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Paper · 3671071

A long polypyrimidine/polypurine tract induces an altered DNA conformation on the 3' coding region of the adjacent myosin heavy chain gene.

McCarthy JG and 1 other. Nucleic Acids Res, 1987. Cited by 29 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. A long polypyrimidine/polypurine tract induces an altered DNA conformation on the 3' coding region of the adjacent myosin heavy chain gene. Papers, record 3671071. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/3671071

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
A long polypyrimidine/polypurine tract induces an altered DNA conformation on the 3' coding region of the adjacent myosin heavy chain gene.
PubMed
Journal
Nucleic Acids Res
PubMed
Year
1987
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
29
iCite
Relative citation ratio, by iCite
0.6
iCite
Revised in PubMed
2019-05-01
PubMed

Authors2

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1McCarthy JGJ G
2Heywood SMS M

Source PubMed

Topics9

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
MyosinsMajor topic
Animals
Base Sequence
Chick Embryo
DNA, Recombinant
DNA, Superhelical
Genes
Molecular Sequence Data
Nucleic Acid Conformation

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References53

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
13,022,151A 3' enhancer is required for temporal and tissue-specific transcriptional activation of the chicken adult beta-globin gene.Nature1986https://conductscience.org/library/papers/3022151PubMed
22,411,549Nuclease S1-sensitive sites in multigene families: human U2 small nuclear RNA genes.EMBO J1985https://conductscience.org/library/papers/2411549PubMed
33,009,464The chicken myosin heavy chain family.J Biol Chem1986https://conductscience.org/library/papers/3009464PubMed
46,294,119Characterization of sarcomeric myosin heavy chain genes.J Biol Chem1983https://conductscience.org/library/papers/6294119PubMed
56,210,847Active chromatin.Nature1982https://conductscience.org/library/papers/6210847PubMed
62,989,280An equilibrium between distorted and undistorted DNA in the adult chicken beta A-globin gene.J Biol Chem1985https://conductscience.org/library/papers/2989280PubMed
76,209,712Human U1 RNA genes contain an unusually sensitive nuclease S1 cleavage site within the conserved 3' flanking region.Proc Natl Acad Sci U S A1984https://conductscience.org/library/papers/6209712PubMed
86,273,442Isolation of multiple genomic sequences coding for chicken myosin heavy chain protein.J Biol Chem1982https://conductscience.org/library/papers/6273442PubMed
96,308,469Association of an S1 nuclease-sensitive structure with short direct repeats 5' of Drosophila heat shock genes.Nature1983https://conductscience.org/library/papers/6308469PubMed
106,300,766The nuclease sensitivity of active genes.Nucleic Acids Res1983https://conductscience.org/library/papers/6300766PubMed

1 to 10 of 53

See all 53 references

Cited by13

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 29 citations.

PMIDTitleJournalYearIn PapersSource
39,716,145A novel role for nonactin: interfering with G-quadruplex in RET-driven medullary thyroid cancer.BMC Cancer2024https://conductscience.org/library/papers/39716145PubMed
31,287,873Single-molecule analysis of i-motif within self-assembled DNA duplexes and nanocircles.Nucleic Acids Res2019https://conductscience.org/library/papers/31287873PubMed
26,307,103Selective repression of RET proto-oncogene in medullary thyroid carcinoma by a natural alkaloid berberine.BMC Cancer2015https://conductscience.org/library/papers/26307103PubMed
24,662,821Involvement of G-quadruplex structures in regulation of human RET gene expression by small molecules in human medullary thyroid carcinoma TT cells.Oncogene2015https://conductscience.org/library/papers/24662821PubMed
23,326,389Possible regulatory roles of promoter g-quadruplexes in cardiac function-related genes - human TnIc as a model.PLoS One2013https://conductscience.org/library/papers/23326389PubMed
20,959,293Evidence of the formation of G-quadruplex structures in the promoter region of the human vascular endothelial growth factor gene.Nucleic Acids Res2011https://conductscience.org/library/papers/20959293PubMed
19,997,887In vitro footprinting of promoter regions within supercoiled plasmid DNA.Methods Mol Biol2010https://conductscience.org/library/papers/19997887PubMed
19,385,599The importance of negative superhelicity in inducing the formation of G-quadruplex and i-motif structures in the c-Myc promoter: implications for drug targeting and control of gene expression.J Med Chem2009https://conductscience.org/library/papers/19385599PubMed
9,443,873The GAA triplet-repeat expansion in Friedreich ataxia interferes with transcription and may be associated with an unusual DNA structure.Am J Hum Genet1998https://conductscience.org/library/papers/9443873PubMed
8,759,018De novo generation of simple sequence during gene amplification.Nucleic Acids Res1996https://conductscience.org/library/papers/8759018PubMed

1 to 10 of 13

See all 13 cited by

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data1

The data bank entries PubMed's record names. Trial numbers are under Trials.

Data bankAccession
GENBANKX06251

Source GENBANK

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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