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Paper2822706

Multihormonal regulation of phosphoenolpyruvate carboxykinase-chloramphenicol acetyltransferase fusion genes. Insulin's effects oppose those of cAMP and dexamethasone.

Magnuson MA and 2 others. J Biol Chem, 1987. Cited by 148 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Multihormonal regulation of phosphoenolpyruvate carboxykinase-chloramphenicol acetyltransferase fusion genes. Insulin's effects oppose those of cAMP and dexamethasone. Papers, record 2822706. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/2822706

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Multihormonal regulation of phosphoenolpyruvate carboxykinase-chloramphenicol acetyltransferase fusion genes. Insulin's effects oppose those of cAMP and dexamethasone.
PubMed
Journal
J Biol Chem
PubMed
Year
1987
PubMed
Publication types
Journal Article, Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
148
iCite
Relative citation ratio, by iCite
3.27
iCite
Revised in PubMed
2021-02-10
PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Magnuson MAM A
2Quinn PGP G
3Granner DKD K

Source PubMed

Topics13

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
AcetyltransferasesMajor topic
Cloning, MolecularMajor topic
Cyclic AMPMajor topic
DexamethasoneMajor topic
Gene Expression RegulationMajor topic
GenesMajor topic
InsulinMajor topic
Phosphoenolpyruvate Carboxykinase (GTP)Major topic
Cell Line
Chloramphenicol O-Acetyltransferase
Kinetics
Plasmids
Transfection

Source PubMed

Grants4

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated bySource
AM 20593-09NIADDK NIH HHSUnited StatesPubMedPubMed
AM 35107NIADDK NIH HHSUnited StatesR01AM035107PubMed and NIHNIH RePORTER
T32 AM07061NIADDK NIH HHSUnited StatesT32AM007061PubMed and NIHNIH RePORTER
P60AM020593NIHNIH RePORTER

Cited by36

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 148 citations.

PMIDTitleJournalYearIn PapersSource
27,516,169Targeting hepatic glucose metabolism in the treatment of type 2 diabetes.Nat Rev Drug Discov2016https://conductscience.org/library/papers/27516169PubMed
26,209,640In pursuit of genes of glucose metabolism.J Biol Chem2015https://conductscience.org/library/papers/26209640PubMed
23,328,712Novel views on new-onset diabetes after transplantation: development, prevention and treatment.Nephrol Dial Transplant2013https://conductscience.org/library/papers/23328712PubMed
19,487,561Transcriptional regulation of metabolism associated with the increased desiccation resistance of the cactophilic Drosophila mojavensis.Genetics2009https://conductscience.org/library/papers/19487561PubMed
19,264,844STAT3 targets the regulatory regions of gluconeogenic genes in vivo.Mol Endocrinol2009https://conductscience.org/library/papers/19264844PubMed
10,938,127Phosphoenolpyruvate carboxykinase is necessary for the integration of hepatic energy metabolism.Mol Cell Biol2000https://conductscience.org/library/papers/10938127PubMed
9,658,104Role of the transcription start site core region and transcription factor YY1 in Rous sarcoma virus long terminal repeat promoter activity.J Virol1998https://conductscience.org/library/papers/9658104PubMed
8,264,646MGSA/GRO transcription is differentially regulated in normal retinal pigment epithelial and melanoma cells.Mol Cell Biol1994https://conductscience.org/library/papers/8264646PubMed
8,196,645The insulin gene contains multiple transcriptional elements that respond to glucose.Mol Cell Biol1994https://conductscience.org/library/papers/8196645PubMed
8,100,835Vanadate treatment restores the expression of genes for key enzymes in the glucose and ketone bodies metabolism in the liver of diabetic rats.J Clin Invest1993https://conductscience.org/library/papers/8100835PubMed
8,090,784Transgenic mice overexpressing phosphoenolpyruvate carboxykinase develop non-insulin-dependent diabetes mellitus.Proc Natl Acad Sci U S A1994https://conductscience.org/library/papers/8090784PubMed
8,065,321Simian virus 40 small tumor antigen inhibits dephosphorylation of protein kinase A-phosphorylated CREB and regulates CREB transcriptional stimulation.Mol Cell Biol1994https://conductscience.org/library/papers/8065321PubMed
7,945,228Transcriptional control of genes that regulate glycolysis and gluconeogenesis in adult liver.Biochem J1994https://conductscience.org/library/papers/7945228PubMed
3,422,101Location and characterization of two widely separated glucocorticoid response elements in the phosphoenolpyruvate carboxykinase gene.Mol Cell Biol1988https://conductscience.org/library/papers/3422101PubMed
2,850,495Identification of basal and cyclic AMP regulatory elements in the promoter of the phosphoenolpyruvate carboxykinase gene.Mol Cell Biol1988https://conductscience.org/library/papers/2850495PubMed
2,839,830Insulin stimulates glyceraldehyde-3-phosphate dehydrogenase gene expression through cis-acting DNA sequences.Proc Natl Acad Sci U S A1988https://conductscience.org/library/papers/2839830PubMed
2,834,722Regulation of phosphoenolpyruvate carboxykinase gene transcription by insulin and cAMP: reciprocal actions on initiation and elongation.Proc Natl Acad Sci U S A1988https://conductscience.org/library/papers/2834722PubMed
2,780,291Rat gene 33: analysis of its structure, messenger RNA and basal promoter activity.Nucleic Acids Res1989https://conductscience.org/library/papers/2780291PubMed
2,662,183Rat glucokinase gene: structure and regulation by insulin.Proc Natl Acad Sci U S A1989https://conductscience.org/library/papers/2662183PubMed
2,657,389Hormonal regulation of phosphoenolpyruvate carboxykinase gene expression is mediated through modulation of an already disrupted chromatin structure.Mol Cell Biol1989https://conductscience.org/library/papers/2657389PubMed

See all 36 cited by

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

  • Trials
  • Comments and corrections
  • References
  • Genes
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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