Paper · 24048522
Postnatal soluble FGFR3 therapy rescues achondroplasia symptoms and restores bone growth in mice.
Garcia S and 11 others. Sci Transl Med, 2013. Cited by 75 papers, by iCite.
11 sourcespapers-2026-11-12-0.1.0
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ConductScience Library. Postnatal soluble FGFR3 therapy rescues achondroplasia symptoms and restores bone growth in mice. Papers, record 24048522. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/24048522
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Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
- Title
- Postnatal soluble FGFR3 therapy rescues achondroplasia symptoms and restores bone growth in mice.
- PubMed
Topics9
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Achondroplasia | Major topic |
| Bone Development | Major topic |
| Receptor, Fibroblast Growth Factor, Type 3 | Major topic |
| Animals | |
| Female | |
| Humans | |
| Male | |
| Mice | |
| Signal Transduction |
Source PubMed
Grants0
Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.
None in this release.
Trials0
The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.
None in this release.
Comments and corrections0
PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.
None in this release.
References0
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
None in this release.
Cited by51
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 75 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 42,883,818 | Achondroplasia: Current Disease-Modifying Therapies and Genome Editing Strategies. | Int J Mol Sci | 2026 | https://conductscience.org/library/papers/42883818 | PubMed |
| 40,256,430 | Advances in the mechanism and therapies of achondroplasia. | Genes Dis | 2025 | https://conductscience.org/library/papers/40256430 | PubMed |
| 40,178,985 | TYRA-300, an FGFR3-selective inhibitor, promotes bone growth in two FGFR3-driven models of chondrodysplasia. | JCI Insight | 2025 | https://conductscience.org/library/papers/40178985 | PubMed |
| 39,473,750 | Predictive value of preoperative Fried Frailty Phenotype assessment and serum biomarkers on the prognosis of elderly patients with femoral neck fracture under general anesthesia within 3 months after surgery. | Turk J Med Sci | 2024 | https://conductscience.org/library/papers/39473750 | PubMed |
| 38,544,920 | Long-term oral meclozine administration improves survival rate and spinal canal stenosis during postnatal growth in a mouse model of achondroplasia in both sexes. | JBMR Plus | 2024 | https://conductscience.org/library/papers/38544920 | PubMed |
| 38,455,469 | Tumour cell-expressed PD-L1 reprograms lipid metabolism via EGFR/ITGB4/SREBP1c signalling in liver cancer. | JHEP Rep | 2024 | https://conductscience.org/library/papers/38455469 | PubMed |
| 38,045,829 | Oncofetal reprogramming in tumor development and progression: novel insights into cancer therapy. | MedComm (2020) | 2023 | https://conductscience.org/library/papers/38045829 | PubMed |
| 37,428,729 | Phase 1b study on the repurposing of meclizine hydrochloride for children with achondroplasia. | PLoS One | 2023 | https://conductscience.org/library/papers/37428729 | PubMed |
| 36,765,071 | Intrafusal-fiber LRP4 for muscle spindle formation and maintenance in adult and aged animals. | Nat Commun | 2023 | https://conductscience.org/library/papers/36765071 | PubMed |
| 36,684,552 | Achondroplasia: Clinical, Radiological and Molecular Profile from Rare Disease Centre, India. | J Pediatr Genet | 2023 | https://conductscience.org/library/papers/36684552 | PubMed |
1 to 10 of 51
See all 51 cited byGenes1
The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.
| Gene | NCBI Gene ID | Linked by | In Genes |
|---|---|---|---|
| FGFR3 | 2,261 | PubTator's text mining | https://conductscience.org/library/genes/2261 |
Source NCBI Gene
Drugs0
The drugs whose trials, in the Pipelines release, list the paper.
None in this release.
Data0
The data bank entries PubMed's record names. Trial numbers are under Trials.
None in this release.
Data dates
The date of each source this release read.
- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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