournalYearIn PapersSource
42,845,301SV40 Large T antigen inhibits the host serine protease FAM111A through a zinc-dependent, cleavage-avoiding mechanism.bioRxiv2026https://conductscience.org/library/papers/42845301PubMed
24,586,168Insights into the initiation of JC virus DNA replication derived from the crystal structure of the T-antigen origin binding domain.PLoS Pathog2014https://conductscience.org/library/papers/24586168PubMed
23,269,808Analysis of the costructure of the simian virus 40 T-antigen origin binding domain with site I reveals a correlation between GAGGC spacing and spiral assembly.J Virol2013https://conductscience.org/library/papers/23269808PubMed
17,109,635Protein encoded by HSV-1 stimulation-related gene 1 (HSRG1) interacts with and inhibits SV40 large T antigen.Cell Prolif2006https://conductscience.org/library/papers/17109635PubMed
12,692,206Simian virus 40 infection of humans.J Virol2003https://conductscience.org/library/papers/12692206PubMed
8,627,669Functional comparison of PML-type and archetype strains of JC virus.J Virol1996https://conductscience.org/library/papers/8627669PubMed
8,383,222Simian virus 40 (SV40) T-antigen mutations in tumorigenic transformation of SV40-immortalized human uroepithelial cells.J Virol1993https://conductscience.org/library/papers/8383222PubMed
6,542,172Introduction, stable integration, and controlled expression of a chimeric adenovirus gene whose product is toxic to the recipient human cell.Mol Cell Biol1984https://conductscience.org/library/papers/6542172PubMed
6,325,152Transcription of Simian Virus 40 chromosomes in an extract of HeLa cells.EMBO J1982https://conductscience.org/library/papers/6325152PubMed
6,321,788Simian virus 40 late promoter region able to initiate simian virus 40 early gene transcription in the absence of the simian virus 40 origin sequence.J Virol1984https://conductscience.org/library/papers/6321788PubMed
6,317,896Expression of viral early functions in rat 3Y1 cells infected with human papovavirus BK.J Virol1984https://conductscience.org/library/papers/6317896PubMed
6,312,077Stabilization of the large T protein in temperature-independent (type A) FR 3T3 rat cells transformed with the simian virus 40 tsA30 mutant.J Virol1983https://conductscience.org/library/papers/6312077PubMed
6,310,149Microinjected simian virus 40 cRNA is spliced, as evidenced by electron microscopy.J Virol1983https://conductscience.org/library/papers/6310149PubMed
6,300,658Biochemical activities of T-antigen proteins encoded by simian virus 40 A gene deletion mutants.Mol Cell Biol1983https://conductscience.org/library/papers/6300658PubMed
6,300,657Mutational analysis of simian virus 40 T antigen: stimulation of cellular DNA synthesis and activation of rRNA genes by mutants with deletions in the T-antigen gene.Mol Cell Biol1983https://conductscience.org/library/papers/6300657PubMed
6,300,656Mutational analysis of simian virus 40 T antigen: isolation and characterization of mutants with deletions in the T-antigen gene.Mol Cell Biol1983https://conductscience.org/library/papers/6300656PubMed
6,298,607Plasmid-directed synthesis of hepatitis B surface antigen in monkey cells.Mol Cell Biol1983https://conductscience.org/library/papers/6298607PubMed
6,292,510DNA binding properties of simian virus 40 temperature-sensitive A proteins.J Virol1982https://conductscience.org/library/papers/6292510PubMed
6,284,959Simian virus 40 mutant with transposed T-antigen and VP1 genes.J Virol1982https://conductscience.org/library/papers/6284959PubMed
6,281,460Initiation and regulation of simian virus 40 early transcription in vitro.J Virol1982https://conductscience.org/library/papers/6281460PubMed

See all 85 cited by

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

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Sources 11

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  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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