Paper · 3022285

Type beta transforming growth factor is an inhibitor of myogenic differentiation.

Massagué J and 3 others. Proc Natl Acad Sci U S A, 1986. Cited by 566 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Type beta transforming growth factor is an inhibitor of myogenic differentiation. Papers, record 3022285. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/3022285

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Type beta transforming growth factor is an inhibitor of myogenic differentiation.; PubMed
Journal: Proc Natl Acad Sci U S A; PubMed
Year: 1986; PubMed
Publication types: Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/3022285/; PubMed
DOI: https://doi.org/10.1073/pnas.83.21.8206; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC386896/; PubMed
The journal: https://conductscience.org/library/journal-index/7505876; PubMed
Citations, by iCite: 566; iCite
Relative citation ratio, by iCite: 12.3; iCite
Revised in PubMed: 2019-05-01; PubMed

Authors4

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Massagué J	J
2	Cheifetz S	S
3	Endo T	T
4	Nadal-Ginard B	B

Source PubMed

Topics11

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Muscles	Major topic
Peptides	Major topic
Cell Differentiation
Cell Fusion
Cell Line
Collagen
Creatine Kinase
Fibronectins
RNA, Messenger
Receptors, Cell Surface
Transforming Growth Factors

Source PubMed

Grants3

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes it	Agency	Country	NIH project	Stated by	Source
CA34610	NCI NIH HHS	United States	R01CA034610	PubMed and NIH	NIH RePORTER
GM33577	NIGMS NIH HHS	United States	R01GM033577	PubMed and NIH	NIH RePORTER
			R37CA034610	NIH	NIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References31

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	5,245,982	Retention of differentiation potentialities during prolonged cultivation of myogenic cells.	Proc Natl Acad Sci U S A	1968	https://conductscience.org/library/papers/5245982	PubMed
3	236,308	High resolution two-dimensional electrophoresis of proteins.	J Biol Chem	1975	https://conductscience.org/library/papers/236308	PubMed
4	945,805	Effect of fibroblast growth factor on the division and fusion of bovine myoblasts.	J Cell Biol	1976	https://conductscience.org/library/papers/945805	PubMed
5	728,992	Commitment, fusion and biochemical differentiation of a myogenic cell line in the absence of DNA synthesis.	Cell	1978	https://conductscience.org/library/papers/728992	PubMed
6	510,407	Fibronectin delays the fusion of L6 myoblasts.	Exp Cell Res	1979	https://conductscience.org/library/papers/510407	PubMed
7	527,766	Changes in protein synthesis during myogenesis in a clonal cell line.	Dev Biol	1979	https://conductscience.org/library/papers/527766	PubMed
8	7,431,393	Transient induction of poly(A)-short myosin heavy chain messenger RNA during terminal differentiation of L6E9 myoblasts.	J Mol Biol	1980	https://conductscience.org/library/papers/7431393	PubMed
9	6,265,069	Transforming growth factor production by chemically transformed cells.	Cancer Res	1981	https://conductscience.org/library/papers/6265069	PubMed
10	7,286,410	The correlation between the synthesis of skeletal muscle actin, myosin heavy chain, and myosin light chain and the accumulation of corresponding mRNA sequences during myogenesis.	Dev Biol	1981	https://conductscience.org/library/papers/7286410	PubMed
11	6,975,480	New class of transforming growth factors potentiated by epidermal growth factor: isolation from non-neoplastic tissues.	Proc Natl Acad Sci U S A	1981	https://conductscience.org/library/papers/6975480	PubMed

1 to 10 of 31

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Cited by191

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 566 citations.

PMID	Title	Journal	Year	In Papers	Source
42,278,293	Regenerative Medicine: Advanced Therapy for Muscle Tissue Restoration.	Int J Mol Sci	2026	https://conductscience.org/library/papers/42278293	PubMed
41,783,860	Chicken Embryo Extract Remodeling of Extracellular Matrix Sustains Self-Renewal and Differentiation for Scaffold-Free Cell Sheet Formation.	Biomater Res	2026	https://conductscience.org/library/papers/41783860	PubMed
41,725,369	Senescent-Like Myofibers Contribute to Anti-Regenerative Cytokine Signaling in Duchenne Muscular Dystrophy.	FASEB J	2026	https://conductscience.org/library/papers/41725369	PubMed
41,286,086	Regulatory role of vitamin D3 on myogenesis and fibrogenesis under Vdr gene silencing and TGF-β1 stimulation in skeletal muscle cells.	Sci Rep	2025	https://conductscience.org/library/papers/41286086	PubMed
40,535,569	Differential regulation of MMP activity by TGFβ1 in fast- and slow- twitch muscle repair: insights from EDL and soleus muscle-derived myoblasts.	Front Cell Dev Biol	2025	https://conductscience.org/library/papers/40535569	PubMed
40,507,960	Quercetin, Kaempferol and Capsaicin Counteract the TGF-β1-Induced Upregulation of αSMA and Collagen in Myoblasts.	Int J Mol Sci	2025	https://conductscience.org/library/papers/40507960	PubMed
40,212,253	A Glance into the Near Future: Cultivated Meat from Mammalian and Insect Cells.	Small Sci	2024	https://conductscience.org/library/papers/40212253	PubMed
40,178,931	The role of inner nuclear membrane protein emerin in myogenesis.	FASEB J	2025	https://conductscience.org/library/papers/40178931	PubMed
39,999,085	Identification of suitable qPCR reference genes for the normalization of gene expression in the BL10-mdx and D2-mdx mouse models of Duchenne muscular dystrophy.	PLoS One	2025	https://conductscience.org/library/papers/39999085	PubMed
39,380,256	TGF-β effects on adipogenesis of 3T3-L1 cells differ in 2D and 3D cell culture conditions.	FEBS Open Bio	2024	https://conductscience.org/library/papers/39380256	PubMed

1 to 10 of 191

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Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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