Paper · 770226

Comparison of methylated prostaglandin E2 analogues given orally in the inhibition of gastric responses to pentagastrin and peptone meal in man.

Konturek SJ and 5 others. Gastroenterology, 1976. Cited by 78 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Comparison of methylated prostaglandin E2 analogues given orally in the inhibition of gastric responses to pentagastrin and peptone meal in man. Papers, record 770226. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/770226

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Comparison of methylated prostaglandin E2 analogues given orally in the inhibition of gastric responses to pentagastrin and peptone meal in man.; PubMed
Journal: Gastroenterology; PubMed
Year: 1976; PubMed
Publication types: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/770226/; PubMed
The journal: https://conductscience.org/library/journal-index/0374630; PubMed
Citations, by iCite: 78; iCite
Relative citation ratio, by iCite: 3.82; iCite
Revised in PubMed: 2018-12-03; PubMed

Authors6

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename
1	Konturek SJ	S J
2	Kwiecień N	N
3	Swierczek J	J
4	Oleksy J	J
5	Sito E	E
6	Robert A	A

Source PubMed

Topics13

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Pentagastrin	Major topic
Peptones	Major topic
Prostaglandins E	Major topic
Stomach	Major topic
Administration, Oral
Adult
Depression, Chemical
Gastric Juice
Gastrins
Humans
Male
Methylation
Pepsin A

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

None in this release.

Cited by20

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 78 citations.

PMID	Title	Journal	Year	In Papers	Source
6,585,285	Oral antisecretory activity of prostaglandin E2 in man.	Dig Dis Sci	1984	https://conductscience.org/library/papers/6585285	PubMed
4,043,145	Absorption, tissue distribution, and excretion of 3H-labeled arbaprostil in the male rat.	Eur J Drug Metab Pharmacokinet	1985	https://conductscience.org/library/papers/4043145	PubMed
3,954,940	Arbaprostil (15(R)-15-methyl PGE2): lack of effect on theophylline metabolism.	Br J Clin Pharmacol	1986	https://conductscience.org/library/papers/3954940	PubMed
3,924,533	Reduction of aspirin-induced fecal blood loss with low-dose misoprostol tablets in man.	Dig Dis Sci	1985	https://conductscience.org/library/papers/3924533	PubMed
3,924,152	Prostaglandin formation by isolated gastric parietal and nonparietal cells of the rat.	Br J Pharmacol	1985	https://conductscience.org/library/papers/3924152	PubMed
3,792,228	Prostaglandins in peptic ulcer disease. An overview of current status and future directions.	Drugs	1986	https://conductscience.org/library/papers/3792228	PubMed
3,720,796	Isolation and characterization of urinary metabolites of arbaprostil in the rat.	Eur J Drug Metab Pharmacokinet	1986	https://conductscience.org/library/papers/3720796	PubMed
3,208,790	Isolation and characterization of the urinary metabolites of arbaprostil in the male dog after intravenous administration.	Eur J Drug Metab Pharmacokinet	1988	https://conductscience.org/library/papers/3208790	PubMed
3,117,511	Antisecretory and antigastrin effects of rioprostil in gastric fistula dogs.	Dig Dis Sci	1987	https://conductscience.org/library/papers/3117511	PubMed
3,080,290	Physiology and pharmacology of prostaglandins.	Dig Dis Sci	1986	https://conductscience.org/library/papers/3080290	PubMed

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Genes2

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes	Source
GAST	2,520	PubTator's text mining	https://conductscience.org/library/genes/2520	NCBI Gene
PGA5	5,222	PubTator's text mining	https://conductscience.org/library/genes/5222	NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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