Paper · 2200519

Kinetics of interaction of nucleotides with nucleotide-free H-ras p21.

John J and 5 others. Biochemistry, 1990. Cited by 407 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

Cite this record

ConductScience Library. Kinetics of interaction of nucleotides with nucleotide-free H-ras p21. Papers, record 2200519. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/2200519

On this page

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Kinetics of interaction of nucleotides with nucleotide-free H-ras p21.; PubMed
Journal: Biochemistry; PubMed
Year: 1990; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/2200519/; PubMed
DOI: https://doi.org/10.1021/bi00477a025; PubMed
The journal: https://conductscience.org/library/journal-index/0370623; PubMed
Citations, by iCite: 407; iCite
Relative citation ratio, by iCite: 6.93; iCite
Revised in PubMed: 2019-06-13; PubMed

Authors6

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	John J	J
2	Sohmen R	R
3	Feuerstein J	J
4	Linke R	R
5	Wittinghofer A	A
6	Goody RS	R S

Source PubMed

Topics8

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Nucleotides	Major topic
Oncogene Protein p21(ras)	Major topic
Guanosine
Guanosine Diphosphate
Guanosine Triphosphate
Kinetics
Spectrometry, Fluorescence
ortho-Aminobenzoates

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

None in this release.

Cited by158

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 407 citations.

PMID	Title	Journal	Year	In Papers	Source
42,144,822	Use of tandem-affinity chromatography to incorporate nucleotide loading of small GTPases during their purification.	Protein Sci	2026	https://conductscience.org/library/papers/42144822	PubMed
42,105,364	Mechanistic insights on spatiotemporal control of Ras-signaling.	Biol Chem	2026	https://conductscience.org/library/papers/42105364	PubMed
41,637,523	Kras G12C- and G12D-driven lung cancers differ in oncogenic potency, immunogenicity, and relapse after Kras inhibition in mouse models.	Sci Transl Med	2026	https://conductscience.org/library/papers/41637523	PubMed
41,438,133	A KRASG12V-targeted bispecific T cell engager promotes immunity against colorectal solid tumor.	Mol Ther Oncol	2025	https://conductscience.org/library/papers/41438133	PubMed
41,418,323	Mechanistic insights into Ras-catalyzed GTP hydrolysis: conformational dynamics, catalytic mechanisms, and emerging therapeutic strategies.	Biol Chem	2026	https://conductscience.org/library/papers/41418323	PubMed
41,042,129	IMPDH and GTP Metabolism in Cancer: Mechanisms, Regulation, and Translational Scope.	Cancer Sci	2025	https://conductscience.org/library/papers/41042129	PubMed
40,936,333	Identification of Small-Molecule Inhibitors that Block the GTP-Binding Pocket of K-Ras and Other Members of the Ras Superfamily of Small GTPases.	Mol Cancer Ther	2026	https://conductscience.org/library/papers/40936333	PubMed
40,918,036	Distinct association of HRAS and KRAS with Mn2+ ion illustrated by paramagnetic NMR.	Magn Reson Lett	2025	https://conductscience.org/library/papers/40918036	PubMed
40,396,811	Methods for Controlling Small GTPase Activity.	Chembiochem	2025	https://conductscience.org/library/papers/40396811	PubMed
40,226,972	Nondegradative Synthetic Molecular Glues Enter the Clinic.	ChemMedChem	2025	https://conductscience.org/library/papers/40226972	PubMed

1 to 10 of 158

See all 158 cited by

Genes2

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes	Source
H3P16	644,914	PubTator's text mining	https://conductscience.org/library/genes/644914	NCBI Gene
HRAS	3,265	PubTator's text mining	https://conductscience.org/library/genes/3265	NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this paper from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/papers/v1/2200519

GET https://conductscience.org/api/papers/v1/2200519/cited_by?page=2

API reference For AI assistants