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Paper · 31574461

Insight into the mechanism of ferroptosis inhibition by ferrostatin-1.

Miotto G and 13 others. Redox Biol, 2020. Cited by 790 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Insight into the mechanism of ferroptosis inhibition by ferrostatin-1. Papers, record 31574461. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/31574461

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Insight into the mechanism of ferroptosis inhibition by ferrostatin-1.
PubMed
Journal
Redox Biol
PubMed
Year
2020
PubMed
Publication types
Journal Article, Research Support, Non-U.S. Gov't
PubMed
Citations, by iCite
790
iCite
Relative citation ratio, by iCite
41.9
iCite
Revised in PubMed
2023-10-14
PubMed

Authors14

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Miotto GGiovanni
2Rossetto MMonica
3Di Paolo MLMaria Luisa
4Orian LLaura
5Venerando RRina
6Roveri AAntonella
7Vučković AMAna-Marija
8Bosello Travain VValentina
9Zaccarin MMattia
10Zennaro LLucio

1 to 10 of 14Source PubMed

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Topics17

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
CyclohexylaminesMajor topic
FerroptosisMajor topic
PhenylenediaminesMajor topic
Antioxidants
Cell Death
Chromatography, Liquid
Density Functional Theory
Dose-Response Relationship, Drug
Hydrogen
Lipid Peroxidation
Lipid Peroxides
Lipidomics
Lipids
Models, Molecular
Molecular Structure
Oxidation-Reduction
Tandem Mass Spectrometry

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References36

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
126,775,689Regulated necrosis: disease relevance and therapeutic opportunities.Nat Rev Drug Discov2016https://conductscience.org/library/papers/26775689PubMed
24,018,255Quantitative measurement of the total, peroxyl radical-trapping antioxidant capability of human blood plasma by controlled peroxidation. The important contribution made by plasma proteins.FEBS Lett1985https://conductscience.org/library/papers/4018255PubMed
328,734,877Enzymatic and free radical formation of cis- and trans- epoxyeicosatrienoic acids in vitro and in vivo.Free Radic Biol Med2017https://conductscience.org/library/papers/28734877PubMed
47,524,677Purification and characterization of phospholipid hydroperoxide glutathione peroxidase from rat testis mitochondrial membranes.Biochim Biophys Acta1994https://conductscience.org/library/papers/7524677PubMed
525,402,683Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice.Nat Cell Biol2014https://conductscience.org/library/papers/25402683PubMed
68,617,728The selenoenzyme phospholipid hydroperoxide glutathione peroxidase controls the activity of the 15-lipoxygenase with complex substrates and preserves the specificity of the oxygenation products.J Biol Chem1996https://conductscience.org/library/papers/8617728PubMed
729,749,412O-Phenylenediamine: a privileged pharmacophore of ferrostatins for radical-trapping reactivity in blocking ferroptosis.Org Biomol Chem2018https://conductscience.org/library/papers/29749412PubMed
817,326,688What is responsible for the initiating chemistry of iron-mediated lipid peroxidation: an update.Chem Rev2007https://conductscience.org/library/papers/17326688PubMed
928,471,643Lipostar, a Comprehensive Platform-Neutral Cheminformatics Tool for Lipidomics.Anal Chem2017https://conductscience.org/library/papers/28471643PubMed
107,066,358Purification from pig liver of a protein which protects liposomes and biomembranes from peroxidative degradation and exhibits glutathione peroxidase activity on phosphatidylcholine hydroperoxides.Biochim Biophys Acta1982https://conductscience.org/library/papers/7066358PubMed

1 to 10 of 36

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Cited by460

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 790 citations.

PMIDTitleJournalYearIn PapersSource
42,972,140Fumarate hydratase deficiency triggers disulfidptosis under glucose deprivation.Nat Commun2026https://conductscience.org/library/papers/42972140PubMed
42,949,000Discovering ferroptosis in biliary epithelium during liver fibrosis.Eur J Histochem2026https://conductscience.org/library/papers/42949000PubMed
42,939,457Infectious Bronchitis Virus Infection Induces Ferroptosis-Associated Changes with Lipid Peroxidation Dysregulation and Modulates Viral Replication.Biology (Basel)2026https://conductscience.org/library/papers/42939457PubMed
42,935,726Comparative transcriptomic analysis reveals the protective mechanism of ferulic acid against lipopolysaccharide-induced ferroptosis in IPEC-J2 cells.Front Vet Sci2026https://conductscience.org/library/papers/42935726PubMed
42,934,350Microglial NUS1 deficiency drives dopaminergic neurodegeneration through intercellular iron dysregulation in Parkinson's disease models.Nat Neurosci2026https://conductscience.org/library/papers/42934350PubMed
42,884,099Placental Iron Homeostasis: Navigating the Delicate Balance Between Transport and Ferroptosis.Int J Mol Sci2026https://conductscience.org/library/papers/42884099PubMed
42,855,459C2ORF68 stabilizes SIVA1 to upregulate BCL-2 and suppress apoptosis in gallbladder cancer.Cell Death Discov2026https://conductscience.org/library/papers/42855459PubMed
42,793,250Ferrostatin-1 Attenuates CLP-Induced Colonic Injury: Associations with Ferroptosis-Related Alterations, Oxidative Stress, Inflammation, and Treatment Timing.Curr Issues Mol Biol2026https://conductscience.org/library/papers/42793250PubMed
42,781,099Disulfidptosis in heart failure: an emerging mechanism awaiting exploration.Front Cardiovasc Med2026https://conductscience.org/library/papers/42781099PubMed
42,762,285Exposure to Polystyrene Nanoplastics Induces Ferroptosis-Associated Cardiac Injury: Cell-Based Evidence for Lysosome-Associated NLRX1 Loss and an NLRX1-STING-NCOA4 Response.Cardiovasc Toxicol2026https://conductscience.org/library/papers/42762285PubMed

1 to 10 of 460

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Genes2

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
ALOX15246PubTator's text mininghttps://conductscience.org/library/genes/246NCBI Gene
GPX42,879PubTator's text mininghttps://conductscience.org/library/genes/2879NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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