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Paper37064

Cefuroxime: a review of its antibacterial activity, pharmacological properties and therapeutic use.

Brogden RN and 3 others. Drugs, 1979. Cited by 45 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Cefuroxime: a review of its antibacterial activity, pharmacological properties and therapeutic use. Papers, record 37064. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/37064

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Cefuroxime: a review of its antibacterial activity, pharmacological properties and therapeutic use.
PubMed
Journal
Drugs
PubMed
Year
1979
PubMed
Publication types
Journal Article, Review
PubMed
Citations, by iCite
45
iCite
Relative citation ratio, by iCite
2.46
iCite
Revised in PubMed
2026-10-11
PubMed

Authors4

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Brogden RNR N
2Heel RCR C
3Speight TMT M
4Avery GSG S

Source PubMed

Topics20

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
BacteriaMajor topic
CephalosporinsMajor topic
Adult
Child
Drug Resistance, Microbial
Female
Furans
Gonorrhea
Humans
Hydrogen-Ion Concentration
Infant, Newborn
Kinetics
Osteomyelitis
Pregnancy
Probenecid
Respiratory Tract Infections
Sepsis
Surgical Wound Infection
Tissue Distribution
Urinary Tract Infections

Source PubMed

References90

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
1856,025Cefoxitin resistance to beta-lactamase: a major factor for susceptibility of bacteroides fragilis to the antibiotic.Antimicrob Agents Chemother1977https://conductscience.org/library/papers/856025PubMed
220,919,395Clinical evaluation of cefuroxime in patients with urinary tract infections.Proc R Soc Med1977https://conductscience.org/library/papers/20919395PubMed
3656,890The efficacy of cefuroxime for the treatment of acute gonorrhoea in men.Br J Vener Dis1978https://conductscience.org/library/papers/656890PubMed
4429,250Biliary excretion and tissue levels of cefuroxime. A study in eleven patients undergoing cholecystectomy.J Antimicrob Chemother1979https://conductscience.org/library/papers/429250PubMed
520,919,422A clinical and bacteriological study of cefuroxime.Proc R Soc Med1977https://conductscience.org/library/papers/20919422PubMed
6599,117Cefuroxime: antimicrobial activity, human pharmacokinetics and therapeutic efficacy.J Antimicrob Chemother1977https://conductscience.org/library/papers/599117PubMed
720,919,414Pharmacokinetic and clinical studies on cefuroxime.Proc R Soc Med1977https://conductscience.org/library/papers/20919414PubMed
8348,667In vitro activity of cefuroxime against Treponema pallidum.J Antimicrob Chemother1978https://conductscience.org/library/papers/348667PubMed
920,919,397Clinical studies in cefuroxime in the urological and surgical fields.Proc R Soc Med1977https://conductscience.org/library/papers/20919397PubMed
1020,919,385Activityin vitroof Cefuroxime and Six Other Antimicrobial Agents againstNeisseria gonorrhœœisolated in Belgium and Rwanda.Proc R Soc Med1977https://conductscience.org/library/papers/20919385PubMed
1120,919,427Clinical trials with cefuroxime in chest disease.Proc R Soc Med1977https://conductscience.org/library/papers/20919427PubMed
1220,919,388Treatment of Females with Acute Gonorrhœa using Cefuroxime.Proc R Soc Med1977https://conductscience.org/library/papers/20919388PubMed
1320,919,416Bioavailability of Cefuroxime in Various Sites including Bile, Sputum and Bone.Proc R Soc Med1977https://conductscience.org/library/papers/20919416PubMed
1420,919,381Preliminary clinical experience with cefuroxime: report on one hundred cases.Proc R Soc Med1977https://conductscience.org/library/papers/20919381PubMed
1520,919,415Cefuroxime: pharmacokinetic study in bronchial secretions.Proc R Soc Med1977https://conductscience.org/library/papers/20919415PubMed
1620,919,400Pharmacokinetic and clinical study of cefuroxime in infants.Proc R Soc Med1977https://conductscience.org/library/papers/20919400PubMed
1728,561beta-lactamases in bacteroides.Scand J Infect Dis Suppl1978https://conductscience.org/library/papers/28561PubMed
18369,806Cefoxitin: a review of its antibacterial activity, pharmacological properties and therapeutic use.Drugs1979https://conductscience.org/library/papers/369806PubMed
191,259,406Comparative study of the in vitro antibacterial activity of cefoxitin, cefuroxine, and cephaloridine.Antimicrob Agents Chemother1976https://conductscience.org/library/papers/1259406PubMed
20883,818Cefuroxime, a new parenteral cephalosporin: collaborative in vitro susceptibility comparison with cephalothin against 5,887 clinical bacterial isolates.Antimicrob Agents Chemother1977https://conductscience.org/library/papers/883818PubMed

See all 90 references

Cited by12

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 45 citations.

PMIDTitleJournalYearIn PapersSource
40,604,654Metabolic evaluation and disease characteristics of urolithiasis in children from 2020 to 2024: a retrospective single-center study at the national children's medical center.BMC Pediatr2025https://conductscience.org/library/papers/40604654PubMed
37,153,397The effect of antibiotic prophylaxis on the incidence of surgical site infection after laparoscopic appendectomy for chronic appendicitis.Heliyon2023https://conductscience.org/library/papers/37153397PubMed
31,487,057Physiologically based pharmacokinetic evaluation of cefuroxime in perioperative antibiotic prophylaxis.Br J Clin Pharmacol2019https://conductscience.org/library/papers/31487057PubMed
26,612,473Complicated Intra-Abdominal Infections: The Old Antimicrobials and the New Players.Drugs2015https://conductscience.org/library/papers/26612473PubMed
11,706,924Commonly used antibacterial and antifungal agents for hospitalised paediatric patients: implications for therapy with an emphasis on clinical pharmacokinetics.Paediatr Drugs2001https://conductscience.org/library/papers/11706924PubMed
11,022,795Clinical use of cefuroxime in paediatric community-acquired pneumonia.Paediatr Drugs2000https://conductscience.org/library/papers/11022795PubMed
10,930,968First trimester exposure to cefuroxime: a prospective cohort study.Br J Clin Pharmacol2000https://conductscience.org/library/papers/10930968PubMed
8,799,689Cefuroxime axetil. A review of its antibacterial activity, pharmacokinetic properties and therapeutic efficacy.Drugs1996https://conductscience.org/library/papers/8799689PubMed
8,186,065The renal clearance of cefuroxime and ceftazidime and the effect of probenecid on their tubular excretion.Br J Clin Pharmacol1994https://conductscience.org/library/papers/8186065PubMed
7,684,677Cefetamet pivoxil. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.Drugs1993https://conductscience.org/library/papers/7684677PubMed
7,065,695Cefuroxime in the treatment of neonates.Arch Dis Child1982https://conductscience.org/library/papers/7065695PubMed
3,524,428Randomized comparison of cefamandole, cefazolin, and cefuroxime prophylaxis in open-heart surgery.Antimicrob Agents Chemother1986https://conductscience.org/library/papers/3524428PubMed

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

  • Grants
  • Trials
  • Comments and corrections
  • Genes
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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