ConductScience.org, home
Papers
API referenceFor AI assistants

Paper · 345245

Insertion of synthetic copies of human globin genes into bacterial plasmids.

Wilson JT and 6 others. Nucleic Acids Res, 1978. Cited by 363 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

Download JSON
Cite this record

ConductScience Library. Insertion of synthetic copies of human globin genes into bacterial plasmids. Papers, record 345245. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/345245

On this page

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Insertion of synthetic copies of human globin genes into bacterial plasmids.
PubMed
Journal
Nucleic Acids Res
PubMed
Year
1978
PubMed
Publication types
Journal Article, Research Support, U.S. Gov't, P.H.S.
PubMed
Citations, by iCite
363
iCite
Relative citation ratio, by iCite
7.51
iCite
Revised in PubMed
2019-05-01
PubMed

Authors7

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Wilson JTJ T
2Wilson LBL B
3deRiel JKJ K
4Villa-komaroff LL
5Efstratiadis AA
6Forget BGB G
7Weissman SMS M

Source PubMed

Topics12

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
DNA, RecombinantMajor topic
GenesMajor topic
GlobinsMajor topic
Base Sequence
Codon
DNA Restriction Enzymes
Escherichia coli
Genetic Engineering
Humans
Nucleic Acid Hybridization
Plasmids
Transformation, Genetic

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References22

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
1803,101Absence of functional messenger RNA activity for beta globin chain synthesis in beta 0-thalassemia.Blood1975https://conductscience.org/library/papers/803101PubMed
2270,752The nucleotide sequences of the untranslated 5' regions of human alpha- and beta-globin mRNAs.Proc Natl Acad Sci U S A1977https://conductscience.org/library/papers/270752PubMed
3909,779Nucleotide sequence of 3' untranslated portion of human alpha globin mRNA.Nucleic Acids Res1977https://conductscience.org/library/papers/909779PubMed
468,958Human beta-globin messenger RNA. III. Nucleotide sequences derived from complementary DNA.J Biol Chem1977https://conductscience.org/library/papers/68958PubMed
5318,159Human beta-globin messenger RNA. II. nucleotide sequences derived from 125I-labeled globin messenger RNA.J Biol Chem1977https://conductscience.org/library/papers/318159PubMed
6847,468Human globin messenger RNA: importance of cloning for structural analysis.Science1977https://conductscience.org/library/papers/847468PubMed
761,588A general method for cloning eukaryotic structural gene sequences.Proc Natl Acad Sci U S A1976https://conductscience.org/library/papers/61588PubMed
81,035,137The 3' terminal sequences of human alpha and beta globin messenger RNAs: comparison with rabbit globin messenger RNA.Cell1976https://conductscience.org/library/papers/1035137PubMed
91,033,038Dictyostelium 17S, 25S, and 5S rDNAs lie within a 38,000 base pair repeated unit.Cell1976https://conductscience.org/library/papers/1033038PubMed
1061,066Amplification and characterization of a beta-globin gene synthesized in vitro.Cell1976https://conductscience.org/library/papers/61066PubMed

1 to 10 of 22

See all 22 references

Cited by110

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 363 citations.

PMIDTitleJournalYearIn PapersSource
42,254,811The Molecular Pathology of Non-Malignant Haematological Disease.Br J Biomed Sci2026https://conductscience.org/library/papers/42254811PubMed
36,482,771RNA in Therapeutics: CRISPR in the Clinic.Mol Cells2023https://conductscience.org/library/papers/36482771PubMed
30,226,837Large-scale investigation of the reasons why potentially important genes are ignored.PLoS Biol2018https://conductscience.org/library/papers/30226837PubMed
9,556,666Extremely high frequencies of alpha-globin gene deletion in Madang and on Kar Kar Island, Papua New Guinea.Am J Hum Genet1985https://conductscience.org/library/papers/9556666PubMed
8,384,722Reactive oxygen intermediates target CC(A/T)6GG sequences to mediate activation of the early growth response 1 transcription factor gene by ionizing radiation.Proc Natl Acad Sci U S A1993https://conductscience.org/library/papers/8384722PubMed
7,440,717Two different molecular organizations account for the single alpha-globin gene of the alpha-thalassemia-2 genotype.J Clin Invest1980https://conductscience.org/library/papers/7440717PubMed
7,433,096Mapping sequences in loops of nuclear DNA by their progressive detachment from the nuclear cage.Nucleic Acids Res1980https://conductscience.org/library/papers/7433096PubMed
7,320,200Posttranscriptional defects in beta-globin messenger RNA metabolism in beta-thalassemia: abnormal accumulation of beta-messenger RNA precursor sequences.J Clin Invest1981https://conductscience.org/library/papers/7320200PubMed
6,959,120Identification of human genomic clones coding the major histocompatibility antigens HLA-a2 and HLA-B7 by DNA-mediated gene transfer.Proc Natl Acad Sci U S A1982https://conductscience.org/library/papers/6959120PubMed
6,943,581Localization of a unique gene by direct hybridization in situ.Proc Natl Acad Sci U S A1981https://conductscience.org/library/papers/6943581PubMed

1 to 10 of 110

See all 110 cited by

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data30

The data bank entries PubMed's record names. Trial numbers are under Trials.

Data bankAccessionSource
GENBANKJ00093GENBANK
GENBANKJ00094GENBANK
GENBANKJ00096GENBANK
GENBANKJ00158GENBANK
GENBANKJ00159GENBANK
GENBANKJ00160GENBANK
GENBANKJ00161GENBANK
GENBANKJ00162GENBANK
GENBANKJ00163GENBANK
GENBANKJ00164GENBANK

1 to 10 of 30

See all 30 data

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this paper from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/papers/v1/345245

GET https://conductscience.org/api/papers/v1/345245/references?page=2

API referenceFor AI assistants