Paper · 20121268

An integrated system for DNA sequencing by synthesis using novel nucleotide analogues.

Guo J and 3 others. Acc Chem Res, 2010. Cited by 44 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. An integrated system for DNA sequencing by synthesis using novel nucleotide analogues. Papers, record 20121268. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/20121268

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: An integrated system for DNA sequencing by synthesis using novel nucleotide analogues.; PubMed
Journal: Acc Chem Res; PubMed
Year: 2010; PubMed
Publication types: Journal Article, Research Support, N.I.H., Extramural, Research Support, U.S. Gov't, Non-P.H.S.; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/20121268/; PubMed
DOI: https://doi.org/10.1021/ar900255c; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC2857541/; PubMed
The journal: https://conductscience.org/library/journal-index/0157313; PubMed
Citations, by iCite: 44; iCite
Relative citation ratio, by iCite: 1.03; iCite
Revised in PubMed: 2025-05-29; PubMed

Authors4

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Guo J	Jia
2	Yu L	Lin
3	Turro NJ	Nicholas J
4	Ju J	Jingyue

Source PubMed

Topics6

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
DNA	Major topic
Nucleotides	Major topic
Sequence Analysis, DNA	Major topic
DNA Primers
DNA-Directed DNA Polymerase
Fluorescent Dyes

Source PubMed

Grants8

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes it	Agency	Country	NIH project	Stated by	Source
R01 HG003582	NHGRI NIH HHS	United States	R01HG003582	PubMed and NIH	NIH RePORTER
R21 HG004404	NHGRI NIH HHS	United States	R21HG004404	PubMed and NIH	NIH RePORTER
R01 NS060762	NINDS NIH HHS	United States	R01NS060762	PubMed and NIH	NIH RePORTER
R01HG003582	NHGRI NIH HHS	United States	R01HG003582	PubMed and NIH	NIH RePORTER
R21HG004404	NHGRI NIH HHS	United States	R21HG004404	PubMed and NIH	NIH RePORTER
R01 HG005109	NHGRI NIH HHS	United States	R01HG005109	PubMed and NIH	NIH RePORTER
R01NS060762	NINDS NIH HHS	United States	R01NS060762	PubMed and NIH	NIH RePORTER
R01HG005109	NHGRI NIH HHS	United States	R01HG005109	PubMed and NIH	NIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References38

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	19,620,973	Virtual terminator nucleotides for next-generation DNA sequencing.	Nat Methods	2009	https://conductscience.org/library/papers/19620973	PubMed
2	12,651,960	Sequence information can be obtained from single DNA molecules.	Proc Natl Acad Sci U S A	2003	https://conductscience.org/library/papers/12651960	PubMed
3	18,421,352	The complete genome of an individual by massively parallel DNA sequencing.	Nature	2008	https://conductscience.org/library/papers/18421352	PubMed
4	12,895,469	Fluorescent in situ sequencing on polymerase colonies.	Anal Biochem	2003	https://conductscience.org/library/papers/12895469	PubMed
5	8,643,470	DNA sequencing by delayed extraction-matrix-assisted laser desorption/ionization time of flight mass spectrometry.	Proc Natl Acad Sci U S A	1996	https://conductscience.org/library/papers/8643470	PubMed
6	17,170,132	Four-color DNA sequencing by synthesis using cleavable fluorescent nucleotide reversible terminators.	Proc Natl Acad Sci U S A	2006	https://conductscience.org/library/papers/17170132	PubMed
7	17,512,414	High-resolution profiling of histone methylations in the human genome.	Cell	2007	https://conductscience.org/library/papers/17512414	PubMed
8	271,968	DNA sequencing with chain-terminating inhibitors.	Proc Natl Acad Sci U S A	1977	https://conductscience.org/library/papers/271968	PubMed
9	18,463,631	An endogenous small interfering RNA pathway in Drosophila.	Nature	2008	https://conductscience.org/library/papers/18463631	PubMed
10	9,358,158	New dye-labeled terminators for improved DNA sequencing patterns.	Nucleic Acids Res	1997	https://conductscience.org/library/papers/9358158	PubMed

1 to 10 of 38

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Cited by23

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 44 citations.

PMID	Title	Journal	Year	In Papers	Source
42,206,681	Host-Pathogen Dual Targeting With Repurposed Drugs Identifies a Synergistic Therapy for Intracellular Staphylococcus aureus.	Microbiologyopen	2026	https://conductscience.org/library/papers/42206681	PubMed
40,071,471	Genomic and transcriptomic sequencing in prostate cancer.	Curr Opin Oncol	2025	https://conductscience.org/library/papers/40071471	PubMed
38,890,393	Controlled enzymatic synthesis of oligonucleotides.	Commun Chem	2024	https://conductscience.org/library/papers/38890393	PubMed
38,818,014	Can long-read sequencing tackle the barriers, which the next-generation could not? A review.	Pathol Oncol Res	2024	https://conductscience.org/library/papers/38818014	PubMed
37,197,021	Decoding the microbial universe with metagenomics: a brief insight.	Front Genet	2023	https://conductscience.org/library/papers/37197021	PubMed
35,996,537	Multiplexed Single-Cell in Situ Protein Profiling.	ACS Meas Sci Au	2022	https://conductscience.org/library/papers/35996537	PubMed
34,063,986	Highly Sensitive and Multiplexed In Situ RNA Profiling with Cleavable Fluorescent Tyramide.	Cells	2021	https://conductscience.org/library/papers/34063986	PubMed
33,113,917	Highly Multiplexed Single-Cell In Situ RNA and DNA Analysis by Consecutive Hybridization.	Molecules	2020	https://conductscience.org/library/papers/33113917	PubMed
32,748,522	Single-cell proteomic analysis.	WIREs Mech Dis	2021	https://conductscience.org/library/papers/32748522	PubMed
32,372,056	Enzymatic Cleavage of 3'-Esterified Nucleotides Enables a Long, Continuous DNA Synthesis.	Sci Rep	2020	https://conductscience.org/library/papers/32372056	PubMed

1 to 10 of 23

See all 23 cited by

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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