Paper · 20175978

In early OA, thinning of the subchondral plate is directly related to cartilage damage: results from a canine ACLT-meniscectomy model.

Intema F and 6 others. Osteoarthritis Cartilage, 2010. Cited by 138 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. In early OA, thinning of the subchondral plate is directly related to cartilage damage: results from a canine ACLT-meniscectomy model. Papers, record 20175978. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/20175978

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: In early OA, thinning of the subchondral plate is directly related to cartilage damage: results from a canine ACLT-meniscectomy model.; PubMed
Journal: Osteoarthritis Cartilage; PubMed
Year: 2010; PubMed
Publication types: Journal Article, Research Support, Non-U.S. Gov't; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/20175978/; PubMed
DOI: https://doi.org/10.1016/j.joca.2010.01.004; PubMed
The journal: https://conductscience.org/library/journal-index/9305697; PubMed
Citations, by iCite: 138; iCite
Relative citation ratio, by iCite: 4.94; iCite
Revised in PubMed: 2016-10-18; PubMed

Authors7

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Intema F	F
2	Hazewinkel HA	H A W
3	Gouwens D	D
4	Bijlsma JW	J W J
5	Weinans H	H
6	Lafeber FP	F P J G
7	Mastbergen SC	S C

Source PubMed

Topics10

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Cartilage, Articular	Major topic
Knee Joint	Major topic
Osteoarthritis, Knee	Major topic
Animals
Anterior Cruciate Ligament
Disease Models, Animal
Dogs
Glycosaminoglycans
Menisci, Tibial
Tomography, X-Ray Computed

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

None in this release.

Cited by68

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 138 citations.

PMID	Title	Journal	Year	In Papers	Source
42,260,301	Relative HU profiling on clinical CT estimates the subchondral bone plate boundary: an ex vivo cadaveric mechanical validation study.	Sci Rep	2026	https://conductscience.org/library/papers/42260301	PubMed
41,751,182	A Novel Concept of Tissue Micro-Instability as the Underlying Mechanism of Osteophytosis in Human Knee Osteoarthritis.	Biomedicines	2026	https://conductscience.org/library/papers/41751182	PubMed
41,398,702	The Notch signaling pathway in regulating bone and cartilage homeostasis: novel insights into the pathogenesis and therapeutics of osteoarthritis.	Cell Commun Signal	2025	https://conductscience.org/library/papers/41398702	PubMed
41,344,441	Human Knee as an Organ: Joint Tissue Collection, Processing, and Scoring for Multimodal Analyses.	Lab Invest	2026	https://conductscience.org/library/papers/41344441	PubMed
41,112,124	Effect of Antiresorptive Therapy on Development of Posttraumatic Osteoarthritis after Intra-articular Distal Radius Fracture in Female Patients.	Clin Orthop Surg	2025	https://conductscience.org/library/papers/41112124	PubMed
40,543,563	Concurrent joint contact in anterior cruciate ligament injury induces cartilage micro-injury and subchondral bone sclerosis, resulting in knee osteoarthritis.	Osteoarthritis Cartilage	2026	https://conductscience.org/library/papers/40543563	PubMed
40,384,664	Exploring the asynchronous changes of articular cartilage and osteochondral junction in knee osteoarthritis based on T2 mapping and ultrashort echo time imaging: a pilot study.	Quant Imaging Med Surg	2025	https://conductscience.org/library/papers/40384664	PubMed
40,384,207	Hip osteoarthritis - histopathological aspects.	Rom J Morphol Embryol	2025	https://conductscience.org/library/papers/40384207	PubMed
40,143,645	Liposome-Based Interventions in Knee Osteoarthritis.	Small	2025	https://conductscience.org/library/papers/40143645	PubMed
39,298,537	The oral intake of specific Bioactive Collagen Peptides (BCP) improves gait and quality of life in canine osteoarthritis patients-A translational large animal model for a nutritional therapy option.	PLoS One	2024	https://conductscience.org/library/papers/39298537	PubMed

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Genes0

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None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

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PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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