Paper · 200739

Synaptic excitation and inhibition resulting from direct action of acetylcholine on two types of chemoreceptors on individual amphibian parasympathetic neurones.

Hartzell HC and 3 others. J Physiol, 1977. Cited by 212 papers, by iCite.

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ConductScience Library. Synaptic excitation and inhibition resulting from direct action of acetylcholine on two types of chemoreceptors on individual amphibian parasympathetic neurones. Papers, record 200739. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/200739

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Synaptic excitation and inhibition resulting from direct action of acetylcholine on two types of chemoreceptors on individual amphibian parasympathetic neurones.; PubMed
Journal: J Physiol; PubMed
Year: 1977; PubMed
Publication types: Journal Article, Research Support, U.S. Gov't, P.H.S.; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/200739/; PubMed
DOI: https://doi.org/10.1113/jphysiol.1977.sp012027; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC1353634/; PubMed
The journal: https://conductscience.org/library/journal-index/0266262; PubMed
Citations, by iCite: 212; iCite
Relative citation ratio, by iCite: 6.79; iCite
Revised in PubMed: 2025-01-03; PubMed

Authors4

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Hartzell HC	H C
2	Kuffler SW	S W
3	Stickgold R	R
4	Yoshikami D	D

Source PubMed

Topics13

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Acetylcholine	Major topic
Parasympathetic Nervous System	Major topic
Receptors, Cholinergic	Major topic
Synaptic Transmission	Major topic
Action Potentials
Animals
Bethanechol Compounds
In Vitro Techniques
Membrane Potentials
Neural Inhibition
Synapses
Time Factors
Caudata

Source PubMed

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Trials0

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Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References25

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	14,278,409	THE MEASUREMENT OF SYNAPTIC DELAY, AND THE TIME COURSE OF ACETYLCHOLINE RELEASE AT THE NEUROMUSCULAR JUNCTION.	Proc R Soc Lond B Biol Sci	1965	https://conductscience.org/library/papers/14278409	PubMed
2	13,725,578	Origin and blockade of the synaptic responses of curarized sympathetic ganglia.	J Physiol	1961	https://conductscience.org/library/papers/13725578	PubMed
7	1,086,900	Changes in membrane currents in bullfrog atrium produced by acetylcholine.	J Physiol	1976	https://conductscience.org/library/papers/1086900	PubMed
8	11,484	On the latency and form of the membrane responses of smooth muscle to the iontophoretic application of acetylcholine or carbachol.	Proc R Soc Lond B Biol Sci	1976	https://conductscience.org/library/papers/11484	PubMed
9	4,475,409	Nonlinear voltage dependence of excitatory synaptic current in crayfish muscle.	Pflugers Arch	1974	https://conductscience.org/library/papers/4475409	PubMed
10	4,543,940	Voltage clamp analysis of acetylcholine produced end-plate current fluctuations at frog neuromuscular junction.	J Physiol	1973	https://conductscience.org/library/papers/4543940	PubMed
11	4,399,739	Dopamine as a synaptic transmitter and modulator in sympathetic ganglia: a different mode of synaptic action.	Proc Natl Acad Sci U S A	1970	https://conductscience.org/library/papers/4399739	PubMed
12	4,396,518	Synaptic transmission and its duplication by focally applied acetylcholine in parasympathetic neurons in the heart of the frog.	Proc R Soc Lond B Biol Sci	1971	https://conductscience.org/library/papers/4396518	PubMed
13	166,160	The distribution of acetylcholine sensitivity at the post-synaptic membrane of vertebrate skeletal twitch muscles: iontophoretic mapping in the micron range.	J Physiol	1975	https://conductscience.org/library/papers/166160	PubMed
14	175,155	The acetylcholine sensitivity of the surface membrane of multiply-innervated parasympathetic ganglion cells in the mudpuppy before and after partial denervation.	J Physiol	1976	https://conductscience.org/library/papers/175155	PubMed

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Cited by75

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 212 citations.

PMID	Title	Journal	Year	In Papers	Source
42,148,257	Festschrift in honor of Dr. Robert Stickgold, pioneer in sleep, memory, and dream research.	Sleep Adv	2026	https://conductscience.org/library/papers/42148257	PubMed
29,351,282	A four-component model of the action potential in mouse detrusor smooth muscle cell.	PLoS One	2018	https://conductscience.org/library/papers/29351282	PubMed
26,203,111	Functional connectivity in raphé-pontomedullary circuits supports active suppression of breathing during hypocapnic apnea.	J Neurophysiol	2015	https://conductscience.org/library/papers/26203111	PubMed
23,357,106	Abundance, distribution, mobility and oligomeric state of M₂ muscarinic acetylcholine receptors in live cardiac muscle.	J Mol Cell Cardiol	2013	https://conductscience.org/library/papers/23357106	PubMed
22,969,726	Extrasynaptic exocytosis and its mechanisms: a source of molecules mediating volume transmission in the nervous system.	Front Physiol	2012	https://conductscience.org/library/papers/22969726	PubMed
19,756,262	Dynamic Clamp Analysis of Synaptic Integration in Sympathetic Ganglia.	Neirofiziologiia	2007	https://conductscience.org/library/papers/19756262	PubMed
17,495,034	Neurally released pituitary adenylate cyclase-activating polypeptide enhances guinea pig intrinsic cardiac neurone excitability.	J Physiol	2007	https://conductscience.org/library/papers/17495034	PubMed
11,929,887	Calcium-induced transitions between the spontaneous miniature outward and the transient outward currents in retinal amacrine cells.	J Gen Physiol	2002	https://conductscience.org/library/papers/11929887	PubMed
11,929,886	Mechanism of generation of spontaneous miniature outward currents (SMOCs) in retinal amacrine cells.	J Gen Physiol	2002	https://conductscience.org/library/papers/11929886	PubMed
11,699,940	Temperature effect on carbachol-induced depression of spontaneous quantal transmitter release in frog neuromuscular junction.	Neurochem Res	2001	https://conductscience.org/library/papers/11699940	PubMed

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Data0

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Data dates

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PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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ClinicalTrials.govNo license stated
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iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

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ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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