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Paper369806

Cefoxitin: a review of its antibacterial activity, pharmacological properties and therapeutic use.

Brogden RN and 3 others. Drugs, 1979. Cited by 41 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Cefoxitin: a review of its antibacterial activity, pharmacological properties and therapeutic use. Papers, record 369806. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/369806

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Cefoxitin: a review of its antibacterial activity, pharmacological properties and therapeutic use.
PubMed
Journal
Drugs
PubMed
Year
1979
PubMed
Publication types
Journal Article, Review
PubMed
Citations, by iCite
41
iCite
Relative citation ratio, by iCite
2.21
iCite
Revised in PubMed
2018-11-13
PubMed

Authors4

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Brogden RNR N
2Heel RCR C
3Speight TMT M
4Avery GSG S

Source PubMed

Topics8

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
BacteriaMajor topic
CefoxitinMajor topic
CephalosporinsMajor topic
Bacterial Infections
Drug Incompatibility
Drug Stability
Humans
Kinetics

Source PubMed

References93

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
1176,926Susceptibility of beta-hemolytic streptococci to 65 antibacterial agents.Antimicrob Agents Chemother1976https://conductscience.org/library/papers/176926PubMed
21,047,087Antistaphylococcal activity and beta-lactamase resistance of newer cephalosporins.J Infect Dis1976https://conductscience.org/library/papers/1047087PubMed
3949,182Activity of cefamandole and other cephalosporins against aerobic and anaerobic bacteria.Antimicrob Agents Chemother1976https://conductscience.org/library/papers/949182PubMed
4357,399Cefoxitin sodium in complicated urinary tract infection.J Antimicrob Chemother1978https://conductscience.org/library/papers/357399PubMed
5820,241In vitro evaluation of cefoxitin and cefamandole.Antimicrob Agents Chemother1976https://conductscience.org/library/papers/820241PubMed
6357,385Intravenous cefoxitin sodium in the treatment of urinary tract infections.J Antimicrob Chemother1978https://conductscience.org/library/papers/357385PubMed
7984,809Susceptibility of anaerobic bacteria to 23 antimicrobial agents.Antimicrob Agents Chemother1976https://conductscience.org/library/papers/984809PubMed
8193,441Susceptibility of Clostridium perfringens isolated from human infections to twenty antibiotics.Antimicrob Agents Chemother1977https://conductscience.org/library/papers/193441PubMed
9690,021Surgical considerations in skin and soft-tissue infections and osteomyelitis treated with cefoxitin sodium.J Antimicrob Chemother1978https://conductscience.org/library/papers/690021PubMed
10306,221Comparative activities of selected beta-lactam antibiotics against Haemophilus influenzae.Antimicrob Agents Chemother1978https://conductscience.org/library/papers/306221PubMed
11690,025Susceptibility of anaerobes to cefoxitin sodium and cephalothin.J Antimicrob Chemother1978https://conductscience.org/library/papers/690025PubMed
1277,405Tissue penetration by cephalosporins.Lancet1978https://conductscience.org/library/papers/77405PubMed
1320,919,420Cefuroxime, an in vitro Comparison with Six Other Cephalosporins.Proc R Soc Med1977https://conductscience.org/library/papers/20919420PubMed
14690,027Pharmacokinetics of cefoxitin sodium in normal subjects and in uraemic patients.J Antimicrob Chemother1978https://conductscience.org/library/papers/690027PubMed
15319,751Lysis if enterobacteria by cefoxitin, cefuroxime, and cephalothin.Antimicrob Agents Chemother1977https://conductscience.org/library/papers/319751PubMed
16357,381Cefoxitin sodium: a clinical and pharmacological study.J Antimicrob Chemother1978https://conductscience.org/library/papers/357381PubMed
17357,389Comparison of cefoxitin sodium and cefazolin.J Antimicrob Chemother1978https://conductscience.org/library/papers/357389PubMed
184,843,049An in vivo comparison of cefoxitin, a semi-synthetic cephamycin, with cephalothin.J Antibiot (Tokyo)1974https://conductscience.org/library/papers/4843049PubMed
19308,502beta-Lactamases of subspecies of Bacteroides fragilis.J Antimicrob Chemother1978https://conductscience.org/library/papers/308502PubMed
20357,382Clinical experience with cefoxitin sodium in immunologically compromised patients.J Antimicrob Chemother1978https://conductscience.org/library/papers/357382PubMed

See all 93 references

Cited by16

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 41 citations.

PMIDTitleJournalYearIn PapersSource
40,246,785Physiologically Based Modeling of Cefoxitin, Cefazolin, and Piperacillin Pharmacokinetics in Obese and Lean Rats.AAPS J2025https://conductscience.org/library/papers/40246785PubMed
39,273,421The Application of Green Solvents in the Synthesis of S-Heterocyclic Compounds-A Review.Int J Mol Sci2024https://conductscience.org/library/papers/39273421PubMed
38,870,837A validated LC-MS/MS method for simultaneous quantitation of piperacillin, cefazolin, and cefoxitin in rat plasma and twelve tissues.J Pharm Biomed Anal2024https://conductscience.org/library/papers/38870837PubMed
38,651,882Novel antimony-based antimicrobial drug targets membranes of Gram-positive and Gram-negative bacterial pathogens.Microbiol Spectr2024https://conductscience.org/library/papers/38651882PubMed
38,645,489Quercetin of huoxuehuayu tongluo decoction and azithromycin combination therapy effectively improves rat tubal factor infertility by inhibiting inflammation.Iran J Basic Med Sci2024https://conductscience.org/library/papers/38645489PubMed
31,591,127Antibiotic prophylaxis with high-dose cefoxitin in bariatric surgery: an observational prospective single center study.Antimicrob Agents Chemother2019https://conductscience.org/library/papers/31591127PubMed
27,519,493Cefminox versus Cefoxitin in Hysterectomy Prophylaxis : Clinical Efficacy and Serum and Tissue Concentrations.Clin Drug Investig1997https://conductscience.org/library/papers/27519493PubMed
26,612,473Complicated Intra-Abdominal Infections: The Old Antimicrobials and the New Players.Drugs2015https://conductscience.org/library/papers/26612473PubMed
22,246,211Population pharmacokinetics of prophylactic cefoxitin in patients undergoing colorectal surgery.Eur J Clin Pharmacol2012https://conductscience.org/library/papers/22246211PubMed
11,706,924Commonly used antibacterial and antifungal agents for hospitalised paediatric patients: implications for therapy with an emphasis on clinical pharmacokinetics.Paediatr Drugs2001https://conductscience.org/library/papers/11706924PubMed
7,396,472Effect of orally administered probenecid on the pharmacokinetics of cefoxitin.Antimicrob Agents Chemother1980https://conductscience.org/library/papers/7396472PubMed
7,387,820Cefoxitin: intravenous pharmacokinetics and intramuscular bioavailability in kwashiorkor.Br J Clin Pharmacol1980https://conductscience.org/library/papers/7387820PubMed
6,647,190Metronidazole v. cefoxitin in severe appendicitis--a trial to compare a single intraoperative dose of two antibiotics given intravenously.Postgrad Med J1983https://conductscience.org/library/papers/6647190PubMed
3,588,249Influence of protein binding and severity of illness on renal elimination of four cephalosporin drugs in intensive-care patients.Pharm Weekbl Sci1987https://conductscience.org/library/papers/3588249PubMed
487,957Treatment of infections due to nonsporing anaerobes.Drugs1979https://conductscience.org/library/papers/487957PubMed
37,064Cefuroxime: a review of its antibacterial activity, pharmacological properties and therapeutic use.Drugs1979https://conductscience.org/library/papers/37064PubMed

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

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  • Comments and corrections
  • Genes
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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