Paper · 22013552

Cytokine-induced alterations of gastrointestinal motility in gastrointestinal disorders.

Akiho H and 3 others. World J Gastrointest Pathophysiol, 2011. Cited by 96 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Cytokine-induced alterations of gastrointestinal motility in gastrointestinal disorders. Papers, record 22013552. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/22013552

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Cytokine-induced alterations of gastrointestinal motility in gastrointestinal disorders.; PubMed
Journal: World J Gastrointest Pathophysiol; PubMed
Year: 2011; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/22013552/; PubMed
DOI: https://doi.org/10.4291/wjgp.v2.i5.72; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC3196622/; PubMed
The journal: https://conductscience.org/library/journal-index/101547471; PubMed
Citations, by iCite: 96; iCite
Relative citation ratio, by iCite: 2.93; iCite
Revised in PubMed: 2021-10-20; PubMed

Authors4

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Akiho H	Hirotada
2	Ihara E	Eikichi
3	Motomura Y	Yasuaki
4	Nakamura K	Kazuhiko

Source PubMed

Topics0

NLM's MeSH indexing of the paper, its major topics first.

None in this release.

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References111

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	18,438,405	Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis.	Nat Genet	2008	https://conductscience.org/library/papers/18438405	PubMed
2	20,704,730	The inflammatory cytokine tumor necrosis factor modulates the expression of Salmonella typhimurium effector proteins.	J Inflamm (Lond)	2010	https://conductscience.org/library/papers/20704730	PubMed
3	12,145,795	Serotonin-transporter polymorphism pharmacogenetics in diarrhea-predominant irritable bowel syndrome.	Gastroenterology	2002	https://conductscience.org/library/papers/12145795	PubMed
4	20,016,839	Th17: a new participant in gut dysfunction in mice infected with Trichinella spiralis.	Mediators Inflamm	2009	https://conductscience.org/library/papers/20016839	PubMed
5	11,729,115	Prostanoid production via COX-2 as a causative mechanism of rodent postoperative ileus.	Gastroenterology	2001	https://conductscience.org/library/papers/11729115	PubMed
6	12,360,482	Immune-mediated neural dysfunction in a murine model of chronic Helicobacter pylori infection.	Gastroenterology	2002	https://conductscience.org/library/papers/12360482	PubMed
7	10,073,262	Intestinal pseudo-obstruction.	Annu Rev Med	1999	https://conductscience.org/library/papers/10073262	PubMed
8	12,454,854	Full-thickness biopsy of the jejunum reveals inflammation and enteric neuropathy in irritable bowel syndrome.	Gastroenterology	2002	https://conductscience.org/library/papers/12454854	PubMed
9	1,566,844	Abdominal surgery-induced delayed gastric emptying in rats: role of CRF and sensory neurons.	Am J Physiol	1992	https://conductscience.org/library/papers/1566844	PubMed
10	16,143,135	Interleukin-22, a member of the IL-10 subfamily, induces inflammatory responses in colonic subepithelial myofibroblasts.	Gastroenterology	2005	https://conductscience.org/library/papers/16143135	PubMed

1 to 10 of 111

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Cited by64

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 96 citations.

PMID	Title	Journal	Year	In Papers	Source
42,769,358	Acteoside alleviates slow transit constipation with attenuation of NLRP3 inflammasome activation and preservation of enteric neurons.	Front Pharmacol	2026	https://conductscience.org/library/papers/42769358	PubMed
42,504,649	Advances in Understanding Calcium Sensitization in Gastrointestinal Smooth Muscles: Pathways, Interstitial Cells, and Disease.	J Neurogastroenterol Motil	2026	https://conductscience.org/library/papers/42504649	PubMed
42,420,720	The Convergence of Ancient Medical Wisdom and Modern Physiology: Sodium Ion Wave Propagation in Endothelial Cells, IL-1 Vascular Pathways, and the Six-Day Progression Pattern of Clinical Symptoms.	Adv Exp Med Biol	2026	https://conductscience.org/library/papers/42420720	PubMed
42,371,203	A case of suspected vertical hepatozoonosis manifesting as severe anemia and gastroenteritis in a three-month-old puppy following vaccination.	Vet Res Commun	2026	https://conductscience.org/library/papers/42371203	PubMed
42,291,191	Neuronal responses to cytokines limit intestinal hypermotility and systemic effects of colonic inflammation.	iScience	2026	https://conductscience.org/library/papers/42291191	PubMed
41,798,890	Macrophage Immune-Competent Colon Assembloids for Functional Interrogation of Neuroinflammation-Induced Colonic Dysmotility.	Gastro Hep Adv	2026	https://conductscience.org/library/papers/41798890	PubMed
41,683,005	Lactiplantibacillus plantarum LPPerfectus001 Alleviating Irritable Bowel Syndrome in Mice by Modulating Gut Microbiota and NF-κB Signaling Pathway.	Foods	2026	https://conductscience.org/library/papers/41683005	PubMed
41,612,972	Muribaculum intestinale negatively impacts glioma growth in mice through the toll-like receptor 2.	Gut Microbes	2026	https://conductscience.org/library/papers/41612972	PubMed
41,572,371	Biomarkers and immunomodulatory effect of erythropoietin in postoperative ileus.	BMC Res Notes	2026	https://conductscience.org/library/papers/41572371	PubMed
40,835,780	Gastrointestinal symptoms are common in patients with new-onset refractory status epilepticus (NORSE).	Neurol Sci	2025	https://conductscience.org/library/papers/40835780	PubMed

1 to 10 of 64

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Genes2

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes	Source
PPP1R14A	94,274	PubTator's text mining	https://conductscience.org/library/genes/94274	NCBI Gene
STAT6	6,778	PubTator's text mining	https://conductscience.org/library/genes/6778	NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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