Paper308952

Suppressor-cell dysfunction in systemic lupus erythematosus. Cells involved and in vitro correction.

Sagawa A and 1 other. J Clin Invest, 1978. Cited by 186 papers, by iCite.

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ConductScience Library. Suppressor-cell dysfunction in systemic lupus erythematosus. Cells involved and in vitro correction. Papers, record 308952. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/308952

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Suppressor-cell dysfunction in systemic lupus erythematosus. Cells involved and in vitro correction.; PubMed
Journal: J Clin Invest; PubMed
Year: 1978; PubMed
Publication types: Journal Article, Research Support, U.S. Gov't, Non-P.H.S.; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/308952/; PubMed
DOI: https://doi.org/10.1172/jci109190; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC371830/; PubMed
The journal: https://conductscience.org/library/journal-index/7802877; PubMed
Citations, by iCite: 186; iCite
Relative citation ratio, by iCite: 6.13; iCite
Revised in PubMed: 2021-12-03; PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	Kind	ORCID iD
1	Sagawa A	A
2	Abdou NI	N I

Source PubMed

Topics8

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Immunosuppression Therapy	Major topic
Lupus Erythematosus, Systemic	Major topic
Monocytes	Major topic
T-Lymphocytes	Major topic
Concanavalin A
Humans
Immunity, Cellular
Lymphocyte Activation

Source PubMed

Show 2 more topicsShow fewer topics

References27

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	71,963	Role of suppressor T cells in lymphopoietic disorders.	Clin Haematol	1977	https://conductscience.org/library/papers/71963	PubMed
2	70,319	Suppressor T cells in tolerance to non-self and self antigens.	Cold Spring Harb Symp Quant Biol	1977	https://conductscience.org/library/papers/70319	PubMed
3	68,777	Monocyte-reactive antibodies in patients with systemic lupus erythematosus.	Arthritis Rheum	1977	https://conductscience.org/library/papers/68777	PubMed
4	325,412	Concomitant presence of tumor-specific cytotoxic and inhibitor lymphocytes in patients with osteogenic sarcoma.	N Engl J Med	1977	https://conductscience.org/library/papers/325412	PubMed
5	305,925	Suppressor cell-mediated neutropenia in Felty's syndrome.	J Clin Invest	1978	https://conductscience.org/library/papers/305925	PubMed
6	302,032	Induction of suppressor T cells in systemic lupus erythematosus by thymosin and cultured thymic epithelium.	Science	1977	https://conductscience.org/library/papers/302032	PubMed
7	300,174	Prevention of autoimmunity in experimental lupus erythematosus by soluble immune response suppressor.	Science	1977	https://conductscience.org/library/papers/300174	PubMed
8	830,659	Suppressor function of peripheral blood mononuclear cells in normal individuals and in patients with systemic lupus erythematosus.	J Clin Invest	1977	https://conductscience.org/library/papers/830659	PubMed
9	1,085,685	Suppressor T-cell abnormality in idiopathic systemic lupus erythematosus.	Clin Immunol Immunopathol	1976	https://conductscience.org/library/papers/1085685	PubMed
10	1,086,175	Null cells in peripheral blood of normals and systemic lupus erythematosus.	Clin Immunol Immunopathol	1976	https://conductscience.org/library/papers/1086175	PubMed
11	4,137,918	Role of suppressor T cells in pathogenesis of common variable hypogammaglobulinaemia.	Lancet	1974	https://conductscience.org/library/papers/4137918	PubMed
12	4,133,998	The roles of T and B lymphocytes in self-tolerance and autoimmunity.	Contemp Top Immunobiol	1974	https://conductscience.org/library/papers/4133998	PubMed
13	55,418	Fractionation of cells on a discontinuous Ficoll gradient. Study of subpopulations of human T cells using anti-T-cell antibodies from patients with systemic lupus erythematosus.	J Clin Invest	1976	https://conductscience.org/library/papers/55418	PubMed
14	4,575,171	Relative T-cell specificity of lymphocytotoxins from patients with systemic lupus erythematosus.	Arthritis Rheum	1973	https://conductscience.org/library/papers/4575171	PubMed
15	4,592,599	Biological expressions of lymphocyte activation. 3. Suppression of plaque-forming cell responses in vitro by supernatant fluids from concanavalin A-activated spleen cell cultures.	J Immunol	1974	https://conductscience.org/library/papers/4592599	PubMed
16	4,570,017	Biological expressions of lymphocyte activation. II. Generation of a population of thymus-derived suppressor lymphocytes.	J Exp Med	1973	https://conductscience.org/library/papers/4570017	PubMed
17	4,541,466	A Millipore filter assay for antibodies to native DNA in sera of patients with systemic lupus erythematosus.	Arthritis Rheum	1973	https://conductscience.org/library/papers/4541466	PubMed
18	166,312	Viruses and systemic lupus erythematosus.	N Engl J Med	1975	https://conductscience.org/library/papers/166312	PubMed
19	131,175	Suppressor cell activity after concanavalin A treatment of lymphocytes from normal donors.	J Exp Med	1976	https://conductscience.org/library/papers/131175	PubMed
20	4,641,854	Inhibitory and stimulatory effects of concanavalin A on the response of mouse spleen cell suspensions to antigen. I. Characterization of the inhibitory cell activity.	J Exp Med	1972	https://conductscience.org/library/papers/4641854	PubMed

Show 14 more referencesShow fewer referencesSee all 27 references

Cited by44

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 186 citations.

PMID	Title	Journal	Year	In Papers	Source
35,925,475	The emerging role of T cells in pemphigus vulgaris: a systematic review.	Clin Exp Med	2023	https://conductscience.org/library/papers/35925475	PubMed
7,307,347	Generation of a soluble immune response suppressor factor (IRSF) by unstimulated leukocytes of healthy subjects.	Clin Exp Immunol	1981	https://conductscience.org/library/papers/7307347	PubMed
7,200,840	Hydrocortisone reverses the suppression of immunoglobulin synthesis by concanavalin A-activated spleen cell supernatants.	Clin Exp Immunol	1982	https://conductscience.org/library/papers/7200840	PubMed
7,051,837	Autoimmune diseases: immunopathology and etiopathogenesis.	Am J Pathol	1982	https://conductscience.org/library/papers/7051837	PubMed
7,000,827	Alterations in immunoregulatory T cell subsets in active systemic lupus erythematosus.	J Clin Invest	1980	https://conductscience.org/library/papers/7000827	PubMed
6,978,891	T lymphocyte interaction with immunoglobulin G antibody in systemic lupus erythematosus.	J Clin Invest	1982	https://conductscience.org/library/papers/6978891	PubMed
6,975,086	Lymphocyte studies in pemphigus.	Arch Dermatol Res	1981	https://conductscience.org/library/papers/6975086	PubMed
6,971,876	Network theory in autoimmunity. In vitro suppression of serum anti-DNA antibody binding to DNA by anti-idiotypic antibody in systemic lupus erythematosus.	J Clin Invest	1981	https://conductscience.org/library/papers/6971876	PubMed
6,970,750	Antibodies to T cells in patients with systemic lupus erythematosus can induce antibody-dependent cell-mediated cytotoxicity against human T cells.	J Clin Invest	1981	https://conductscience.org/library/papers/6970750	PubMed
6,947,981	Anti-Ia reactivity in sera from patients with systemic lupus erythematosus.	J Clin Invest	1982	https://conductscience.org/library/papers/6947981	PubMed
6,751,633	Spontaneous plaque forming cells in the peripheral blood of patients with systemic lupus erythematosus.	Clin Exp Immunol	1982	https://conductscience.org/library/papers/6751633	PubMed
6,629,415	Suppression of in-vitro antibody production by pokeweed mitogen-stimulated human bone-marrow mononuclear cells. Evidence for a soluble suppressor substance.	Immunology	1983	https://conductscience.org/library/papers/6629415	PubMed
6,609,932	Lymphocyte-reactive antibodies in acquired immune deficiency syndrome.	J Clin Immunol	1984	https://conductscience.org/library/papers/6609932	PubMed
6,460,783	Immunoregulatory T-cell dysfunction in polyclonal gammopathy.	J Clin Immunol	1981	https://conductscience.org/library/papers/6460783	PubMed
6,452,237	Relationship between T cell subpopulations and the mitogen responsiveness and suppressor cell function of peripheral blood mononuclear cells in normal individuals.	Clin Exp Immunol	1980	https://conductscience.org/library/papers/6452237	PubMed
6,451,634	Autoantibody to an immunoregulatory inducer population in patients with juvenile rheumatoid arthritis.	J Clin Invest	1981	https://conductscience.org/library/papers/6451634	PubMed
6,451,338	Immune regulation in inflammatory bowel disease: absence of a serum inhibitor of suppressor cell function.	Clin Exp Immunol	1980	https://conductscience.org/library/papers/6451338	PubMed
6,446,432	Suppressor cell defect in SLE: relationship to native DNA binding.	Clin Exp Immunol	1980	https://conductscience.org/library/papers/6446432	PubMed
6,444,308	Immunoregulation in Sjögren's syndrome: influence of serum factors on T-cell subpopulations.	J Clin Invest	1980	https://conductscience.org/library/papers/6444308	PubMed
6,355,184	Impaired T cell capping and receptor regeneration in active systemic lupus erythematosus. Evidence for a disorder intrinsic to the T lymphocyte.	J Clin Invest	1983	https://conductscience.org/library/papers/6355184	PubMed

Show 14 more cited byShow fewer cited bySee all 44 cited by

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PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

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