Paper · 21304

Nonstructural proteins of herpes simplex virus. I. Purification of the induced DNA polymerase.

Powell KL and 1 other. J Virol, 1977. Cited by 160 papers, by iCite.

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ConductScience Library. Nonstructural proteins of herpes simplex virus. I. Purification of the induced DNA polymerase. Papers, record 21304. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/21304

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Nonstructural proteins of herpes simplex virus. I. Purification of the induced DNA polymerase.; PubMed
Journal: J Virol; PubMed
Year: 1977; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/21304/; PubMed
DOI: https://doi.org/10.1128/jvi.24.2.618-626.1977; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC515973/; PubMed
The journal: https://conductscience.org/library/journal-index/0113724; PubMed
Citations, by iCite: 160; iCite
Relative citation ratio, by iCite: 3.94; iCite
Revised in PubMed: 2020-07-24; PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	Kind	ORCID iD
1	Powell KL	K L
2	Purifoy DJ	D J

Source PubMed

Topics11

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Bacterial Proteins	Major topic
DNA-Directed DNA Polymerase	Major topic
Simplexvirus	Major topic
Antibodies, Viral
Cell Line
Deoxyribonucleases
Enzyme Induction
Hydrogen-Ion Concentration
Magnesium
Neutralization Tests
Phosphonoacetic Acid

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References22

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	13,532	Purification and characterization of equine herpesvirus-induced DNA.	Virology	1977	https://conductscience.org/library/papers/13532	PubMed
2	165,503	Regulation of herpesvirus macromolecular synthesis: sequential transition of polypeptide synthesis requires functional viral polypeptides.	Proc Natl Acad Sci U S A	1975	https://conductscience.org/library/papers/165503	PubMed
3	166,500	Polypeptide synthesized in herpes simplex virus type 2-infected HEp-2 cells.	Virology	1975	https://conductscience.org/library/papers/166500	PubMed
4	169,027	Genetic and biochemical studies with herpesvirus.	Cold Spring Harb Symp Quant Biol	1975	https://conductscience.org/library/papers/169027	PubMed
5	172,894	Possible peptide chain termination mutants in thymide kinase gene of a mammalian virus, herpes simplex virus.	Proc Natl Acad Sci U S A	1975	https://conductscience.org/library/papers/172894	PubMed
6	173,076	DNA polymerase induction by DNA-negative temperature-sensitive mutants of herpes simplex virus type 2.	Virology	1975	https://conductscience.org/library/papers/173076	PubMed
7	183,021	DNA-binding proteins induced by herpes simplex virus type 2 in HEp-2 cells.	J Virol	1976	https://conductscience.org/library/papers/183021	PubMed
8	187,552	Comparison of DNA polymerase activities induced by herpes simplex virus types 1 and 2.	Intervirology	1975	https://conductscience.org/library/papers/187552	PubMed
9	189,089	Herpes simplex virus resistance and sensitivity to phosphonoacetic acid.	J Virol	1977	https://conductscience.org/library/papers/189089	PubMed
10	192,691	Comparative analysis of polypeptides induced by type 1 and type 2 strains of herpes simplex virus.	Intervirology	1977	https://conductscience.org/library/papers/192691	PubMed

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Cited by62

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 160 citations.

PMID	Title	Journal	Year	In Papers	Source
8,627,723	Herpes simplex ICP27 mutant viruses exhibit reduced expression of specific DNA replication genes.	J Virol	1996	https://conductscience.org/library/papers/8627723	PubMed
8,437,207	Functional analysis of the herpes simplex virus UL42 protein.	J Virol	1993	https://conductscience.org/library/papers/8437207	PubMed
8,383,221	Deletions of the carboxy terminus of herpes simplex virus type 1 UL42 define a conserved amino-terminal functional domain.	J Virol	1993	https://conductscience.org/library/papers/8383221	PubMed
8,382,792	Sequences at the C-terminus of the herpes simplex virus type 1 UL30 protein are dispensable for DNA polymerase activity but not for viral origin-dependent DNA replication.	Nucleic Acids Res	1993	https://conductscience.org/library/papers/8382792	PubMed
8,380,085	The extreme C terminus of herpes simplex virus DNA polymerase is crucial for functional interaction with processivity factor UL42 and for viral replication.	J Virol	1993	https://conductscience.org/library/papers/8380085	PubMed
8,035,492	Interaction of herpes simplex virus type 1 DNA polymerase and the UL42 accessory protein with a model primer template.	J Virol	1994	https://conductscience.org/library/papers/8035492	PubMed
7,944,949	Identification of mutation sites of a temperature-sensitive mutant of HCMV DNA polymerase activity.	Arch Virol	1994	https://conductscience.org/library/papers/7944949	PubMed
6,321,775	Characterization of the major mRNAs transcribed from the genes for glycoprotein B and DNA-binding protein ICP8 of herpes simplex virus type 1.	J Virol	1984	https://conductscience.org/library/papers/6321775	PubMed
6,317,891	Fine mapping and molecular cloning of mutations in the herpes simplex virus DNA polymerase locus.	J Virol	1984	https://conductscience.org/library/papers/6317891	PubMed
6,313,961	High-resolution characterization of herpes simplex virus type 1 transcripts encoding alkaline exonuclease and a 50,000-dalton protein tentatively identified as a capsid protein.	J Virol	1983	https://conductscience.org/library/papers/6313961	PubMed

1 to 10 of 62

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None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

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None in this release.

Data dates

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PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

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ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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