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Paper · 330353

Double-blind clinical trial on gastroduodenal ulcer healing with prostaglandin E2 analogues.

Gibiński K and 3 others. Gut, 1977. Cited by 118 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Double-blind clinical trial on gastroduodenal ulcer healing with prostaglandin E2 analogues. Papers, record 330353. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/330353

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Double-blind clinical trial on gastroduodenal ulcer healing with prostaglandin E2 analogues.
PubMed
Journal
Gut
PubMed
Year
1977
PubMed
Publication types
Clinical Trial, Controlled Clinical Trial, Journal Article, Randomized Controlled Trial
PubMed
Citations, by iCite
118
iCite
Relative citation ratio, by iCite
7.22
iCite
Revised in PubMed
2019-05-01
PubMed

Authors4

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Gibiński KK
2Rybicka JJ
3Mikoś EE
4Nowak AA

Source PubMed

Topics11

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Peptic UlcerMajor topic
Prostaglandins EMajor topic
Adult
Aged
Clinical Trials as Topic
Double-Blind Method
Gastric Juice
Humans
Male
Middle Aged
Prostaglandins, Synthetic

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References13

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
14,134,406Effect of 15(R)15 methylprostaglandin E2 methyl ester on healing of gastric ulcers. Controlled endoscopic study.Lancet1974https://conductscience.org/library/papers/4134406PubMed
24,432,047Gastric secretory inhibition by certain methyl analogs of prostaglandin E2 following intestinal administration in man.Scand J Gastroenterol1974https://conductscience.org/library/papers/4432047PubMed
34,432,046Gastric secretory inhibition induced by three methyl analogs of prostaglandin E2 administered intragastrically to man.Scand J Gastroenterol1974https://conductscience.org/library/papers/4432046PubMed
44,848,482[Diagnostic value of fiberoduodenoscopy].Przegl Lek1974https://conductscience.org/library/papers/4848482PubMed
54,823,988Marked inhibition of gastric secretion by two prostaglandin analogs given orally to man.Life Sci1974https://conductscience.org/library/papers/4823988PubMed
64,728,438The effect of orally and intravenously administered prostaglandin 16:16 dimethyl E2 methyl ester on human gastric acid secretion.Prostaglandins1973https://conductscience.org/library/papers/4728438PubMed
74,706,806Effect of orally administered prostaglandin E 2 and its 15-methyl analogues on gastric secretion.Br Med J1973https://conductscience.org/library/papers/4706806PubMed
81,099,898Antacid vs placebo in hospitalized gastric ulcer patients: a controlled therapeutic study.Am J Dig Dis1975https://conductscience.org/library/papers/1099898PubMed
9770,226Comparison of methylated prostaglandin E2 analogues given orally in the inhibition of gastric responses to pentagastrin and peptone meal in man.Gastroenterology1976https://conductscience.org/library/papers/770226PubMed
101,254,135The effect of 16,16-dimethyl prostaglandin E2 on meal-stimulated gastric acid secretion and serum gastrin in duodenal ulcer patients.Gastroenterology1976https://conductscience.org/library/papers/1254135PubMed

1 to 10 of 13

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Cited by20

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 118 citations.

PMIDTitleJournalYearIn PapersSource
28,479,736In-vitro Wound Healing Effect of 15-Hydroxyprostaglandin Dehydrogenase Inhibitor from Plant.Pharmacogn Mag2017https://conductscience.org/library/papers/28479736PubMed
7,059,450Effect of oral 16,16-dimethyl-prostaglandin E2 on basal acid output in man.Br J Clin Pharmacol1982https://conductscience.org/library/papers/7059450PubMed
6,185,289Oral tripotassium-dicitratobismuthate in gastric and duodenal ulceration. A double-blind controlled trial.Dig Dis Sci1983https://conductscience.org/library/papers/6185289PubMed
6,133,734Newer antisecretory agents for peptic ulcer.Drugs1983https://conductscience.org/library/papers/6133734PubMed
6,107,146New drugs for peptic ulcer.Br Med J1980https://conductscience.org/library/papers/6107146PubMed
4,068,610[Histological and ultrastructural findings in the healing phase of duodenal ulcer].Klin Wochenschr1985https://conductscience.org/library/papers/4068610PubMed
3,943,457Therapeutic aspects of prostaglandins in the treatment of peptic ulcer disease.Dig Dis Sci1986https://conductscience.org/library/papers/3943457PubMed
3,932,052Interim results of a multicenter international comparison of misoprostol and cimetidine in the treatment of out-patients with benign gastric ulcers.Dig Dis Sci1985https://conductscience.org/library/papers/3932052PubMed
3,932,051A multicenter international controlled comparison of two dosage regimes of misoprostol and cimetidine in the treatment of duodenal ulcer in out-patients.Dig Dis Sci1985https://conductscience.org/library/papers/3932051PubMed
3,863,751Prostaglandins in pathophysiology of peptic ulcer disease.Dig Dis Sci1985https://conductscience.org/library/papers/3863751PubMed

1 to 10 of 20

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Genes1

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn Genes
GAST2,520PubTator's text mininghttps://conductscience.org/library/genes/2520

Source NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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