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Paper25873751

AID to overcome the limitations of genomic information by introducing somatic DNA alterations.

Honjo T and 4 others. Proc Jpn Acad Ser B Phys Biol Sci, 2006. Cited by 0 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. AID to overcome the limitations of genomic information by introducing somatic DNA alterations. Papers, record 25873751. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/25873751

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
AID to overcome the limitations of genomic information by introducing somatic DNA alterations.
PubMed
Journal
Proc Jpn Acad Ser B Phys Biol Sci
PubMed
Year
2006
PubMed
Publication types
Journal Article, Review
PubMed
Citations, by iCite
0
iCite
Relative citation ratio, by iCite
0
iCite
Revised in PubMed
2023-11-10
PubMed

Authors5

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Honjo TTasuku
2Muramatsu MMasamichi
3Nagaoka HHitoshi
4Kinoshita KKazuo
5Shinkura RReiko

Source PubMed

Topics0

NLM's MeSH indexing of the paper, its major topics first.

None in this release.

References215

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
12,111,465Circular DNA is a product of the immunoglobulin class switch rearrangement.Nature1990https://conductscience.org/library/papers/2111465PubMed
29,070,313Retinoic acid induces the expression of germ-line C alpha transcript mainly by a TGF-beta-independent mechanism.Cell Immunol1997https://conductscience.org/library/papers/9070313PubMed
311,376,341DNA polymerase eta is an A-T mutator in somatic hypermutation of immunoglobulin variable genes.Nat Immunol2001https://conductscience.org/library/papers/11376341PubMed
410,077,626Position-dependent inhibition of class-switch recombination by PGK-neor cassettes inserted into the immunoglobulin heavy chain constant region locus.Proc Natl Acad Sci U S A1999https://conductscience.org/library/papers/10077626PubMed
58,475,119Replacement of germ-line epsilon promoter by gene targeting alters control of immunoglobulin heavy chain class switching.Proc Natl Acad Sci U S A1993https://conductscience.org/library/papers/8475119PubMed
68,511,591Molecular cloning of an apolipoprotein B messenger RNA editing protein.Science1993https://conductscience.org/library/papers/8511591PubMed
710,064,064AML and Ets proteins regulate the I alpha1 germ-line promoter.Eur J Immunol1999https://conductscience.org/library/papers/10064064PubMed
814,734,526DNA polymerase eta is involved in hypermutation occurring during immunoglobulin class switch recombination.J Exp Med2004https://conductscience.org/library/papers/14734526PubMed
911,148,220The mu switch region tandem repeats are important, but not required, for antibody class switch recombination.J Exp Med2001https://conductscience.org/library/papers/11148220PubMed
1011,740,565AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching.Nature2001https://conductscience.org/library/papers/11740565PubMed
119,464,828Critical test of hot spot motifs for immunoglobulin hypermutation.Eur J Immunol1997https://conductscience.org/library/papers/9464828PubMed
1211,313,499Structural basis of transcription: an RNA polymerase II elongation complex at 3.3 A resolution.Science2001https://conductscience.org/library/papers/11313499PubMed
1310,475,606Loss of splice consensus signal is responsible for the removal of the entire C(H)1 domain of the functional camel IGG2A heavy-chain antibodies.Mol Immunol1999https://conductscience.org/library/papers/10475606PubMed
1412,910,268AID mutant analyses indicate requirement for class-switch-specific cofactors.Nat Immunol2003https://conductscience.org/library/papers/12910268PubMed
159,710,636The ability of CD40L, but not lipopolysaccharide, to initiate immunoglobulin switching to immunoglobulin G1 is explained by differential induction of NF-kappaB/Rel proteins.Mol Cell Biol1998https://conductscience.org/library/papers/9710636PubMed
169,670,955Somatic hypermutation of an artificial test substrate within an Ig kappa transgene.J Immunol1998https://conductscience.org/library/papers/9670955PubMed
1715,970,938AID to overcome the limitations of genomic information.Nat Immunol2005https://conductscience.org/library/papers/15970938PubMed
182,489,045Molecular requirements for immunoglobulin heavy chain constant region gene switch-recombination revealed with switch-substrate retroviruses.Int Immunol1989https://conductscience.org/library/papers/2489045PubMed
1915,956,553Hepatitis C virus E2-CD81 interaction induces hypermutation of the immunoglobulin gene in B cells.J Virol2005https://conductscience.org/library/papers/15956553PubMed
207,811,382Extrachromosomal eukaryotic DNA substrates for switch recombination: analysis of isotype and cell specificity.DNA Cell Biol1994https://conductscience.org/library/papers/7811382PubMed

See all 215 references

Genes13

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
ACSM36,296PubTator's text mininghttps://conductscience.org/library/genes/6296NCBI Gene
AICDA57,379PubTator's text mininghttps://conductscience.org/library/genes/57379NCBI Gene
APOBEC1339PubTator's text mininghttps://conductscience.org/library/genes/339NCBI Gene
BCL6604PubTator's text mininghttps://conductscience.org/library/genes/604NCBI Gene
CDA978PubTator's text mininghttps://conductscience.org/library/genes/978NCBI Gene
COIL8,161PubTator's text mininghttps://conductscience.org/library/genes/8161NCBI Gene
DNTT1,791PubTator's text mininghttps://conductscience.org/library/genes/1791NCBI Gene
IGH3,492PubTator's text mininghttps://conductscience.org/library/genes/3492NCBI Gene
LOC102723407102,723,407PubTator's text mininghttps://conductscience.org/library/genes/102723407NCBI Gene
MYC4,609PubTator's text mininghttps://conductscience.org/library/genes/4609NCBI Gene
POTEF728,378PubTator's text mininghttps://conductscience.org/library/genes/728378NCBI Gene
SCARA351,435PubTator's text mininghttps://conductscience.org/library/genes/51435NCBI Gene
UBASH3B84,959PubTator's text mininghttps://conductscience.org/library/genes/84959NCBI Gene

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

  • Grants
  • Trials
  • Comments and corrections
  • Cited by
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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