Paper · 23636699

No evidence for cumulative effects in a Dnmt3b hypomorph across multiple generations.

Youngson NA and 12 others. Mamm Genome, 2013. Cited by 10 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. No evidence for cumulative effects in a Dnmt3b hypomorph across multiple generations. Papers, record 23636699. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/23636699

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: No evidence for cumulative effects in a Dnmt3b hypomorph across multiple generations.; PubMed
Journal: Mamm Genome; PubMed
Year: 2013; PubMed
Publication types: Journal Article, Research Support, Non-U.S. Gov't; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/23636699/; PubMed
DOI: https://doi.org/10.1007/s00335-013-9451-5; PubMed
The journal: https://conductscience.org/library/journal-index/9100916; PubMed
Citations, by iCite: 10; iCite
Relative citation ratio, by iCite: 0.21; iCite
Revised in PubMed: 2026-01-28; PubMed

Authors13

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Youngson NA	Neil A
2	Epp T	Trevor
3	Roberts AR	Amity R
4	Daxinger L	Lucia
5	Ashe A	Alyson
6	Huang E	Edward
7	Lester KL	Krystal L
8	Harten SK	Sarah K
9	Kay GF	Graham F
10	Cox T	Timothy

1 to 10 of 13Source PubMed

See all 13 authors

Topics15

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
DNA (Cytosine-5-)-Methyltransferases	Major topic
Mice	Major topic
Alleles
Animals
Base Sequence
DNA Methylation
Epigenesis, Genetic
Exons
Female
Homozygote
Male
Mice, Transgenic
Molecular Sequence Data
Pedigree
DNA Methyltransferase 3B

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References51

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	10,588,719	The DNMT3B DNA methyltransferase gene is mutated in the ICF immunodeficiency syndrome.	Proc Natl Acad Sci U S A	1999	https://conductscience.org/library/papers/10588719	PubMed
2	22,122,083	Transgenerational genetic effects.	Epigenomics	2010	https://conductscience.org/library/papers/22122083	PubMed
3	11,773,001	Epigenetic analysis of the Dlk1-Gtl2 imprinted domain on mouse chromosome 12: implications for imprinting control from comparison with Igf2-H19.	Hum Mol Genet	2002	https://conductscience.org/library/papers/11773001	PubMed
4	15,302,854	Mouse centric and pericentric satellite repeats form distinct functional heterochromatin.	J Cell Biol	2004	https://conductscience.org/library/papers/15302854	PubMed
5	10,555,141	DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development.	Cell	1999	https://conductscience.org/library/papers/10555141	PubMed
6	11,884,600	Dnmt1 overexpression causes genomic hypermethylation, loss of imprinting, and embryonic lethality.	Mol Cell Biol	2002	https://conductscience.org/library/papers/11884600	PubMed
7	19,099,580	A genome-wide screen for modifiers of transgene variegation identifies genes with critical roles in development.	Genome Biol	2008	https://conductscience.org/library/papers/19099580	PubMed
8	23,173,090	A forward genetic screen identifies eukaryotic translation initiation factor 3, subunit H (eIF3h), as an enhancer of variegation in the mouse.	G3 (Bethesda)	2012	https://conductscience.org/library/papers/23173090	PubMed
9	21,347,845	A missense mutation in the transcription factor Foxo3a causes teratomas and oocyte abnormalities in mice.	Mamm Genome	2011	https://conductscience.org/library/papers/21347845	PubMed
10	21,566,194	Role for piRNAs and noncoding RNA in de novo DNA methylation of the imprinted mouse Rasgrf1 locus.	Science	2011	https://conductscience.org/library/papers/21566194	PubMed

1 to 10 of 51

See all 51 references

Cited by9

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 10 citations.

PMID	Title	Journal	Year	In Papers	Source
42,840,274	Professor Emma Whitelaw, a pioneer of epigenetic inheritance.	Front Epigenet Epigenom	2025	https://conductscience.org/library/papers/42840274	PubMed
38,335,290	CDCA7-associated global aberrant DNA hypomethylation translates to localized, tissue-specific transcriptional responses.	Sci Adv	2024	https://conductscience.org/library/papers/38335290	PubMed
35,351,876	BAF complex-mediated chromatin relaxation is required for establishment of X chromosome inactivation.	Nat Commun	2022	https://conductscience.org/library/papers/35351876	PubMed
33,004,076	Dnmt3b regulates DUX4 expression in a tissue-dependent manner in transgenic D4Z4 mice.	Skelet Muscle	2020	https://conductscience.org/library/papers/33004076	PubMed
27,153,398	Mutations in DNMT3B Modify Epigenetic Repression of the D4Z4 Repeat and the Penetrance of Facioscapulohumeral Dystrophy.	Am J Hum Genet	2016	https://conductscience.org/library/papers/27153398	PubMed
24,781,204	The first mouse mutants of D14Abb1e (Fam208a) show that it is critical for early development.	Mamm Genome	2014	https://conductscience.org/library/papers/24781204	PubMed
24,733,912	Enhanced evolution by stochastically variable modification of epigenetic marks in the early embryo.	Proc Natl Acad Sci U S A	2014	https://conductscience.org/library/papers/24733912	PubMed
24,186,070	The use of mouse models to study epigenetics.	Cold Spring Harb Perspect Biol	2013	https://conductscience.org/library/papers/24186070	PubMed
24,025,402	An ENU mutagenesis screen identifies novel and known genes involved in epigenetic processes in the mouse.	Genome Biol	2013	https://conductscience.org/library/papers/24025402	PubMed

Genes1

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes
DNMT3B	1,789	PubTator's text mining	https://conductscience.org/library/genes/1789

Source NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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