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Paper21157

Regulatory mutations in the Klebsiella aerogenes structural gene for glutamine synthetase.

Bender RA and 1 other. J Bacteriol, 1977. Cited by 48 papers, by iCite.

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ConductScience Library. Regulatory mutations in the Klebsiella aerogenes structural gene for glutamine synthetase. Papers, record 21157. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/21157

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Regulatory mutations in the Klebsiella aerogenes structural gene for glutamine synthetase.
PubMed
Journal
J Bacteriol
PubMed
Year
1977
PubMed
Publication types
Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
48
iCite
Relative citation ratio, by iCite
1.44
iCite
Revised in PubMed
2021-05-26
PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Bender RAR A
2Magasanik BB

Source PubMed

Topics8

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
GenesMajor topic
Glutamate-Ammonia LigaseMajor topic
Klebsiella pneumoniaeMajor topic
MutationMajor topic
Ammonia
Enzyme Repression
Glutamine
Histidine

Source PubMed

References27

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
114,104Biochemical parameters of glutamine synthetase from Klebsiella aerogenes.J Bacteriol1977https://conductscience.org/library/papers/14104PubMed
214,117Glutamine synthetase of Klebsiella aerogenes: genetic and physiological properties of mutants in the adenylylation system.J Bacteriol1977https://conductscience.org/library/papers/14117PubMed
41,744Regulation of synthesis of glutamine synthetase by adenylylated glutamine synthetase.Proc Natl Acad Sci U S A1975https://conductscience.org/library/papers/1744PubMed
518,438Urease of Klebsiella aerogenes: control of its synthesis by glutamine synthetase.J Bacteriol1977https://conductscience.org/library/papers/18438PubMed
621,158Autogenous regulation of the synthesis of glutamine synthetase in Klebsiella aerogenes.J Bacteriol1977https://conductscience.org/library/papers/21158PubMed
7234,938Identification of the structural gene for glutamine synthetase in Klebsiella aerogenes.J Bacteriol1975https://conductscience.org/library/papers/234938PubMed
8234,939Genetic control of glutamine synthetase in Klebiella aerogenes.J Bacteriol1975https://conductscience.org/library/papers/234939PubMed
9238,954Regulation of nitrogen metabolism in Escherichia coli and Klebsiella aerogenes: studies with the continuous-culture technique.J Bacteriol1975https://conductscience.org/library/papers/238954PubMed
10240,804Regulation of the ammonia assimilatory enzymes in Salmonella typhimurium.J Bacteriol1975https://conductscience.org/library/papers/240804PubMed
114,145,197Effect of methionine sulfoximine and methionine sulfone on glutamate synthesis in Klebsiella aerogenes.J Bacteriol1973https://conductscience.org/library/papers/4145197PubMed
124,145,798Glutamine synthetase and the regulation of histidase formation in Klebsiella aerogenes.J Biol Chem1973https://conductscience.org/library/papers/4145798PubMed
134,146,916Regulation of the synthesis of enzymes responsible for glutamate formation in Klebsiella aerogenes.J Biol Chem1973https://conductscience.org/library/papers/4146916PubMed
144,149,344Activation of transcription of hut DNA by glutamine synthetase.Proc Natl Acad Sci U S A1974https://conductscience.org/library/papers/4149344PubMed
154,153,588Glutamine synthetase and ammonium regulation of nitrogenase synthesis in Klebsiella.Nature1974https://conductscience.org/library/papers/4153588PubMed
164,153,589Glutamine synthetase as a regulator of enzyme synthesis.Curr Top Cell Regul1974https://conductscience.org/library/papers/4153589PubMed
174,156,359Regulation of nitrogen fixation in Klebsiella pneumoniae: evidence for a role of glutamine synthetase as a regulator of nitrogenase synthesis.J Bacteriol1974https://conductscience.org/library/papers/4156359PubMed
184,331,387Resistance to catabolite repression of histidase and proline oxidase during nitrogen-limited growth of Klebsiella aerogenes.J Biol Chem1971https://conductscience.org/library/papers/4331387PubMed
194,459L-Asparaginase of Klebsiella aerogenes. Activation of its synthesis by glutamine synthetase.J Biol Chem1976https://conductscience.org/library/papers/4459PubMed
204,598,005Direct selection for P1-sensitive mutants of enteric bacteria.J Bacteriol1974https://conductscience.org/library/papers/4598005PubMed
214,606,417Derepression of nitrogenase synthesis in the presence of excess NH4+.Biochem Biophys Res Commun1974https://conductscience.org/library/papers/4606417PubMed

See all 27 references

Cited by37

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 48 citations.

PMIDTitleJournalYearIn PapersSource
24,255,125Nitrogen and carbon status are integrated at the transcriptional level by the nitrogen regulator NtrC in vivo.mBio2013https://conductscience.org/library/papers/24255125PubMed
23,925,119Coordination of bacterial proteome with metabolism by cyclic AMP signalling.Nature2013https://conductscience.org/library/papers/23925119PubMed
23,546,877The molecular basis of K+ exclusion by the Escherichia coli ammonium channel AmtB.J Biol Chem2013https://conductscience.org/library/papers/23546877PubMed
22,933,560Regulation of the histidine utilization (hut) system in bacteria.Microbiol Mol Biol Rev2012https://conductscience.org/library/papers/22933560PubMed
21,775,672The pivotal twin histidines and aromatic triad of the Escherichia coli ammonium channel AmtB can be replaced.Proc Natl Acad Sci U S A2011https://conductscience.org/library/papers/21775672PubMed
20,675,498A NAC for regulating metabolism: the nitrogen assimilation control protein (NAC) from Klebsiella pneumoniae.J Bacteriol2010https://conductscience.org/library/papers/20675498PubMed
20,348,267Expanded role for the nitrogen assimilation control protein in the response of Klebsiella pneumoniae to nitrogen stress.J Bacteriol2010https://conductscience.org/library/papers/20348267PubMed
16,592,892Regulation of Rhizobium nitrogen fixation by the unadenylylated glutamine synthetase I system.Proc Natl Acad Sci U S A1980https://conductscience.org/library/papers/16592892PubMed
12,010,975A glutamine transport gene, glnQ, is required for fibronectin adherence and virulence of group B streptococci.Infect Immun2002https://conductscience.org/library/papers/12010975PubMed
11,673,431Roles of glutamate synthase, gltBD, and gltF in nitrogen metabolism of Escherichia coli and Klebsiella aerogenes.J Bacteriol2001https://conductscience.org/library/papers/11673431PubMed
8,458,854The product of the Klebsiella aerogenes nac (nitrogen assimilation control) gene is sufficient for activation of the hut operons and repression of the gdh operon.J Bacteriol1993https://conductscience.org/library/papers/8458854PubMed
8,419,283Autogenous regulation of gene expression.J Bacteriol1993https://conductscience.org/library/papers/8419283PubMed
7,035,832Glutamine auxotrophs with mutations in a nitrogen regulatory gene, ntrC, that is near glnA.Mol Gen Genet1981https://conductscience.org/library/papers/7035832PubMed
6,139,739Regulation of transcription of glnA, the structural gene encoding glutamine synthetase, in glnA::Mu d1 (ApR, lac) fusion strains of Salmonella typhimurium.Mol Gen Genet1983https://conductscience.org/library/papers/6139739PubMed
6,134,228Nucleotide sequence of the glnA control region of Escherichia coli.Mol Gen Genet1983https://conductscience.org/library/papers/6134228PubMed
6,129,565A nonsense mutation in the structural gene for glutamine synthetase leading to loss of nitrogen regulation in Klebsiella aerogenes.Mol Gen Genet1982https://conductscience.org/library/papers/6129565PubMed
6,122,676Fine-structure deletion map and complementation analysis of the glnA-glnL-glnG region in Escherichia coli.J Bacteriol1982https://conductscience.org/library/papers/6122676PubMed
6,120,931Role of glnA-linked genes in regulation of glutamine synthetase and histidase formation in Klebsiella aerogenes.J Bacteriol1982https://conductscience.org/library/papers/6120931PubMed
6,120,930Characterization of a gene, glnL, the product of which is involved in the regulation of nitrogen utilization in Escherichia coli.J Bacteriol1982https://conductscience.org/library/papers/6120930PubMed
6,120,929Complex glnA-glnL-glnG operon of Escherichia coli.J Bacteriol1982https://conductscience.org/library/papers/6120929PubMed

See all 37 cited by

Genes1

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn Genes
GLUL2,752PubTator's text mininghttps://conductscience.org/library/genes/2752

Source NCBI Gene

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

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  • PMC's ID filePublic domain (US government)
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  • UniProtCC BY 4.0
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  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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