Paper2822706
Multihormonal regulation of phosphoenolpyruvate carboxykinase-chloramphenicol acetyltransferase fusion genes. Insulin's effects oppose those of cAMP and dexamethasone.
Magnuson MA and 2 others. J Biol Chem, 1987. Cited by 148 papers, by iCite.
11 sourcespapers-2026-11-12-0.1.0
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ConductScience Library. Multihormonal regulation of phosphoenolpyruvate carboxykinase-chloramphenicol acetyltransferase fusion genes. Insulin's effects oppose those of cAMP and dexamethasone. Papers, record 2822706. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/2822706
Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
- Title
- Multihormonal regulation of phosphoenolpyruvate carboxykinase-chloramphenicol acetyltransferase fusion genes. Insulin's effects oppose those of cAMP and dexamethasone.
- PubMed
Topics13
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Acetyltransferases | Major topic |
| Cloning, Molecular | Major topic |
| Cyclic AMP | Major topic |
| Dexamethasone | Major topic |
| Gene Expression Regulation | Major topic |
| Genes | Major topic |
| Insulin | Major topic |
| Phosphoenolpyruvate Carboxykinase (GTP) | Major topic |
| Cell Line | |
| Chloramphenicol O-Acetyltransferase | |
| Kinetics | |
| Plasmids | |
| Transfection |
Source PubMed
Grants4
Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.
| Grant, as the record writes it | Agency | Country | NIH project | Stated by | Source |
|---|---|---|---|---|---|
| AM 20593-09 | NIADDK NIH HHS | United States | PubMed | PubMed | |
| AM 35107 | NIADDK NIH HHS | United States | R01AM035107 | PubMed and NIH | NIH RePORTER |
| T32 AM07061 | NIADDK NIH HHS | United States | T32AM007061 | PubMed and NIH | NIH RePORTER |
| P60AM020593 | NIH | NIH RePORTER |
Cited by36
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 148 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 27,516,169 | Targeting hepatic glucose metabolism in the treatment of type 2 diabetes. | Nat Rev Drug Discov | 2016 | https://conductscience.org/library/papers/27516169 | PubMed |
| 26,209,640 | In pursuit of genes of glucose metabolism. | J Biol Chem | 2015 | https://conductscience.org/library/papers/26209640 | PubMed |
| 23,328,712 | Novel views on new-onset diabetes after transplantation: development, prevention and treatment. | Nephrol Dial Transplant | 2013 | https://conductscience.org/library/papers/23328712 | PubMed |
| 19,487,561 | Transcriptional regulation of metabolism associated with the increased desiccation resistance of the cactophilic Drosophila mojavensis. | Genetics | 2009 | https://conductscience.org/library/papers/19487561 | PubMed |
| 19,264,844 | STAT3 targets the regulatory regions of gluconeogenic genes in vivo. | Mol Endocrinol | 2009 | https://conductscience.org/library/papers/19264844 | PubMed |
| 10,938,127 | Phosphoenolpyruvate carboxykinase is necessary for the integration of hepatic energy metabolism. | Mol Cell Biol | 2000 | https://conductscience.org/library/papers/10938127 | PubMed |
| 9,658,104 | Role of the transcription start site core region and transcription factor YY1 in Rous sarcoma virus long terminal repeat promoter activity. | J Virol | 1998 | https://conductscience.org/library/papers/9658104 | PubMed |
| 8,264,646 | MGSA/GRO transcription is differentially regulated in normal retinal pigment epithelial and melanoma cells. | Mol Cell Biol | 1994 | https://conductscience.org/library/papers/8264646 | PubMed |
| 8,196,645 | The insulin gene contains multiple transcriptional elements that respond to glucose. | Mol Cell Biol | 1994 | https://conductscience.org/library/papers/8196645 | PubMed |
| 8,100,835 | Vanadate treatment restores the expression of genes for key enzymes in the glucose and ketone bodies metabolism in the liver of diabetic rats. | J Clin Invest | 1993 | https://conductscience.org/library/papers/8100835 | PubMed |
| 8,090,784 | Transgenic mice overexpressing phosphoenolpyruvate carboxykinase develop non-insulin-dependent diabetes mellitus. | Proc Natl Acad Sci U S A | 1994 | https://conductscience.org/library/papers/8090784 | PubMed |
| 8,065,321 | Simian virus 40 small tumor antigen inhibits dephosphorylation of protein kinase A-phosphorylated CREB and regulates CREB transcriptional stimulation. | Mol Cell Biol | 1994 | https://conductscience.org/library/papers/8065321 | PubMed |
| 7,945,228 | Transcriptional control of genes that regulate glycolysis and gluconeogenesis in adult liver. | Biochem J | 1994 | https://conductscience.org/library/papers/7945228 | PubMed |
| 3,422,101 | Location and characterization of two widely separated glucocorticoid response elements in the phosphoenolpyruvate carboxykinase gene. | Mol Cell Biol | 1988 | https://conductscience.org/library/papers/3422101 | PubMed |
| 2,850,495 | Identification of basal and cyclic AMP regulatory elements in the promoter of the phosphoenolpyruvate carboxykinase gene. | Mol Cell Biol | 1988 | https://conductscience.org/library/papers/2850495 | PubMed |
| 2,839,830 | Insulin stimulates glyceraldehyde-3-phosphate dehydrogenase gene expression through cis-acting DNA sequences. | Proc Natl Acad Sci U S A | 1988 | https://conductscience.org/library/papers/2839830 | PubMed |
| 2,834,722 | Regulation of phosphoenolpyruvate carboxykinase gene transcription by insulin and cAMP: reciprocal actions on initiation and elongation. | Proc Natl Acad Sci U S A | 1988 | https://conductscience.org/library/papers/2834722 | PubMed |
| 2,780,291 | Rat gene 33: analysis of its structure, messenger RNA and basal promoter activity. | Nucleic Acids Res | 1989 | https://conductscience.org/library/papers/2780291 | PubMed |
| 2,662,183 | Rat glucokinase gene: structure and regulation by insulin. | Proc Natl Acad Sci U S A | 1989 | https://conductscience.org/library/papers/2662183 | PubMed |
| 2,657,389 | Hormonal regulation of phosphoenolpyruvate carboxykinase gene expression is mediated through modulation of an already disrupted chromatin structure. | Mol Cell Biol | 1989 | https://conductscience.org/library/papers/2657389 | PubMed |
Data dates
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- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
None in this release
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- Comments and corrections
- References
- Genes
- Drugs
- Data
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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