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Paper · 36922653

Ferroptotic mechanisms and therapeutic targeting of iron metabolism and lipid peroxidation in the kidney.

Bayır H and 4 others. Nat Rev Nephrol, 2023. Cited by 281 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Ferroptotic mechanisms and therapeutic targeting of iron metabolism and lipid peroxidation in the kidney. Papers, record 36922653. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/36922653

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Ferroptotic mechanisms and therapeutic targeting of iron metabolism and lipid peroxidation in the kidney.
PubMed
Journal
Nat Rev Nephrol
PubMed
Year
2023
PubMed
Publication types
Journal Article, Review, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural
PubMed
Citations, by iCite
281
iCite
Relative citation ratio, by iCite
30.2
iCite
Revised in PubMed
2026-10-30
PubMed

Authors5

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Bayır HHülyahttps://orcid.org/0000-0003-2361-4120
2Dixon SJScott J
3Tyurina YYYulia Y
4Kellum JAJohn Ahttps://orcid.org/0000-0003-1995-2653
5Kagan VEValerian E

Source PubMed

Topics6

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
IronMajor topic
FerroptosisMajor topic
Humans
Lipid Peroxidation
Oxidation-Reduction
Kidney

Source PubMed

Grants10

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated bySource
R01 CA266342NCI NIH HHSUnited StatesR01CA266342PubMed and NIHNIH RePORTER
UG3 DK114861NIDDK NIH HHSUnited StatesUG3DK114861PubMed and NIHNIH RePORTER
R01 CA165065NCI NIH HHSUnited StatesR01CA165065PubMed and NIHNIH RePORTER
U01 AI156924NIAID NIH HHSUnited StatesU01AI156924PubMed and NIHNIH RePORTER
P01 HL114453NHLBI NIH HHSUnited StatesP01HL114453PubMed and NIHNIH RePORTER
R01 AI145406NIAID NIH HHSUnited StatesR01AI145406PubMed and NIHNIH RePORTER
R01 GM122923NIGMS NIH HHSUnited StatesR01GM122923PubMed and NIHNIH RePORTER
R01NS076511NIHNIH RePORTER
R37NS061817NIHNIH RePORTER
U01AI156923NIHNIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References280

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
123,190,609Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models.Cell Death Dis2012https://conductscience.org/library/papers/23190609PubMed
224,899,309Pro-resolving lipid mediators are leads for resolution physiology.Nature2014https://conductscience.org/library/papers/24899309PubMed
336,109,647Hydropersulfides inhibit lipid peroxidation and ferroptosis by scavenging radicals.Nat Chem Biol2023https://conductscience.org/library/papers/36109647PubMed
46,059,205Laboratory and clinical evaluation of the mucolytic properties of acetylcysteine.Am Rev Respir Dis1967https://conductscience.org/library/papers/6059205PubMed
524,880,340Identification of erythroferrone as an erythroid regulator of iron metabolism.Nat Genet2014https://conductscience.org/library/papers/24880340PubMed
616,144,837Redox imbalance in cystine/glutamate transporter-deficient mice.J Biol Chem2005https://conductscience.org/library/papers/16144837PubMed
730,996,346Fatty acid transport protein 2 reprograms neutrophils in cancer.Nature2019https://conductscience.org/library/papers/30996346PubMed
833,665,270Lipidomics data showing the effect of lipofermata on myeloid-derived suppressor cells in the spleens of tumor-bearing mice.Data Brief2021https://conductscience.org/library/papers/33665270PubMed
933,558,472Characterization of ferroptosis in kidney tubular cell death under diabetic conditions.Cell Death Dis2021https://conductscience.org/library/papers/33558472PubMed
1010,652,280Early embryonic lethality of H ferritin gene deletion in mice.J Biol Chem2000https://conductscience.org/library/papers/10652280PubMed

1 to 10 of 280

See all 280 references

Cited by187

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 281 citations.

PMIDTitleJournalYearIn PapersSource
42,964,669Circadian rhythm dysregulation and ferroptosis in hypertension: mechanisms and therapeutic implications.Front Cardiovasc Med2026https://conductscience.org/library/papers/42964669PubMed
42,960,598NADPH oxidase-associated oxidative stress and ferroptosis-related injury in calcium oxalate-exposed renal tubular epithelial cells: pharmacological evidence for PI3K/AKT involvement.Ren Fail2026https://conductscience.org/library/papers/42960598PubMed
42,943,481Time-Series Multi-Omics Reveal Metabolic Reprogramming, Oxidative Stress and Programmed Cell Death in M. bovis-Infected Bovine Mammary Epithelial Cells.Microorganisms2026https://conductscience.org/library/papers/42943481PubMed
42,942,016Lipid Metabolism and Ferroptosis in Cancer: Regulatory Mechanisms, Alternative Splicing, and Therapeutic Implications.Int J Mol Sci2026https://conductscience.org/library/papers/42942016PubMed
42,939,868Metabolomic and Transcriptomic Changes in Porcine Cumulus-Oocyte Complexes Following Vitrification: Cysteinyl-Glycine as an Antioxidant Enhances the Quality of Vitrified Oocytes.Antioxidants (Basel)2026https://conductscience.org/library/papers/42939868PubMed
42,939,350The Iron-Mitochondria-Oligodendrocyte Axis: An Emerging Metabolic Framework for Alzheimer's Disease.Brain Sci2026https://conductscience.org/library/papers/42939350PubMed
42,920,733Metabolic reprogramming and metabolic homeostasis in podocyte injury: novel mechanistic insights and natural product therapies.Front Cell Dev Biol2026https://conductscience.org/library/papers/42920733PubMed
42,920,026Ferroptosis in health and disease.Mol Biomed2026https://conductscience.org/library/papers/42920026PubMed
42,908,614Mapping the aging kidney: a bibliometric atlas of cellular senescence and future frontiers since the 20th century.Front Nephrol2026https://conductscience.org/library/papers/42908614PubMed
42,807,112Artesunate alleviates cisplatin-induced nephrotoxicity by regulating tryptophan metabolism and inhibiting ferroptosis.Front Pharmacol2026https://conductscience.org/library/papers/42807112PubMed

1 to 10 of 187

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Genes1

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn Genes
GPX42,879PubTator's text mininghttps://conductscience.org/library/genes/2879

Source NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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