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Paper3551925

Cytosolic ratios of free [NADPH]/[NADP+] and [NADH]/[NAD+] in mouse pancreatic islets, and nutrient-induced insulin secretion.

Hedeskov CJ and 2 others. Biochem J, 1987. Cited by 67 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Cytosolic ratios of free [NADPH]/[NADP+] and [NADH]/[NAD+] in mouse pancreatic islets, and nutrient-induced insulin secretion. Papers, record 3551925. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/3551925

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Cytosolic ratios of free [NADPH]/[NADP+] and [NADH]/[NAD+] in mouse pancreatic islets, and nutrient-induced insulin secretion.
PubMed
Journal
Biochem J
PubMed
Year
1987
PubMed
Publication types
Journal Article, Research Support, Non-U.S. Gov't
PubMed
Citations, by iCite
67
iCite
Relative citation ratio, by iCite
1.58
iCite
Revised in PubMed
2019-05-01
PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Hedeskov CJC J
2Capito KK
3Thams PP

Source PubMed

Topics13

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
InsulinMajor topic
Islets of LangerhansMajor topic
NADMajor topic
NADPMajor topic
Animals
Carboxylic Acids
Cytosol
Fructose
Glucose
Glutamine
Leucine
Male
Mice

Source PubMed

References34

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
16,247,727Mechanism of glucose-induced insulin secretion.Physiol Rev1980https://conductscience.org/library/papers/6247727PubMed
22,988,501Effect of glucose on polyphosphoinositide metabolism in isolated rat islets of Langerhans.Biochem J1985https://conductscience.org/library/papers/2988501PubMed
36,357,895Effects of nutrient secretagogues upon phospholipid metabolism in rat pancreatic islets.Mol Cell Endocrinol1983https://conductscience.org/library/papers/6357895PubMed
47,024,025On insulin secretion.Diabetologia1981https://conductscience.org/library/papers/7024025PubMed
57,039,687The stimulus-secretion coupling of glucose-induced insulin release. Thiol: disulfide balance in pancreatic islets.Biochimie1982https://conductscience.org/library/papers/7039687PubMed
67,047,526The stimulus-secretion coupling of amino acid-induced insulin release. Metabolic response of pancreatic islets of L-glutamine and L-leucine.J Biol Chem1982https://conductscience.org/library/papers/7047526PubMed
77,115,406The redox state of pyridine nucleotides controls permeability of uncoupled mitochondria to K+.Biochem Biophys Res Commun1982https://conductscience.org/library/papers/7115406PubMed
86,759,632The electrogenic sodium-potassium pump of mouse pancreatic B-cells.J Physiol1982https://conductscience.org/library/papers/6759632PubMed
94,291,787The redox state of free nicotinamide-adenine dinucleotide in the cytoplasm and mitochondria of rat liver.Biochem J1967https://conductscience.org/library/papers/4291787PubMed
104,870,741Metabolism of glucose in the islets of Langerhans.J Biol Chem1968https://conductscience.org/library/papers/4870741PubMed
114,391,039The redox state of free nicotinamide-adenine dinucleotide phosphate in the cytoplasm of rat liver.Biochem J1969https://conductscience.org/library/papers/4391039PubMed
124,313,804Insulin release by isolated pancreatic islets of the mouse incubated in vitro.Diabetologia1969https://conductscience.org/library/papers/4313804PubMed
134,335,545The effect of mannoheptulose on glucose- and pyruvate-stimulated oxygen uptake in normal mouse pancreatic islets.Biochim Biophys Acta1971https://conductscience.org/library/papers/4335545PubMed
144,577,291Ultrastructural morphometry of the pancreatic -cell.Diabetologia1973https://conductscience.org/library/papers/4577291PubMed
154,148,924Time course studies of glucose-induced changes in glucose-6-phosphate and fructose-1,6-diphosphate content of mouse and rat pancreatic islets.Diabetologia1973https://conductscience.org/library/papers/4148924PubMed
164,149,332Effect of carbohydrates upon fluorescence of reduced pyridine nucleotides from perifused isolated pancreatic islets.Diabetologia1973https://conductscience.org/library/papers/4149332PubMed
171,095,720Electrical characteristics of pancreatic islet cells.J Physiol1975https://conductscience.org/library/papers/1095720PubMed
1821,628Pyridine nucleotide distributions and enzyme mass action ratios in hepatocytes from fed and starved rats.Arch Biochem Biophys1977https://conductscience.org/library/papers/21628PubMed
19340,960D-glucose inhibits potassium efflux from pancreatic islet cells.Nature1978https://conductscience.org/library/papers/340960PubMed
20205,753Effects of glucose and acetylcholine on islet tissue NADH and insulin release.Life Sci1978https://conductscience.org/library/papers/205753PubMed

See all 34 references

Cited by30

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 67 citations.

PMIDTitleJournalYearIn PapersSource
41,347,142Loss of Nocturnin increases neuronal viability in oxidative stress conditions.Front Neurosci2025https://conductscience.org/library/papers/41347142PubMed
40,550,364Retinoid dynamics in vision: from visual cycle biology to retina disease treatments.Pharmacol Ther2025https://conductscience.org/library/papers/40550364PubMed
37,980,339Inferring mitochondrial and cytosolic metabolism by coupling isotope tracing and deconvolution.Nat Commun2023https://conductscience.org/library/papers/37980339PubMed
37,938,890Kinetic modelling of β-cell metabolism reveals control points in the insulin-regulating pyruvate cycling pathways.IET Syst Biol2023https://conductscience.org/library/papers/37938890PubMed
37,600,713A pathway model of glucose-stimulated insulin secretion in the pancreatic β-cell.Front Endocrinol (Lausanne)2023https://conductscience.org/library/papers/37600713PubMed
36,269,889Targeting Apollo-NADP+ to Image NADPH Generation in Pancreatic Beta-Cell Organelles.ACS Sens2022https://conductscience.org/library/papers/36269889PubMed
35,103,852Monitoring NAD(H) and NADP(H) dynamics during organismal development with genetically encoded fluorescent biosensors.Cell Regen2022https://conductscience.org/library/papers/35103852PubMed
34,034,730Stepwise metabolic engineering of Candida tropicalis for efficient xylitol production from xylose mother liquor.Microb Cell Fact2021https://conductscience.org/library/papers/34034730PubMed
30,903,027Spatial-fluxomics provides a subcellular-compartmentalized view of reductive glutamine metabolism in cancer cells.Nat Commun2019https://conductscience.org/library/papers/30903027PubMed
30,258,175Analysis of redox landscapes and dynamics in living cells and in vivo using genetically encoded fluorescent sensors.Nat Protoc2018https://conductscience.org/library/papers/30258175PubMed
29,809,136Semisynthetic biosensors for mapping cellular concentrations of nicotinamide adenine dinucleotides.Elife2018https://conductscience.org/library/papers/29809136PubMed
28,581,494Genetically encoded fluorescent sensors reveal dynamic regulation of NADPH metabolism.Nat Methods2017https://conductscience.org/library/papers/28581494PubMed
26,786,775Thymoquinone, a bioactive component of Nigella sativa, normalizes insulin secretion from pancreatic β-cells under glucose overload via regulation of malonyl-CoA.Am J Physiol Endocrinol Metab2016https://conductscience.org/library/papers/26786775PubMed
26,243,542Determination of the Cytosolic NADPH/NADP Ratio in Saccharomyces cerevisiae using Shikimate Dehydrogenase as Sensor Reaction.Sci Rep2015https://conductscience.org/library/papers/26243542PubMed
24,130,841A role for cytosolic isocitrate dehydrogenase as a negative regulator of glucose signaling for insulin secretion in pancreatic ß-cells.PLoS One2013https://conductscience.org/library/papers/24130841PubMed
22,297,553Long term intensive exercise training leads to a higher plasma malate/lactate dehydrogenase (M/L) ratio and increased level of lipid mobilization in horses.Vet Res Commun2012https://conductscience.org/library/papers/22297553PubMed
19,624,259Early neural and vascular dysfunctions in diabetic rats are largely sequelae of increased sorbitol oxidation.Antioxid Redox Signal2010https://conductscience.org/library/papers/19624259PubMed
19,251,047Insulin granule biogenesis, trafficking and exocytosis.Vitam Horm2009https://conductscience.org/library/papers/19251047PubMed
18,670,618Pancreatic beta-cell purification by altering FAD and NAD(P)H metabolism.Exp Diabetes Res2008https://conductscience.org/library/papers/18670618PubMed
16,321,791Glucose-sensing mechanisms in pancreatic beta-cells.Philos Trans R Soc Lond B Biol Sci2005https://conductscience.org/library/papers/16321791PubMed

See all 30 cited by

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

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Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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