Paper20501

Continuous direct measurement of intracellular chloride and pH in frog skeletal muscle.

Bolton TB and 1 other. J Physiol, 1977. Cited by 104 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

Cite this record

ConductScience Library. Continuous direct measurement of intracellular chloride and pH in frog skeletal muscle. Papers, record 20501. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/20501

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Continuous direct measurement of intracellular chloride and pH in frog skeletal muscle.; PubMed
Journal: J Physiol; PubMed
Year: 1977; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/20501/; PubMed
DOI: https://doi.org/10.1113/jphysiol.1977.sp011983; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC1353546/; PubMed
The journal: https://conductscience.org/library/journal-index/0266262; PubMed
Citations, by iCite: 104; iCite
Relative citation ratio, by iCite: 3.76; iCite
Revised in PubMed: 2019-05-09; PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	Kind	ORCID iD
1	Bolton TB	T B
2	Vaughan-Jones RD	R D

Source PubMed

Topics13

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Chlorides	Major topic
Muscles	Major topic
Animals
Anura
Bicarbonates
Biological Transport, Active
Hydrogen-Ion Concentration
In Vitro Techniques
Intracellular Fluid
Membrane Potentials
Microelectrodes
Potassium
Rana temporaria

Source PubMed

Show 7 more topicsShow fewer topics

References31

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
2	4,838,803	Intracellular pH of snail neurones measured with a new pH-sensitive glass mirco-electrode.	J Physiol	1974	https://conductscience.org/library/papers/4838803	PubMed
3	13,203	Intracellular pH of single crustacean muscle fibres by the DMO and electrode methods during acid and alkaline conditions.	J Physiol	1976	https://conductscience.org/library/papers/13203	PubMed
4	10,431	Intracellular pH of mouse soleus muscle [proceedings].	J Physiol	1976	https://conductscience.org/library/papers/10431	PubMed
5	16,992,510	Chloride distribution in Aplysia neurones.	J Physiol	1976	https://conductscience.org/library/papers/16992510	PubMed
6	13,952,913	Distribution and movement of muscle chloride.	J Physiol	1963	https://conductscience.org/library/papers/13952913	PubMed
7	13,205	Direct measurement of the intracellular pH of mammalian cardiac muscle.	J Physiol	1976	https://conductscience.org/library/papers/13205	PubMed
8	5,579,636	The distribution of chloride ions in the smooth muscle cells of the guinea-pig's taenia coli.	J Physiol	1971	https://conductscience.org/library/papers/5579636	PubMed
9	13,681,533	Internal chloride concentration and chloride efflux of frog muscle.	J Physiol	1961	https://conductscience.org/library/papers/13681533	PubMed
10	4,472,159	Intracellular bicarbonate in single skeletal muscle fibers.	Pflugers Arch	1974	https://conductscience.org/library/papers/4472159	PubMed
11	14,082,127	CHLORIDE IN THE SQUID GIANT AXON.	J Physiol	1963	https://conductscience.org/library/papers/14082127	PubMed
12	13,791,936	Potassium chloride movement and the membrane potential of frog muscle.	J Physiol	1960	https://conductscience.org/library/papers/13791936	PubMed
13	4,253,930	Intracellular pH and buffering power of rat muscle.	Am J Physiol	1971	https://conductscience.org/library/papers/4253930	PubMed
14	14,402,240	The influence of potassium and chloride ions on the membrane potential of single muscle fibres.	J Physiol	1959	https://conductscience.org/library/papers/14402240	PubMed
15	4,536,964	Intracellular pH, H ion flux and H ion permeability coefficient in bullfrog toe muscle.	J Physiol	1972	https://conductscience.org/library/papers/4536964	PubMed
17	12,472	Role of choloride transport in regulation of intracellular pH.	Nature	1976	https://conductscience.org/library/papers/12472	PubMed
18	4,715,371	New design for a chloride-sensitive micro-electrode.	J Physiol	1973	https://conductscience.org/library/papers/4715371	PubMed
20	13,758,423	The chloride content of rat auricle.	J Physiol	1961	https://conductscience.org/library/papers/13758423	PubMed
21	4,419,403	Proceedings: Measurement of chloride activity within frog sartorius muscle fibres by means of chloride-sensitive micro-electrodes.	J Physiol	1974	https://conductscience.org/library/papers/4419403	PubMed
22	978,554	The use of electrodes containing liquid ion-sensitive resin to measure the intracellular chloride activity of skeletal muscle [proceedings].	J Physiol	1976	https://conductscience.org/library/papers/978554	PubMed
23	4,539,587	The voltage dependence of the chloride conductance of frog muscle.	J Physiol	1972	https://conductscience.org/library/papers/4539587	PubMed

Show 14 more referencesShow fewer referencesSee all 31 references

Cited by55

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 104 citations.

PMID	Title	Journal	Year	In Papers	Source
33,328,894	Horizontal Cell Feedback to Cone Photoreceptors in Mammalian Retina: Novel Insights From the GABA-pH Hybrid Model.	Front Cell Neurosci	2020	https://conductscience.org/library/papers/33328894	PubMed
31,827,130	A highly-selective chloride microelectrode based on a mercuracarborand anion carrier.	Sci Rep	2019	https://conductscience.org/library/papers/31827130	PubMed
28,320,898	A personal historic perspective on the role of chloride in skeletal and cardiac muscle.	Physiol Rep	2017	https://conductscience.org/library/papers/28320898	PubMed
27,022,190	Role of physiological ClC-1 Cl- ion channel regulation for the excitability and function of working skeletal muscle.	J Gen Physiol	2016	https://conductscience.org/library/papers/27022190	PubMed
24,965,587	Evidence from simultaneous intracellular- and surface-pH transients that carbonic anhydrase II enhances CO2 fluxes across Xenopus oocyte plasma membranes.	Am J Physiol Cell Physiol	2014	https://conductscience.org/library/papers/24965587	PubMed
23,577,101	Regulation of ion gradients across myocardial ischemic border zones: a biophysical modelling analysis.	PLoS One	2013	https://conductscience.org/library/papers/23577101	PubMed
8,738,302	Chloride current in toad skeletal muscle and its modification by the histidine-modifying reagent diethylpyrocarbonate.	Naunyn Schmiedebergs Arch Pharmacol	1996	https://conductscience.org/library/papers/8738302	PubMed
8,487,196	31P nuclear magnetic resonance studies on the glycogenolysis regulation in resting and contracting frog skeletal muscle.	J Physiol	1993	https://conductscience.org/library/papers/8487196	PubMed
8,189,392	Endogenous Na(+)-K+ (or NH4+)-2Cl- cotransport in Rana oocytes; anomalous effect of external NH4+ on pHi.	J Physiol	1994	https://conductscience.org/library/papers/8189392	PubMed
7,411,434	Chloride efflux in single barnacle muscle fibres.	J Physiol	1980	https://conductscience.org/library/papers/7411434	PubMed
7,108,787	Measurement of intracellular chloride in guinea-pig vas deferens by ion analysis, 36chloride efflux and micro-electrodes.	J Physiol	1982	https://conductscience.org/library/papers/7108787	PubMed
6,984,069	Optical measurements of intracellular pH and magnesium in frog skeletal muscle fibres.	J Physiol	1982	https://conductscience.org/library/papers/6984069	PubMed
6,966,688	Mechanical relaxation rate and metabolism studied in fatiguing muscle by phosphorus nuclear magnetic resonance.	J Physiol	1980	https://conductscience.org/library/papers/6966688	PubMed
6,887,045	Modification of potassium movement through the retina of the drone (Apis mellifera male) by glial uptake.	J Physiol	1983	https://conductscience.org/library/papers/6887045	PubMed
6,875,906	Towards an estimate of chloride permeability in the smooth muscle of guinea-pig vas deferens.	J Physiol	1983	https://conductscience.org/library/papers/6875906	PubMed
6,839,064	Neuronal influence on the mechanical activity of the ciliary muscle.	Br J Pharmacol	1983	https://conductscience.org/library/papers/6839064	PubMed
6,776,259	Carbon dioxide, membrane potential and intracellular potassium activity in frog skeletal muscle.	J Physiol	1980	https://conductscience.org/library/papers/6776259	PubMed
6,752,417	Transport of electrolytes in muscle.	J Membr Biol	1982	https://conductscience.org/library/papers/6752417	PubMed
6,492,131	Intracellular chloride activity in the extensor digitorum longus (EDL) muscle of the rat.	J Membr Biol	1984	https://conductscience.org/library/papers/6492131	PubMed
6,420,546	The intracellular pH of frog skeletal muscle: its regulation in isotonic solutions.	J Physiol	1983	https://conductscience.org/library/papers/6420546	PubMed

Show 14 more cited byShow fewer cited bySee all 55 cited by

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

None in this release

Grants
Trials
Comments and corrections
Genes
Drugs
Data

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this paper from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/papers/v1/20501

GET https://conductscience.org/api/papers/v1/20501/references?page=2

API reference For AI assistants