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Paper · 37398564

The Wnt/β-catenin signaling pathway plays a role in drug-induced liver injury by regulating cytochrome P450 2E1 expression.

Shin YS and 7 others. Toxicol Res, 2023. Cited by 11 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. The Wnt/β-catenin signaling pathway plays a role in drug-induced liver injury by regulating cytochrome P450 2E1 expression. Papers, record 37398564. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/37398564

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
The Wnt/β-catenin signaling pathway plays a role in drug-induced liver injury by regulating cytochrome P450 2E1 expression.
PubMed
Journal
Toxicol Res
PubMed
Year
2023
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
11
iCite
Relative citation ratio, by iCite
1.43
iCite
Revised in PubMed
2024-07-02
PubMed

Authors8

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Shin YSYoo-Sub
2Hwang DBDa-Bin
3Won DHDong-Hoon
4Kim SYShin-Young
5Kim CChanguk
6Park JWJun Won
7Jeon YYoung
8Yun JWJun-Wonhttps://orcid.org/0000-0002-0155-4190

Source PubMed

Topics0

NLM's MeSH indexing of the paper, its major topics first.

None in this release.

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References55

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
112,570,712Cisplatin biochemical mechanism of action: from cytotoxicity to induction of cell death through interconnections between apoptotic and necrotic pathways.Curr Med Chem2003https://conductscience.org/library/papers/12570712PubMed
215,458,572Peroxynitrite decomposition catalyst ameliorates renal damage and protein nitration in cisplatin-induced nephrotoxicity in rats.BMC Pharmacol2004https://conductscience.org/library/papers/15458572PubMed
319,275,551Role of NF-kappaB in the regulation of cytochrome P450 enzymes.Curr Drug Metab2009https://conductscience.org/library/papers/19275551PubMed
422,511,898Revision and update on clinical practice guideline for liver cirrhosis.Korean J Hepatol2012https://conductscience.org/library/papers/22511898PubMed
516,496,347Zonal gene expression in murine liver: lessons from tumors.Hepatology2006https://conductscience.org/library/papers/16496347PubMed
622,185,839Cytochrome P-450 CYP2E1 knockout mice are protected against high-fat diet-induced obesity and insulin resistance.Am J Physiol Endocrinol Metab2012https://conductscience.org/library/papers/22185839PubMed
716,799,984Enhancement by pyrazole of lipopolysaccharide-induced liver injury in mice: role of cytochrome P450 2E1 and 2A5.Hepatology2006https://conductscience.org/library/papers/16799984PubMed
89,772,215Protection against acetaminophen toxicity in CYP1A2 and CYP2E1 double-null mice.Toxicol Appl Pharmacol1998https://conductscience.org/library/papers/9772215PubMed
922,670,697Wnt/beta-catenin signaling: a promising new target for fibrosis diseases.Physiol Res2012https://conductscience.org/library/papers/22670697PubMed
1033,948,989Incidence, characteristics and risk factors for drug-induced liver injury in hospitalized patients: A matched case-control study.Br J Clin Pharmacol2021https://conductscience.org/library/papers/33948989PubMed

Cited by9

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 11 citations.

PMIDTitleJournalYearIn PapersSource
42,872,022Divergent Hypoxia-Inducible Factor 2‑Alpha Signaling in Alcoholic Liver Disease and Metabolic Dysfunction-Associated Steatotic Liver Disease.ACS Pharmacol Transl Sci2026https://conductscience.org/library/papers/42872022PubMed
42,259,768CYP2E1 and CYP2D6 in Anti-Tuberculosis Drug-Induced Liver Injury: Mechanisms, Epigenetic Regulation, and Translational Implications.Clin Transl Sci2026https://conductscience.org/library/papers/42259768PubMed
41,249,771Exploring the roles of cytochrome P450 enzymes and their inhibitors in cancers and non-neoplastic human diseases.Arch Pharm Res2025https://conductscience.org/library/papers/41249771PubMed
40,817,410The dual roles of peptidoglycans: NOD1 and NOD2 inversely regulate bone metabolism.Exp Mol Med2025https://conductscience.org/library/papers/40817410PubMed
40,157,625Inhibition of bromodomain and extra-terminal (BET) proteins with JQ1 exacerbates acetaminophen-induced hepatotoxicity by altering detoxification pathways and oxidative stress responses.Chem Biol Interact2025https://conductscience.org/library/papers/40157625PubMed
39,939,490Inhibitory effects of cornuside on human liver cytochrome P450 enzymes.Naunyn Schmiedebergs Arch Pharmacol2025https://conductscience.org/library/papers/39939490PubMed
39,391,981Atractylodes Lancea and Its Constituent, Atractylodin, Ameliorates Metabolic Dysfunction-Associated Steatotic Liver Disease via AMPK Activation.Biomol Ther (Seoul)2024https://conductscience.org/library/papers/39391981PubMed
38,430,357Preparation and characterization of Sorafenib nano-emulsion: impact on pharmacokinetics and toxicity; an in vitro and in vivo study.Drug Deliv Transl Res2024https://conductscience.org/library/papers/38430357PubMed
37,779,594Effects of toxicants on endoplasmic reticulum stress and hepatic cell fate determination.Toxicol Res2023https://conductscience.org/library/papers/37779594PubMed

Genes0

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

None in this release.

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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