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Paper · 2436062

Quinidine inhibition of the muscarine receptor-activated K+ channel current in atrial cells of guinea pig.

Kurachi Y and 2 others. Naunyn Schmiedebergs Arch Pharmacol, 1987. Cited by 21 papers, by iCite.

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ConductScience Library. Quinidine inhibition of the muscarine receptor-activated K+ channel current in atrial cells of guinea pig. Papers, record 2436062. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/2436062

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Quinidine inhibition of the muscarine receptor-activated K+ channel current in atrial cells of guinea pig.
PubMed
Journal
Naunyn Schmiedebergs Arch Pharmacol
PubMed
Year
1987
PubMed
Publication types
Journal Article, Research Support, Non-U.S. Gov't
PubMed
Citations, by iCite
21
iCite
Relative citation ratio, by iCite
0.53
iCite
Revised in PubMed
2019-07-25
PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Kurachi YY
2Nakajima TT
3Sugimoto TT

Source PubMed

Topics13

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Ion ChannelsMajor topic
MyocardiumMajor topic
QuinidineMajor topic
Receptors, MuscarinicMajor topic
Acetylcholine
Animals
Atropine
Guanosine 5'-O-(3-Thiotriphosphate)
Guanosine Triphosphate
Guinea Pigs
Heart
In Vitro Techniques
Thionucleotides

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References20

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
16,270,629Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches.Pflugers Arch1981https://conductscience.org/library/papers/6270629PubMed
32,418,867Islet activating protein inhibits physiological responses evoked by cardiac muscarinic acetylcholine receptors. Role of guanosine triphosphate binding proteins in regulation of potassium permeability.Biochemistry1985https://conductscience.org/library/papers/2418867PubMed
42,429,251On the mechanism of activation of muscarinic K+ channels by adenosine in isolated atrial cells: involvement of GTP-binding proteins.Pflugers Arch1986https://conductscience.org/library/papers/2429251PubMed
57,177,773Calcium tolerant ventricular myocytes prepared by preincubation in a "KB medium".Pflugers Arch1982https://conductscience.org/library/papers/7177773PubMed
66,704,576Antimuscarinic action of quinidine on the heart? A study in myocardial preparations from cat hearts.Br J Pharmacol1984https://conductscience.org/library/papers/6704576PubMed
72,413,368Uncoupling of cardiac muscarinic and beta-adrenergic receptors from ion channels by a guanine nucleotide analogue.Nature1985https://conductscience.org/library/papers/2413368PubMed
87,192,183Anticholinergic effects of disopyramide and quinidine on guinea pig myocardium. Mediation by direct muscarinic receptor blockade.Circ Res1980https://conductscience.org/library/papers/7192183PubMed
91,177,128Inhibition of the calcium-induced increase in the potassium permeability of human red blood cells by quinine.J Physiol1975https://conductscience.org/library/papers/1177128PubMed
102,431,389Role of intracellular Mg2+ in the activation of muscarinic K+ channel in cardiac atrial cell membrane.Pflugers Arch1986https://conductscience.org/library/papers/2431389PubMed
115,954,128Electrophysiologic effects of quinidine. Studies using chronically implanted electrodes in awake dogs with and without cardiac denervation.Circ Res1966https://conductscience.org/library/papers/5954128PubMed

1 to 10 of 20

See all 20 references

Cited by6

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 21 citations.

PMIDTitleJournalYearIn PapersSource
37,125,314The Brugada syndrome: pharmacological therapy.Eur Heart J Suppl2023https://conductscience.org/library/papers/37125314PubMed
26,696,959Voltage-Sensitive K(+) Channels Inhibit Parasympathetic Ganglion Transmission and Vagal Control of Heart Rate in Hypertensive Rats.Front Neurol2015https://conductscience.org/library/papers/26696959PubMed
2,657,440Anti-cholinergic effect of verapamil on the muscarinic acetylcholine receptor-gated K+ channel in isolated guinea-pig atrial myocytes.Naunyn Schmiedebergs Arch Pharmacol1989https://conductscience.org/library/papers/2657440PubMed
2,446,252Short-term desensitization of muscarinic K+ channel current in isolated atrial myocytes and possible role of GTP-binding proteins.Pflugers Arch1987https://conductscience.org/library/papers/2446252PubMed
2,392,156Anticholinergic action of quinidine sulfate in the rabbit atrioventricular node.Naunyn Schmiedebergs Arch Pharmacol1990https://conductscience.org/library/papers/2392156PubMed
2,159,114Electrophysiologic actions of aprindine in rabbit atrioventricular node.Naunyn Schmiedebergs Arch Pharmacol1990https://conductscience.org/library/papers/2159114PubMed

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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