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Paper · 221908

Solubilized and insolubilized bone morphogenetic protein.

Urist MR and 2 others. Proc Natl Acad Sci U S A, 1979. Cited by 421 papers, by iCite.

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ConductScience Library. Solubilized and insolubilized bone morphogenetic protein. Papers, record 221908. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/221908

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Solubilized and insolubilized bone morphogenetic protein.
PubMed
Journal
Proc Natl Acad Sci U S A
PubMed
Year
1979
PubMed
Publication types
Journal Article, Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
421
iCite
Relative citation ratio, by iCite
12.8
iCite
Revised in PubMed
2019-05-01
PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Urist MRM R
2Mikulski AA
3Lietze AA

Source PubMed

Topics8

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Bone and BonesMajor topic
ProteinsMajor topic
Animals
Biological Assay
Microbial Collagenase
Protein Conformation
Rabbits
Solubility

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References28

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
113,692,073The determination of amino sugars in the presence of amino acids and glucose.Biochem J1960https://conductscience.org/library/papers/13692073PubMed
2689,705Cartilage tissue differentiation from mesenchymal cells derived from mature muscle in tissue culture.In Vitro1978https://conductscience.org/library/papers/689705PubMed
3202,375Methods for the study of the glycoproteins and proteoglycans of bone using bacterial collagenase. Determination of bone sialoprotein and chondroitin sulphate.Calcif Tissue Res1977https://conductscience.org/library/papers/202375PubMed
4188,411A comparison of bone matrix and tendon with particular reference to glycoprotein content.Biochem J1976https://conductscience.org/library/papers/188411PubMed
5653,353The hydrophobic effect and the organization of living matter.Science1978https://conductscience.org/library/papers/653353PubMed
6880,293Purification and characterization of a peptide from the carboxy-terminal region of chick tendon procollagen type I.Biochemistry1977https://conductscience.org/library/papers/880293PubMed
7857,763Transmembrane bone morphogenesis across multiple-walled diffusion chambers. New evidence for a diffusible bone morphogenetic property.Arch Surg1977https://conductscience.org/library/papers/857763PubMed
84,368,850Isolation and partial characterization of a glycoprotein from bovine cortical bone.Eur J Biochem1974https://conductscience.org/library/papers/4368850PubMed
94,359,104Studies on bone matrix glycoproteins. Incorporation of (1-14C)glucosamine and plasma (14C)glycoprotein into rabbit cortical bone.Biochem J1973https://conductscience.org/library/papers/4359104PubMed
104,357,876Bone morphogenesis in implants of insoluble bone gelatin.Proc Natl Acad Sci U S A1973https://conductscience.org/library/papers/4357876PubMed

1 to 10 of 28

See all 28 references

Cited by78

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 421 citations.

PMIDTitleJournalYearIn PapersSource
41,273,147Growth and Developmental Processes Alternate During Larval Development of Atlantic Herring.Evol Dev2025https://conductscience.org/library/papers/41273147PubMed
38,891,449Experimental Study on Rats with Critical-Size Bone Defects Comparing Effects of Autologous Bone Graft, Equine Bone Substitute Bio-Gen® Alone or in Association with Platelet-Rich Fibrin (PRF).Polymers (Basel)2024https://conductscience.org/library/papers/38891449PubMed
38,819,709p200CUX1-regulated BMP8B inhibits the progression of acute myeloid leukemia via the MAPK signaling pathway.Med Oncol2024https://conductscience.org/library/papers/38819709PubMed
36,109,564Induction of functional xeno-free MSCs from human iPSCs via a neural crest cell lineage.NPJ Regen Med2022https://conductscience.org/library/papers/36109564PubMed
35,856,444BMP2 inhibits cell proliferation by downregulating EZH2 in gastric cancer.Cell Cycle2022https://conductscience.org/library/papers/35856444PubMed
34,031,510Functional interaction between Wnt and Bmp signaling in periosteal bone growth.Sci Rep2021https://conductscience.org/library/papers/34031510PubMed
33,745,185BMP/TGF-β signaling as a modulator of neurodegeneration in ALS.Dev Dyn2022https://conductscience.org/library/papers/33745185PubMed
33,396,904Heterotopic Ossification of the Vascular Pedicle after Maxillofacial Reconstructive Surgery Using Fibular Free Flap: Introducing New Classification and Retrospective Analysis.J Clin Med2020https://conductscience.org/library/papers/33396904PubMed
32,508,545New Strategies in Enhancing Spinal Fusion.HSS J2020https://conductscience.org/library/papers/32508545PubMed
32,053,985Bu-M-P-ing Iron: How BMP Signaling Regulates Muscle Growth and Regeneration.J Dev Biol2020https://conductscience.org/library/papers/32053985PubMed

1 to 10 of 78

See all 78 cited by

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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