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Paper · 218201

In vitro suppression of UAG and UGA mutants in the thymidine kinase gene of herpes simplex virus.

Cremer KJ and 4 others. Proc Natl Acad Sci U S A, 1979. Cited by 36 papers, by iCite.

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ConductScience Library. In vitro suppression of UAG and UGA mutants in the thymidine kinase gene of herpes simplex virus. Papers, record 218201. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/218201

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
In vitro suppression of UAG and UGA mutants in the thymidine kinase gene of herpes simplex virus.
PubMed
Journal
Proc Natl Acad Sci U S A
PubMed
Year
1979
PubMed
Publication types
Journal Article, Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
36
iCite
Relative citation ratio, by iCite
0.9
iCite
Revised in PubMed
2019-05-01
PubMed

Authors5

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Cremer KJK J
2Bodemer MM
3Summers WPW P
4Summers WCW C
5Gesteland RFR F

Source PubMed

Topics9

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
GenesMajor topic
SimplexvirusMajor topic
Suppression, GeneticMajor topic
Thymidine KinaseMajor topic
Cell-Free System
Codon
Mutation
RNA, Transfer
Saccharomyces cerevisiae

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References14

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
11,035,137The 3' terminal sequences of human alpha and beta globin messenger RNAs: comparison with rabbit globin messenger RNA.Cell1976https://conductscience.org/library/papers/1035137PubMed
2198,667Identification of a transformation-specific antigen induced by an avian sarcoma virus.Nature1977https://conductscience.org/library/papers/198667PubMed
3198,581[125I]deoxycytidine used in a rapid, sensitive, and specific assay for herpes simplex virus type 1 thymidine kinase.J Virol1977https://conductscience.org/library/papers/198581PubMed
4209,407Characterization of the mRNA for herpes simplex virus thymidine kinase by cell-free synthesis of active enzyme.Nucleic Acids Res1978https://conductscience.org/library/papers/209407PubMed
5200,921Identification of amber and ochre mutants of the human virus Ad2+ND1.Proc Natl Acad Sci U S A1977https://conductscience.org/library/papers/200921PubMed
6202,399Translation of MuLV and MSV RNAs in nuclease-treated reticulocyte extracts: enhancement of the gag-pol polypeptide with yeast suppressor tRNA.Cell1978https://conductscience.org/library/papers/202399PubMed
7195,089Cell-free synthesis of herpes simplex virus proteins.J Virol1977https://conductscience.org/library/papers/195089PubMed
8634,374Leaky UAG termination codon in tobacco mosaic virus RNA.Nature1978https://conductscience.org/library/papers/634374PubMed
9912,748The isolation of a suppressible nonsense mutant in mammalian cells.Cell1977https://conductscience.org/library/papers/912748PubMed
10823,012An efficient mRNA-dependent translation system from reticulocyte lysates.Eur J Biochem1976https://conductscience.org/library/papers/823012PubMed

Cited by20

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 36 citations.

PMIDTitleJournalYearIn PapersSource
33,567,469Therapeutic promise of engineered nonsense suppressor tRNAs.Wiley Interdiscip Rev RNA2021https://conductscience.org/library/papers/33567469PubMed
7,049,160Informational suppression as a tool for the investigation of gene structure and function.Biochem J1982https://conductscience.org/library/papers/7049160PubMed
7,024,919Usage of the three termination codons in a single eukaryotic cell, the Xenopus laevis oocyte.Nucleic Acids Res1981https://conductscience.org/library/papers/7024919PubMed
6,328,014Cooperative effects between two acyclovir resistance loci in herpes simplex virus.J Virol1984https://conductscience.org/library/papers/6328014PubMed
6,312,072Functional suppression in mammalian cells of nonsense mutations in the herpes simplex virus thymidine kinase gene by suppressor tRNA genes.J Virol1983https://conductscience.org/library/papers/6312072PubMed
6,310,546An amber suppressor tRNA gene derived by site-specific mutagenesis: cloning and function in mammalian cells.Proc Natl Acad Sci U S A1982https://conductscience.org/library/papers/6310546PubMed
6,290,987Expression of a X. laevis tRNATyr gene in mammalian cells.Nucleic Acids Res1982https://conductscience.org/library/papers/6290987PubMed
6,264,137Translational products of Moloney murine sarcoma virus RNA: identification of proteins encoded by the murine sarcoma virus src gene.J Virol1981https://conductscience.org/library/papers/6264137PubMed
6,262,799Nucleotide sequence of the thymidine kinase gene of herpes simplex virus type 1.Proc Natl Acad Sci U S A1981https://conductscience.org/library/papers/6262799PubMed
6,258,156The nucleotide sequence and transcript map of the herpes simplex virus thymidine kinase gene.Nucleic Acids Res1980https://conductscience.org/library/papers/6258156PubMed

1 to 10 of 20

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Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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