Paper · 36769694

Towards the Clinical Application of Gene Therapy for Genetic Inner Ear Diseases.

Lahlou G and 4 others. J Clin Med, 2023. Cited by 24 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Towards the Clinical Application of Gene Therapy for Genetic Inner Ear Diseases. Papers, record 36769694. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/36769694

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Towards the Clinical Application of Gene Therapy for Genetic Inner Ear Diseases.; PubMed
Journal: J Clin Med; PubMed
Year: 2023; PubMed
Publication types: Journal Article, Review; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/36769694/; PubMed
DOI: https://doi.org/10.3390/jcm12031046; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC9918244/; PubMed
The journal: https://conductscience.org/library/journal-index/101606588; PubMed
Citations, by iCite: 24; iCite
Relative citation ratio, by iCite: 2.87; iCite
Revised in PubMed: 2024-09-12; PubMed

Authors5

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	ORCID iD
1	Lahlou G	Ghizlene	https://orcid.org/0000-0002-1067-045X
2	Calvet C	Charlotte	https://orcid.org/0000-0002-6163-9807
3	Giorgi M	Marie
4	Lecomte MJ	Marie-José
5	Safieddine S	Saaid

Source PubMed

Topics0

NLM's MeSH indexing of the paper, its major topics first.

None in this release.

Grants2

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes it	Agency	Country	NIH project	Stated by
ANR-18-RHUS-0007	Agence Nationale de la Recherche			PubMed
FPA IDA08	Fondation pour l'Audition			PubMed

Source PubMed

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References140

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	36,610,400	Cochlear transduction via cerebrospinal fluid delivery of AAV in non-human primates.	Mol Ther	2023	https://conductscience.org/library/papers/36610400	PubMed
2	34,910,522	Dual-vector gene therapy restores cochlear amplification and auditory sensitivity in a mouse model of DFNB16 hearing loss.	Sci Adv	2021	https://conductscience.org/library/papers/34910522	PubMed
3	23,587,925	Mouse otocyst transuterine gene transfer restores hearing in mice with connexin 30 deletion-associated hearing loss.	Mol Ther	2013	https://conductscience.org/library/papers/23587925	PubMed
4	24,191,945	Triple trans-splicing adeno-associated virus vectors capable of transferring the coding sequence for full-length dystrophin protein into dystrophic mice.	Hum Gene Ther	2014	https://conductscience.org/library/papers/24191945	PubMed
5	23,640,742	Persistent stapedial arteries in human: from phylogeny to surgical consequences.	Surg Radiol Anat	2013	https://conductscience.org/library/papers/23640742	PubMed
6	25,807,962	Adeno-associated virus at 50: a golden anniversary of discovery, research, and gene therapy success--a personal perspective.	Hum Gene Ther	2015	https://conductscience.org/library/papers/25807962	PubMed
7	27,606,440	Applications of CRISPR technologies in research and beyond.	Nat Biotechnol	2016	https://conductscience.org/library/papers/27606440	PubMed
8	29,315,675	Chemical modifications of nucleic acid drugs and their delivery systems for gene-based therapy.	Med Res Rev	2018	https://conductscience.org/library/papers/29315675	PubMed
9	36,639,728	Assessing and advancing the safety of CRISPR-Cas tools: from DNA to RNA editing.	Nat Commun	2023	https://conductscience.org/library/papers/36639728	PubMed
10	27,074,241	Advances in fetal surgery.	Einstein (Sao Paulo)	2016	https://conductscience.org/library/papers/27074241	PubMed

1 to 10 of 140

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Cited by17

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 24 citations.

PMID	Title	Journal	Year	In Papers	Source
42,649,271	Mapping the global trends and hotspots of research on gene therapy and hair cell regeneration for hearing loss: a comprehensive data-mining-based study.	Gene Ther	2026	https://conductscience.org/library/papers/42649271	PubMed
42,346,617	Genomic and Epigenomic Advances in Hearing Loss: Molecular Mechanisms, Diagnostics, and Emerging Therapies.	J Pers Med	2026	https://conductscience.org/library/papers/42346617	PubMed
42,318,138	Efficacy and safety of SENS-501, a dual-AAV otoferlin gene therapy, for DFNB9 congenital deafness.	Mol Ther Adv	2026	https://conductscience.org/library/papers/42318138	PubMed
42,137,272	Capsid-engineered AAV vector overcomes a key intracellular barrier and efficiently transduces spiral ganglion neurons in adult mice.	Mol Ther Adv	2026	https://conductscience.org/library/papers/42137272	PubMed
40,791,787	Optical method to preserve residual hearing in patients receiving a cochlear implant.	Front Audiol Otol	2024	https://conductscience.org/library/papers/40791787	PubMed
40,567,403	Micro-CT Analysis of Rodent Temporal Bones: Identifying Optimal Species for Otological Research.	Laryngoscope Investig Otolaryngol	2025	https://conductscience.org/library/papers/40567403	PubMed
40,251,388	Cell tropism of adeno-associated viruses within the mouse inner ear in vivo: from embryonic to adult stages.	Sci Rep	2025	https://conductscience.org/library/papers/40251388	PubMed
39,655,096	Efficiency of gene therapy for sensorineural hearing loss in mouse model: A meta-analysis.	Laryngoscope Investig Otolaryngol	2024	https://conductscience.org/library/papers/39655096	PubMed
39,641,274	In vivo AAV9-Myo7a gene rescue restores hearing and cholinergic efferent innervation in inner hair cells.	JCI Insight	2024	https://conductscience.org/library/papers/39641274	PubMed
39,625,555	Inner Ear Gene Therapy: An Overview from Bench to Bedside.	Mol Diagn Ther	2025	https://conductscience.org/library/papers/39625555	PubMed

1 to 10 of 17

See all 17 cited by

Genes9

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes	Source
KCNQ1	3,784	PubTator's text mining	https://conductscience.org/library/genes/3784	NCBI Gene
LHFPL5	222,662	PubTator's text mining	https://conductscience.org/library/genes/222662	NCBI Gene
OTOF	9,381	PubTator's text mining	https://conductscience.org/library/genes/9381	NCBI Gene
PCDH15	65,217	PubTator's text mining	https://conductscience.org/library/genes/65217	NCBI Gene
PJVK	494,513	PubTator's text mining	https://conductscience.org/library/genes/494513	NCBI Gene
STRC	161,497	PubTator's text mining	https://conductscience.org/library/genes/161497	NCBI Gene
TMC1	117,531	PubTator's text mining	https://conductscience.org/library/genes/117531	NCBI Gene
USH1C	10,083	PubTator's text mining	https://conductscience.org/library/genes/10083	NCBI Gene
WHRN	25,861	PubTator's text mining	https://conductscience.org/library/genes/25861	NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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